PlainVitamins

Pycnogenol Supreme

by Source Naturals · tablet or pill · 60 tablets

  • On the market (NIH)
  • UPC 0 21078 02220 6
  • DSLD label 275384
  • Serving 2 tablets
  • 30 servings

Pycnogenol Supreme by Source Naturals lists 30 ingredients, 30 with an amount per serving of 2 tablets, such as 500 mg of vitamin C, 200 mg of polygonum cuspidatum root extract, 150 mg of green tea leaf extract and 150 mg of proanthodyn, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on January 23, 2023.

What is in Pycnogenol Supreme?

Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Pycnogenol Supreme: Supplement Facts rows against the market (DSLD label 275384, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories10 Calories
Total Carbohydrates1 g1%Carbohydrate in Pycnogenol Supreme against 21,979 products1 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.1 g

74% of 21,979 products listing carbohydrate give more (median 3 g).

Vitamin Cas Ascorbic Acid500 mg555%Vitamin C in Pycnogenol Supreme against 18,583 products500 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg500 mg

Higher than 81% of 18,583 products listing vitamin C (median 100 mg).

Polygonum cuspidatum root extractas Resveratrol8% total resveratrols200 mgHu Zhang in Pycnogenol Supreme against 269 products200 mg per serving; the middle half of products list 50 mg to 400 mg, the median 150 mg.200 mg

Higher than 54% of 269 products listing hu zhang (median 150 mg).

Green Tea Leaf Extract150 mgGreen Tea in Pycnogenol Supreme against 2,595 products150 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.150 mg

Higher than 58% of 2,595 products listing green tea (median 100 mg).

Proanthodynas Grape seed extract150 mgProanthocyanidins in Pycnogenol Supreme against 164 products150 mg per serving; the middle half of products list 12.5 mg to 95 mg, the median 36 mg.150 mg

Higher than 87% of 164 products listing proanthocyanidins (median 36 mg).

Turmeric100 mgTurmeric in Pycnogenol Supreme against 2,369 products100 mg per serving; the middle half of products list 50 mg to 500 mg, the median 150 mg.100 mg

57% of 2,369 products listing turmeric give more (median 150 mg).

Rosemary leaf extract100 mgRosemary in Pycnogenol Supreme against 332 products100 mg per serving; the middle half of products list 25 mg to 100 mg, the median 50 mg.100 mg

Higher than 64% of 332 products listing rosemary (median 50 mg).

Lecithin100 mgLecithin in Pycnogenol Supreme against 804 products100 mg per serving; the middle half of products list 50 mg to 1,200 mg, the median 200 mg.100 mg

58% of 804 products listing lecithin give more (median 200 mg).

Bromelain100 mgBromelain in Pycnogenol Supreme against 1,337 products100 mg per serving; the middle half of products list 25 mg to 200 mg, the median 50 mg.100 mg

Higher than 55% of 1,337 products listing bromelain (median 50 mg).

Quercetin100 mgQuercetin in Pycnogenol Supreme against 1,548 products100 mg per serving; the middle half of products list 26.5 mg to 250 mg, the median 100 mg.100 mg

40% of 1,548 products listing quercetin give more (median 100 mg).

Ginkgo Leaf Extractas Ginkgo Flavone Glycosides, Terpene Lactones24% Flavone glycosides, 6% terpene lactones60 mgGinkgo in Pycnogenol Supreme against 1,339 products60 mg per serving; the middle half of products list 30 mg to 120 mg, the median 60 mg.60 mg

45% of 1,339 products listing ginkgo give more (median 60 mg).

Rutin60 mgRutin in Pycnogenol Supreme against 1,232 products60 mg per serving; the middle half of products list 10 mg to 50 mg, the median 25 mg.60 mg

Higher than 81% of 1,232 products listing rutin (median 25 mg).

Pycnogenolas French Maritime Pine Bark Extract65% Procyanidins50 mgMaritime Pine in Pycnogenol Supreme against 215 products50 mg per serving; the middle half of products list 25 mg to 100 mg, the median 50 mg.50 mg

38% of 215 products listing maritime pine give more (median 50 mg).

Silymarinas Milk Thistle seed extract50 mgSilymarin in Pycnogenol Supreme against 208 products50 mg per serving; the middle half of products list 63.75 mg to 203 mg, the median 116 mg.50 mg

81% of 208 products listing silymarin give more (median 116 mg).

Hawthorn Berry Extract50 mgHawthorn in Pycnogenol Supreme against 589 products50 mg per serving; the middle half of products list 75 mg to 400 mg, the median 200 mg.50 mg

78% of 589 products listing hawthorn give more (median 200 mg).

Citrus Bioflavonoid Complex50 mgFlavonoid in Pycnogenol Supreme against 2,343 products50 mg per serving; the middle half of products list 25 mg to 100 mg, the median 50 mg.50 mg

46% of 2,343 products listing flavonoid give more (median 50 mg).

Astragalus root extract50 mgAstragalus in Pycnogenol Supreme against 604 products50 mg per serving; the middle half of products list 50 mg to 405 mg, the median 132.5 mg.50 mg

73% of 604 products listing astragalus give more (median 132.5 mg).

