SAM-e
by Nature's Craft · capsule · 90 capsules
- On the market (NIH)
- DSLD label 296722
- Serving 1 capsule
- 90 servings
SAM-e by Nature's Craft lists one ingredient: 150 mg of SAMe per serving of 1 capsule. Its current label entered the NIH Dietary Supplement Label Database on August 23, 2023.
What is in SAM-e?
Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| SAMeas S-Adenosyl-L-Methionine Disulfate P-Tosylate | 150 mg | 79% of 163 products listing SAMe give more (median 200 mg). Per day at the most servings: 300 mg. |
Source: NIH ODS Dietary Supplement Label Database, label 296722 (entered August 23, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.
The NIH database records 1 to 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
6 products list the very same ingredients; the nearest amounts come first.
- SAM-e 200 mgGNC · off the market same ingredients
- SAM-e 200 mgVitabase same ingredients
- SAMe Iso Active 200 mgNatural Factors · off the market same ingredients
- Ultra SAMePhysician's Preference · off the market same ingredients
- SAM-e 200 mgMartin Avenue Pharmacy same ingredients
- SAM-e 200 mgup&up same ingredients
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Suggested Use: For adults, take one (1) capsule once or twice daily before a meal, or as directed by your physician. Do not take more than two (2) servings per day.
- Warnings
- Caution: Do not exceed recommended dose.
- Not intended for pregnant or nursing mothers.
- Not intended for children under 18 years of age.
- If you are taking medications (especially antidepressants), have a known medical condition, or are planning to have a medical procedure, consult your doctor before use.
- If you are taking medications (especially antidepressants), have a known medical condition, or are planning to have a medical procedure, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Individuals with bipolar disorder and manic depression should avoid this supplement.
- Keep out of the reach of children.
- Do not use if safety seal is damaged or missing.
- Storage
- Store in a cool, dry place.
Source: label statements in DSLD label 296722.
What else is on the label?
Other ingredients: Hypromellose, Rice Flour, Magnesium Stearate, Hydroxypropyl Methylcellulose, Propylene Glycol, Triacetin, Methacrylic Acid Copolymer.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Made in the USA with global ingredients 3rd party lab verified Sourced from a GMP certified facility.
How many labels does SAM-e have?
3 labels are on file under this name since October 22, 2021: other sizes, label designs and reformulations. The current one leads this page.
- Label 296722 (current) Entered August 23, 2023 · on the market · 90 capsules
- Label 260819 Entered February 23, 2022 · on the market · 60 capsules
- Label 256632 Entered October 22, 2021 · off the market June 14, 2022 · 90 capsules
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Nature's Craft (distributor), Pomona, NY. All Nature's Craft products.