SAMe
by Ortho Molecular Products · capsule · 60 capsules
- On the market (NIH)
- UPC 6 15033 01513 8
- DSLD label 174230
- Serving 1 to 2 capsules; amounts per 2 capsules
- 30 servings
SAMe by Ortho Molecular Products lists 2 ingredients, 2 with an amount per serving of 2 capsules, such as 400 mcg of folate and 400 mg of SAMe. Its current label entered the NIH Dietary Supplement Label Database on February 23, 2018.
What is in SAMe?
Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Folateas Glucosamine Salt, Quatrefolic (6S)-5-Methyltetrahydrofolic AcidFolate (Form: as Quatrefolic (6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt) | 400 mcg | 100% | 24% of 7,022 products listing folate give more (median 400 mcg). Per day at the most servings: 800 mcg. |
| SAMeas S-Adenosyl-L-Methionine Disulfate P-ToluenesulfonateSAMe (Form: as S-Adenosyl-L-Methionine Disulfate P-Toluensulfonate) | 400 mg | Higher than 53% of 163 products listing SAMe (median 200 mg). Per day at the most servings: 800 mg. |
Source: NIH ODS Dietary Supplement Label Database, label 174230 (entered February 23, 2018), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.
The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
The products whose ingredient lists overlap most with SAMe's, rare ingredients counting for more.
- BlisphoraMetagenics 2 shared, 81% alike
- SAM-e 200 mgGNC · off the market 1 shared, 74% alike
- SAM-e 400 mgGNC · off the market 1 shared, 74% alike
- SAMe 200 mgBronson Laboratories 1 shared, 74% alike
- SAM-e 200 mgVitabase 1 shared, 74% alike
- SAMe Iso Active 200 mgNatural Factors · off the market 1 shared, 74% alike
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Suggested Use: 1-2 capsules two times per day or as recommended by your health care professional.
- Warnings
- Do not consume this product if you are pregnant or nursing. Consult your physician for further information.
- As with all dietary supplements, some individuals may not tolerate or may be allergic to the ingredients used. Please read the ingredient panel carefully prior to ingestion. Cease taking this product and consult your physician if you have negative reactions upon ingestion.
- Caution: This product contains a desiccant. For best results, keep the desiccant in the bottle until all contents are consumed. Do not eat desiccant.
- Keep out of reach of children.
- This product was sealed for your protection. Do not use if outer logoed neck seal or inner-seal is missing or damaged.
- Warning: This product should not be taken with any anti-depressant drugs (MAO Inhibitors, bicyclic, tricyclic, Fluoxetine, etc.) unless under close supervision of your health care professional.
- Do not accept if label shows signs of tampering
- Allergens and what it does not contain
- Formulated To Be Free Of Allergens Derived From: Gluten, corn, yeast, artificial colors and flavors.
- Storage
- For best results, keep the desiccant in the bottle until all contents are consumed.
- Keep container tightly closed. Refrigerate after opening.
Source: label statements in DSLD label 174230.
What else is on the label?
Other ingredients: natural Vegetable Capsules, Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Vcaps.
How many labels does SAMe have?
One label is on file, entered on February 23, 2018.
- Label 174230 (current) Entered February 23, 2018 · on the market · 60 capsules · UPC 6 15033 01513 8
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Ortho Molecular Products, Inc. (manufacturer), Woodstock, IL. All Ortho Molecular Products products.