Cranberry50 mgCranberry in Pycnogenol Supreme against 1,064 products50 mg per serving; the middle half of products list 97.5 mg to 500 mg, the median 250 mg.50 mg

80% of 1,064 products listing cranberry give more (median 250 mg).

Sweet Cherry Fruit Extract50 mgSweet Cherry in Pycnogenol Supreme against 43 products50 mg per serving; the middle half of products list 50 mg to 500 mg, the median 200 mg.50 mg

67% of 43 products listing sweet cherry give more (median 200 mg).

Holy Basil leaf extract50 mgHoly Basil in Pycnogenol Supreme against 387 products50 mg per serving; the middle half of products list 50 mg to 400 mg, the median 129 mg.50 mg

74% of 387 products listing holy basil give more (median 129 mg).

Olive Leaf Extractas Oleuropein10% oleuropein40 mgOlive in Pycnogenol Supreme against 822 products40 mg per serving; the middle half of products list 30 mg to 300 mg, the median 100 mg.40 mg

70% of 822 products listing olive give more (median 100 mg).

Lycium fruit extract40 mgGoji in Pycnogenol Supreme against 228 products40 mg per serving; the middle half of products list 60 mg to 600 mg, the median 190 mg.40 mg

83% of 228 products listing goji give more (median 190 mg).

Strawberry40 mgStrawberry in Pycnogenol Supreme against 85 products40 mg per serving; the middle half of products list 100 mg to 450 mg, the median 250 mg.40 mg

82% of 85 products listing strawberry give more (median 250 mg).

Acai fruit extract40 mgAcai in Pycnogenol Supreme against 433 products40 mg per serving; the middle half of products list 62.5 mg to 600 mg, the median 300 mg.40 mg

87% of 433 products listing acai give more (median 300 mg).

AmlaOrganic40 mgIndian Gooseberry in Pycnogenol Supreme against 327 products40 mg per serving; the middle half of products list 50 mg to 500 mg, the median 167 mg.40 mg

81% of 327 products listing indian gooseberry give more (median 167 mg).

Pomegranate fruit extract20 mgPomegranate in Pycnogenol Supreme against 860 products20 mg per serving; the middle half of products list 12.5 mg to 250 mg, the median 70.5 mg.20 mg

72% of 860 products listing pomegranate give more (median 70.5 mg).

Elderberry fruit extract20 mgEuropean Elder in Pycnogenol Supreme against 920 products20 mg per serving; the middle half of products list 50 mg to 400 mg, the median 150 mg.20 mg

93% of 920 products listing european elder give more (median 150 mg).

Mangosteen fruit rind extract10 mgMangosteen in Pycnogenol Supreme against 138 products10 mg per serving; the middle half of products list 40 mg to 500 mg, the median 250 mg.10 mg

92% of 138 products listing mangosteen give more (median 250 mg).

Raspberry leaf extract10 mgRaspberry in Pycnogenol Supreme against 110 products10 mg per serving; the middle half of products list 25 mg to 250 mg, the median 85 mg.10 mg

86% of 110 products listing raspberry give more (median 85 mg).

Bioperineas Black Pepper Fruit Extract6 mgBlack Pepper in Pycnogenol Supreme against 2,363 products6 mg per serving; the middle half of products list 5 mg to 10 mg, the median 5 mg.6 mg

Higher than 68% of 2,363 products listing black pepper (median 5 mg).

Bilberry Fruit Extractas Anthocyanins5 mgBilberry in Pycnogenol Supreme against 896 products5 mg per serving; the middle half of products list 20 mg to 100 mg, the median 50 mg.5 mg

94% of 896 products listing bilberry give more (median 50 mg).

Source: NIH ODS Dietary Supplement Label Database, label 275384 (entered January 23, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 93% of the 920 products that print an amount of european elder list more than its 20 mg of elderberry fruit extract (filed by NIH under european elder) (median 150 mg).
  • 92% of the 138 products that print an amount of mangosteen list more than its 10 mg of mangosteen (median 250 mg).
  • 86% of the 110 products that print an amount of raspberry list more than its 10 mg of raspberry (median 85 mg).
  • 94% of the 896 products that print an amount of bilberry list more than its 5 mg of bilberry (median 50 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Pycnogenol Supreme's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: 2 tablets daily.
Warnings
Contains soy.
Warning: Do not use if you are pregnant, may become pregnant, breastfeeding, or taking anticoagulant drugs such as heparin or warfarin (Coumadin). May interfere with the absorption of iron; if you are anemic, take between meals. If you are taking any prescription drug, consult a physician before using this product.
Do not use if either tamper-evident seal is broken or missing.
Keep out of the reach of children.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 275384.

What else is on the label?

Other ingredients: silicified Microcrystalline Cellulose, Stearic Acid, modified Cellulose Gum, Silica.

How many labels does Pycnogenol Supreme have?

2 labels are on file under this name since October 24, 2022: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 275384 (current) Entered January 23, 2023 · on the market · 60 tablets · UPC 0 21078 02220 6
  2. Label 275381 Entered October 24, 2022 · on the market · 30 tablets · UPC 0 21078 02219 0

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Source Naturals, Inc. (distributor), Santa Cruz, CA. All Source Naturals products.

Where next?