SAMe 100 mg
by NOW · tablet or pill · 60 tablets
- On the market (NIH)
- UPC 7 33739 00136 8
- DSLD label 53387
- Serving 1 tablet
SAMe 100 mg by NOW lists one ingredient: 100 mg of SAMe per serving of 1 tablet. Its current label entered the NIH Dietary Supplement Label Database on November 24, 2015.
What is in SAMe 100 mg?
Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| SAMeas S-Adenosyl-L-Methionine Disulfate TosylateSAMe (Form: from S-Adenosyl-L-Methionine Disulfate Tosylate) (Alt. Name: S-Adenosyl-L-Methionine) | 100 mg | 82% of 163 products listing SAMe give more (median 200 mg). Per day at the most servings: 400 mg. |
Source: NIH ODS Dietary Supplement Label Database, label 53387 (entered November 24, 2015), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.
The NIH database records 2 to 4 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
6 products list the very same ingredients; the nearest amounts come first.
- SAM-eNature's Craft same ingredients
- SAM-e 200 mgGNC · off the market same ingredients
- SAM-e 200 mgVitabase same ingredients
- SAMe Iso Active 200 mgNatural Factors · off the market same ingredients
- Ultra SAMePhysician's Preference · off the market same ingredients
- SAM-e 200 mgMartin Avenue Pharmacy same ingredients
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Suggested Usage: Take 1 tablet 2 to 4 times daily, preferably on an empty stomach.
- Warnings
- Caution: For adults only.
- Individuals with bipolar depression, anxiety disorders or taking antidepressant medications should not take SAMe unless under professional medical supervision. Consult physician if pregnant/nursing, taking medication, or have a medical condition.
- Keep out of reach of children.
- Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
- Do Not Eat Freshness Packets. Keep in Bottle.
- Allergens and what it does not contain
- Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish ingredients.
- Storage
- Refrigeration recommended after opening.
Source: label statements in DSLD label 53387.
What else is on the label?
Other ingredients: Cellulose, Croscarmellose Sodium, Magnesium Stearate, Silica, Stearic Acid, Ascorbic Acid, Citric Acid, Enteric Coating.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GMP QUALITY ASSURED.
How many labels does SAMe 100 mg have?
6 labels are on file under this name since October 1, 2012: other sizes, label designs and reformulations. The current one leads this page.
- Label 53387 (current) Entered November 24, 2015 · on the market · 60 tablets · UPC 7 33739 00136 8
- Label 53386 Entered November 24, 2015 · on the market · 30 tablets · UPC 7 33739 00135 1
- Label 26816 Entered October 25, 2013 · off the market October 23, 2015 · 60 tablets · UPC 7 33739 00136 8
- Label 26815 Entered October 25, 2013 · off the market October 23, 2015 · 30 tablets · UPC 7 33739 00135 1
- Label 13077 Entered October 25, 2012 · off the market November 6, 2012 · 60 tablets · UPC 7 33739 00136 8
- Label 13075 Entered October 1, 2012 · off the market November 6, 2012 · 30 tablets · UPC 7 33739 00135 1
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names NOW Foods (manufacturer), Bloomingdale, IL. All NOW products.