PlainVitamins

Ostera

by Metagenics · tablet or pill · 60 tablets

  • On the market (NIH)
  • UPC 7 55571 91876 5
  • DSLD label 295850
  • Serving 1 tablet
  • 60 servings

Ostera by Metagenics lists 4 ingredients, 4 with an amount per serving of 1 tablet, such as 12.5 mcg (500 IU) of vitamin D, 500 mcg of vitamin K, 370 mg of reduced iso-alpha acids complex and 90 mg of berberine hydrochloride. Its current label entered the NIH Dietary Supplement Label Database on August 23, 2023.

What is in Ostera?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Ostera: Supplement Facts rows against the market (DSLD label 295850, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Das Cholecalciferol500 IU12.5 mcg (500 IU)63%Vitamin D in Ostera against 14,175 products12.5 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg12.5 mcg

53% of 14,175 products listing vitamin D give more (median 15 mcg). Per day at the most servings: 25 mcg.

Vitamin Kas PhytonadioneUSP500 mcg417%Vitamin K in Ostera against 4,607 products500 mcg per serving; the middle half of products list 35 mcg to 100 mcg, the median 80 mcg.DV 120 mcg500 mcg

Higher than 95% of 4,607 products listing vitamin K (median 80 mcg). Per day at the most servings: 1,000 mcg.

Reduced Iso-Alpha Acids Complexas Hops extract370 mg
Berberine Hydrochlorideas Phellodendron amurense bark extract90 mgBerberine in Ostera against 419 products90 mg per serving; the middle half of products list 131.5 mg to 500 mg, the median 400 mg.90 mg

84% of 419 products listing berberine give more (median 400 mg). Per day at the most servings: 180 mg.

Source: NIH ODS Dietary Supplement Label Database, label 295850 (entered August 23, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 500 mcg of vitamin K is higher than 95% of the 4,607 vitamin K products that print an amount; 160 list more.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Ostera's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommended for use with Bone Builder - an advanced bioactive formulation for bone mineralization support.
Directions: Take one tablet twice daily, or as directed by your healthcare practitioner.
Warnings
Warning: Do not use if pregnant, nursing, or taking cyclosporine. Caution: If taking medications consult your healthcare practitioner before use.
Keep out of the reach of children.
Practitioner exclusive
Allergens and what it does not contain
This product is non-GMO and gluten-free.
Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)
Storage
Storage: Keep tightly closed in a cool, dry place.

Source: label statements in DSLD label 295850.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Stearic Acid, Croscarmellose Sodium, Hypromellose, Medium Chain Triglyceride, Hydroxypropyl Cellulose, Calcium Silicate, Silica.

How many labels does Ostera have?

5 labels are on file under this name since November 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 295850 (current) Entered August 23, 2023 · on the market · 60 tablets · UPC 7 55571 91876 5
  2. Label 265255 Entered May 19, 2022 · off the market September 7, 2022 · 60 tablets · UPC 7 55571 91876 5
  3. Label 216304 Entered March 24, 2020 · off the market October 1, 2021 · 60 tablets · UPC 7 55571 91876 5
  4. Label 209676 Entered December 22, 2019 · off the market December 27, 2019 · 60 tablets
  5. Label 27620 Entered November 25, 2013 · off the market July 3, 2019 · 60 tablets · UPC 7 55571 91876 5

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Metagenics (manufacturer), Gig Harbor, WA. All Metagenics products.

Where next?