St. John's Wort with Folate and B12
by Metagenics · tablet or pill · 60 tablets
- On the market (NIH)
- UPC 7 55571 91594 8
- DSLD label 216246
- Serving 1 tablet
- 60 servings
St. John's Wort with Folate and B12 by Metagenics lists 3 ingredients, 3 with an amount per serving of 1 tablet, such as 665 mcg DFE of folate, 250 mcg of vitamin B12 and 450 mg of St. John's wort (hypericum perforatum L.) aerial parts extract. Its current label entered the NIH Dietary Supplement Label Database on March 24, 2020.
What is in St. John's Wort with Folate and B12?
Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Folateas Calcium L-5-MethyltetrahydrofolateFolate (Form: as Calcium L-5-Methyltetrahydrofolate (Alt. Name: Metafolin)) | 665 mcg DFE | 166% | |
| Vitamin B12as MethylcobalaminVitamin B12 (Form: as Methylcobalamin) | 250 mcg | 10,417% | Higher than 77% of 14,425 products listing vitamin B12 (median 36 mcg). |
| St. John's Wort (Hypericum perforatum L.) aerial parts extractas HypericinsSt. John's Wort (Hypericum perforatum L.) aerial parts extract (Form: standardized to 0.3% Hypericins Note: 1.35 mg) PlantPart: aerial parts Genus: Hypericum Species: perforatum Classifier: L. | 450 mg | Higher than 69% of 338 products listing St. John's wort (median 300 mg). |
Source: NIH ODS Dietary Supplement Label Database, label 216246 (entered March 24, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.
The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
The products whose ingredient lists overlap most with St. John's Wort with Folate and B12's, rare ingredients counting for more.
- Hypericum Perforatum III St. John's Wort ExtractHBC Protocols 3 shared, 64% alike
- St. John's Wort With B Vitamins And Folic AcidHBC Protocols 3 shared, 64% alike
- St. John's WortVitamin World 1 shared, 55% alike
- Double Strength St. John's Wort 300 mgNature's Bounty · off the market 1 shared, 55% alike
- St. John's Wort 300 mgVitaCeutical Labs 1 shared, 55% alike
- St. John's Wort 300 mgVitabase 1 shared, 55% alike
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Directions: Use as directed by your healthcare practitioner. Recommend to take on an empty stomach.
- Warnings
- Warning: Do not use if pregnant or nursing.
- Do not use before surgery.
- Caution: If taking medication-including blood thinning medication or any medication related to mood modulation-consult your healthcare practitioner before use.
- Avoid excessive exposure to UV irradiation (e.g., sunlight; tanning) when using this product.
- Keep out of the reach of children.
- Allergens and what it does not contain
- This product is non-GMO, gluten-free, and vegetarian.
- Storage
- Storage: Keep tightly closed in a cool, dry place.
Source: label statements in DSLD label 216246.
What else is on the label?
Other ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Silica, Stearic Acid, Coating.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GF Certified Gluten-free. Listed with: Certified gluten-free (GFCO) (a seal is the label's claim; the certifier's own list confirms it).
How many labels does St. John's Wort with Folate and B12 have?
3 labels are on file under this name since November 25, 2013: other sizes, label designs and reformulations. The current one leads this page.
- Label 216246 (current) Entered March 24, 2020 · on the market · 60 tablets · UPC 7 55571 91594 8
- Label 209651 Entered December 22, 2019 · off the market December 27, 2019 · 60 tablets
- Label 27875 Entered November 25, 2013 · off the market July 24, 2018 · 60 tablets · UPC 7 55571 91594 8
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Metagenics (manufacturer), Gig Harbor, WA. All Metagenics products.