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Irwin Naturals · Other Combinations supplement

Stress-Defy

29 ingredients on file in the NIH Dietary Supplement Label Database, top 7% by ingredient count. Currently on-market in the U.S.

29
Ingredients
Top 7%
By ingredient count
11
Nutrient categories

Stress-Defy is a other combinations supplement by Irwin Naturals in softgel capsule form, listing 29 ingredients in the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. Currently listed as on-market. Daily Value percentages shown below are based on FDA reference daily intake amounts for adults.

Product Details

Form
Softgel Capsule
Database Entry Date
2025-01-23
Ingredients
29

Supplement Facts (29 Ingredients)

Calories
Amount
Not disclosed on label
% DV
Not reported
Total Fat
Amount
Not disclosed on label
% DV
Not reported
Total Carbohydrates
Amount
Not disclosed on label
% DV
Not reported
Protein
Amount
Not disclosed on label
% DV
Not reported
Thiamine
Amount
Not disclosed on label
% DV
Not reported
Riboflavin
Amount
Not disclosed on label
% DV
Not reported
Vitamin B6
Amount
Not disclosed on label
% DV
Not reported
Calcium
Amount
Not disclosed on label
% DV
Not reported
Magnesium
Amount
Not disclosed on label
% DV
Not reported
Flaxseed Oil
Amount
Not disclosed on label
% DV
Not reported
Chinese Skullcap root extract
Amount
Not disclosed on label
% DV
Not reported
Holy Basil Herb Extract
Amount
Not disclosed on label
% DV
Not reported
Ginkgo Leaf Extract
Amount
Not disclosed on label
% DV
Not reported
L-Theanine
Amount
Not disclosed on label
% DV
Not reported
Rhodiola Root Extract
Amount
Not disclosed on label
% DV
Not reported
Rosavins
Amount
Not disclosed on label
% DV
Not reported
Salidrosides
Amount
Not disclosed on label
% DV
Not reported
GABA
Amount
Not disclosed on label
% DV
Not reported
BioPerine Complex
Amount
Not disclosed on label
% DV
Not reported
Gelatin
Amount
Not disclosed on label
% DV
Not reported
Water, Purified
Amount
Not disclosed on label
% DV
Not reported
Glycerin
Amount
Not disclosed on label
% DV
Not reported
Soy Lecithin
Amount
Not disclosed on label
% DV
Not reported
Beeswax
Amount
Not disclosed on label
% DV
Not reported
Maltodextrin
Amount
Not disclosed on label
% DV
Not reported
Titanium Dioxide
Amount
Not disclosed on label
% DV
Not reported
Turmeric
Amount
Not disclosed on label
% DV
Not reported
Sodium Copper Chlorophyllin
Amount
Not disclosed on label
% DV
Not reported
Silicon Dioxide
Amount
Not disclosed on label
% DV
Not reported

How does Stress-Defy compare?

Ingredients listed on each label, against the other combinations category average of 21.8. Data from the NIH DSLD.

Stress-Defy29
1,000 mg Vitamin C Acai Berry34
Other Combinations average21.8

Stress-Defy lists 5 ingredients fewer than 1,000 mg Vitamin C Acai Berry. That is 7 above the other combinations average.

What the Label Data Shows

According to NIH DSLD label rows, Stress-Defy sits in the top 7% of products with a countable formula by declared ingredient count.

With 29 ingredients on the label, Stress-Defy is one of the more extensive other combinations supplement formulas from Irwin Naturals in the NIH Dietary Supplement Label Database (DSLD), sold in softgel capsule form. These ingredients span 11 nutrient categories, mineral, botanical, non-nutrient/non-botanical, other, and 7 more, reflecting a multi-component formula rather than a single-nutrient product.

Across a broader 29-ingredient formula, 29 of 29 do not carry a reported percentage Daily Value in the source record. That missing field does not establish whether an FDA reference value exists.

Availability status shapes how this label record is best used. This product is currently listed as on-market in the DSLD, with its label first entered into the database on 2025-01-23. This product is actively distributed in the U.S. right now. As with every DSLD entry, that listing reflects the manufacturer's self-declared label, not an independent safety or efficacy review.

About the DSLD database

The DSLD is a label database, not an FDA approval list, under the 1994 DSHEA framework, dietary supplements do not require pre-market approval, and label information reflects what manufacturers self-declare rather than independent laboratory verification. This page presents factual label data for reference only and is not medical advice; consult a licensed healthcare provider before making decisions about any supplement.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) Supplement label data for Stress-Defy: ingredients, % Daily Value, market status, brand · 2026 DSLD captures manufacturer-self-declared label information; the NIH does not verify accuracy or evaluate safety/efficacy. Dietary supplements are regulated under DSHEA 1994, no pre-market FDA approval is required.

Nationwide supplements with similar label profiles

Two DSLD-derived peer sets for Stress-Defy, both outside the Irwin Naturals brand so the neighborhoods are not catalog containment (the same-type Nearby block above stays type-local).

Ingredient Breakdown by Category

mineral
5
Calcium, Magnesium, Titanium Dioxide, +2 more
botanical
5
Chinese Skullcap root extract, Holy Basil Herb Extract, Ginkgo Leaf Extract, +2 more
non-nutrient/non-botanical
4
L-Theanine, Rosavins, Salidrosides, +1 more
other
3
Calories, Water, Purified, Glycerin
fat
3
Total Fat, Flaxseed Oil, Soy Lecithin
vitamin
3
Thiamine, Riboflavin, Vitamin B6
protein
2
Protein, Gelatin
sugar
1
Total Carbohydrates
blend
1
BioPerine Complex
animal part or source
1
Beeswax
complex carbohydrate
1
Maltodextrin

Daily Value Coverage

0
Above 100% DV
0
Below 100% DV
29
%DV not reported in source

Frequently Asked Questions

What ingredients are in Stress-Defy?
Stress-Defy contains 29 ingredients. By declared ingredient count it sits in the top 7% of DSLD products PlainVitamins places. Ingredients span 11 categories: mineral, botanical, non-nutrient/non-botanical, other, fat, vitamin, protein, sugar, blend, animal part or source, complex carbohydrate.
Who manufactures Stress-Defy?
Stress-Defy is currently manufactured by Irwin Naturals. It is classified as a Other Combinations supplement in softgel capsule form.
Is Stress-Defy still available for purchase?
Yes, Stress-Defy is currently listed as on-market in the NIH DSLD database.
What is the serving size of Stress-Defy?
The serving size is not specified.
What type of supplement is Stress-Defy?
Stress-Defy is classified as a "Other Combinations" supplement in the NIH database. This category includes products primarily composed of other combinations ingredients. DSLD sorts every supplement into one of 9 categories overall: Vitamin, Mineral, Botanical, Amino Acid & Protein, Non-Nutrient, Fat & Fatty Acid, Multi-Vitamin & Mineral, Botanical with Nutrients, or Other Combinations.
Data Sources & Methodology

Data as of 2025. Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD).

Supplement label data sourced from the Source: NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD contains label information from dietary supplement products marketed in the United States.

Daily Value (DV) percentages are based on Source: FDA 21 CFR 101.9 Reference Daily Intake (RDI) values for adults. Products marked "Off Market" may no longer be available for purchase but their label data remains in the database for reference.

Disclaimer, Not Medical Advice

Label data from the Source: NIH Dietary Supplement Label Database (DSLD). This information is for educational and reference purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or combining any dietary supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. This page draws directly on the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.