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Natures Craft · Non-Nutrient/Non-Botanical supplement

SAM-e

5 ingredients on file in the NIH Dietary Supplement Label Database, top 75% by ingredient count. Off-market, label data preserved for reference.

5
Ingredients
Top 75%
By ingredient count
4
Nutrient categories
Off Market by Natures Craft Verify with NIH DSLD → · FDA overview →

SAM-e is a non-nutrient/non-botanical supplement by Natures Craft in capsule form, listing 5 ingredients in the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. Currently listed as off-market (no longer available for purchase, but label data is preserved). Daily Value percentages shown below are based on FDA reference daily intake amounts for adults.

Product Details

Form
Capsule
Database Entry Date
2021-10-22
Ingredients
5

Supplement Facts (5 Ingredients)

S-Adenosyl Methionine
SAMe
Amount
Not disclosed on label
% DV
Not reported
Hypromellose
Hypromellose
Amount
Not disclosed on label
% DV
Not reported
Rice Flour
Rice
Amount
Not disclosed on label
% DV
Not reported
Magnesium Stearate
Magnesium Stearate
Amount
Not disclosed on label
% DV
Not reported
Gellan Gum
Gellan
Amount
Not disclosed on label
% DV
Not reported

How does SAM-e compare?

Ingredients listed on each label, against the non-nutrient/non-botanical category average of 6.9. Data from the NIH DSLD.

SAM-e5
1 Andro Stenelone9
Non-Nutrient/Non-Botanical average6.9

SAM-e lists 4 ingredients fewer than 1 Andro Stenelone. That is 2 below the non-nutrient/non-botanical average.

What the Label Data Shows

According to NIH DSLD label rows, SAM-e sits in the top 75% of products with a countable formula by declared ingredient count.

SAM-e is a compact, 5-ingredient non-nutrient/non-botanical supplement from Natures Craft, sold in capsule form, cataloged in the NIH Dietary Supplement Label Database (DSLD). These ingredients span 4 nutrient categories, other, non-nutrient/non-botanical, botanical, complex carbohydrate, reflecting a multi-component formula rather than a single-nutrient product.

With only 5 ingredients on the label, 5 of 5 do not have a percentage Daily Value in this DSLD source record, which is not evidence that an FDA reference value does or does not exist.

Market status matters for supplement research. This product is currently listed as off-market in the DSLD, with its label first entered into the database on 2021-10-22. Once a product goes off-market, it is no longer manufactured or sold under this label, yet the DSLD keeps the record intact for historical reference, useful for researchers, anyone with an older bottle on hand, or tracking how formulations changed over time.

About the DSLD database

The DSLD is a label database, not an FDA approval list, under the 1994 DSHEA framework, dietary supplements do not require pre-market approval, and label information reflects what manufacturers self-declare rather than independent laboratory verification. This page presents factual label data for reference only and is not medical advice; consult a licensed healthcare provider before making decisions about any supplement.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) Supplement label data for SAM-e: ingredients, % Daily Value, market status, brand · 2026 DSLD captures manufacturer-self-declared label information; the NIH does not verify accuracy or evaluate safety/efficacy. Dietary supplements are regulated under DSHEA 1994, no pre-market FDA approval is required.

Nationwide supplements with similar label profiles

Two DSLD-derived peer sets for SAM-e, both outside the Natures Craft brand so the neighborhoods are not catalog containment (the same-type Nearby block above stays type-local).

Similar ingredient count

Nearest cross-brand formulas by declared ingredient count (5 here).

CALM Strawberry Mango Flavored · Natural Vitality 5 ing. Soybean Lecithin · SP Standard Process 5 ing. Vitamin D3 1000 IU with Vitamin K2 Grapefruit Flavor · Onnit 5 ing. Forskolin · California Products 5 ing. L-Glutamine 500 mg · Natural Grocers by Vitamin Cottage 5 ing. L-Glutathione 250 mg · Natural Grocers by Vitamin Cottage 5 ing. L-Glycine 500 mg · Natural Grocers by Vitamin Cottage 5 ing. Niacin 25 mg · Natural Grocers by Vitamin Cottage 5 ing.

Similar Capsule peers

Nearest same-form formulas from other brands.

Biotin 10,000 mcg · Micro Ingredients 5 ing. Niacin Flush Free 250 mg · Natural Grocers by Vitamin Cottage 5 ing. B6 100 mg · Natural Grocers by Vitamin Cottage 5 ing. Buffered C 500 mg · Natural Grocers by Vitamin Cottage 5 ing. D-Aspartic Acid 3000 mg · Micro Ingredients 5 ing. Hyaluronic Acid 100 mg · Natural Grocers by Vitamin Cottage 5 ing. Red Yeast Rice 600 mg · Natural Grocers by Vitamin Cottage 5 ing.

Ingredient Breakdown by Category

other
2
Hypromellose, Magnesium Stearate
non-nutrient/non-botanical
1
S-Adenosyl Methionine
botanical
1
Rice Flour
complex carbohydrate
1
Gellan Gum

Daily Value Coverage

0
Above 100% DV
0
Below 100% DV
5
%DV not reported in source

Frequently Asked Questions

What ingredients are in SAM-e? ▼
SAM-e contains 5 ingredients. By declared ingredient count it sits in the top 75% of DSLD products PlainVitamins places. Ingredients span 4 categories: other, non-nutrient/non-botanical, botanical, complex carbohydrate.
Who manufactures SAM-e? ▼
SAM-e is was manufactured by Natures Craft. It is classified as a Non-Nutrient/Non-Botanical supplement in capsule form.
Is SAM-e still available for purchase? ▼
According to the NIH DSLD database, SAM-e is listed as off-market and may no longer be available for purchase.
What is the serving size of SAM-e? ▼
The serving size is not specified.
What type of supplement is SAM-e? ▼
SAM-e is classified as a "Non-Nutrient/Non-Botanical" supplement in the NIH database. This category includes products primarily composed of non-nutrient/non-botanical ingredients. DSLD sorts every supplement into one of 9 categories overall: Vitamin, Mineral, Botanical, Amino Acid & Protein, Non-Nutrient, Fat & Fatty Acid, Multi-Vitamin & Mineral, Botanical with Nutrients, or Other Combinations.
Data Sources & Methodology

Data as of 2025. Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD).

Supplement label data sourced from the Source: NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD contains label information from dietary supplement products marketed in the United States.

Daily Value (DV) percentages are based on Source: FDA 21 CFR 101.9 Reference Daily Intake (RDI) values for adults. Products marked "Off Market" may no longer be available for purchase but their label data remains in the database for reference.

Disclaimer, Not Medical Advice

Label data from the Source: NIH Dietary Supplement Label Database (DSLD). This information is for educational and reference purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or combining any dietary supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Read our methodology , how this data is sourced, computed, and verified.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. This page draws directly on the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.