PlainVitamins

Methylation Support

by Akasha Naturals · capsule · 120 vegetarian capsules

  • On the market (NIH)
  • UPC 7 55571 94885 4
  • DSLD label 313116
  • Serving 2 capsules
  • 60 servings

Methylation Support by Akasha Naturals lists 9 ingredients, 9 with an amount per serving of 2 capsules, such as 1.6 mg of riboflavin, 25 mg of vitamin B6, 1,330 mcg DFE of metafolin and 1,000 mcg of vitamin B12. Its current label entered the NIH Dietary Supplement Label Database on October 24, 2024.

What is in Methylation Support?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Methylation Support: Supplement Facts rows against the market (DSLD label 313116, January 2026 release)
IngredientAmount% DVAmong products listing it
Riboflavin1.6 mg123%Riboflavin in Methylation Support against 9,824 products1.6 mg per serving; the middle half of products list 1.7 mg to 25 mg, the median 4 mg.DV 1.3 mg1.6 mg

78% of 9,824 products listing riboflavin give more (median 4 mg).

Vitamin B6as Pyridoxine Hydrochloride25 mg1,471%Vitamin B6 in Methylation Support against 15,277 products25 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg25 mg

Higher than 76% of 15,277 products listing vitamin B6 (median 6 mg).

Metafolinas FolateAs Metafolin. Metafolin is a registered trademark of Merck KGaA, Darmstadt Germany1,330 mcg DFE333%
Vitamin B12as Methylcobalamin1,000 mcg41,667%Vitamin B12 in Methylation Support against 14,425 products1,000 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg1,000 mcg

Higher than 89% of 14,425 products listing vitamin B12 (median 36 mcg).

Zincas Zinc Citrate1.5 mg14%Zinc in Methylation Support against 13,186 products1.5 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg1.5 mg

94% of 13,186 products listing zinc give more (median 11 mg).

Manganeseas Manganese Citrate0.4 mg17%Manganese in Methylation Support against 7,016 products0.4 mg per serving; the middle half of products list 1 mg to 3.92 mg, the median 2 mg.DV 2.3 mgUL 11 mg0.4 mg

91% of 7,016 products listing manganese give more (median 2 mg).

Molybdenumas Molybdenum Glycinate15 mcg33%Molybdenum in Methylation Support against 4,390 products15 mcg per serving; the middle half of products list 25 mcg to 75 mcg, the median 50 mcg.DV 45 mcgUL 2,000 mcg15 mcg

87% of 4,390 products listing molybdenum give more (median 50 mcg).

N-Acetyl-L-Cysteine600 mgN-Acetyl Cysteine in Methylation Support against 1,259 products600 mg per serving; the middle half of products list 55 mg to 500 mg, the median 150 mg.600 mg

Higher than 80% of 1,259 products listing N-acetyl cysteine (median 150 mg).

Betaine Hydrochloride500 mgBetaine Hydrochloride in Methylation Support against 914 products500 mg per serving; the middle half of products list 25 mg to 178 mg, the median 50 mg.500 mg

Higher than 89% of 914 products listing betaine hydrochloride (median 50 mg).

Source: NIH ODS Dietary Supplement Label Database, label 313116 (entered October 24, 2024), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 94% of the 13,186 products that print an amount of zinc list more than its 1.5 mg of zinc (median 11 mg).
  • 91% of the 7,016 products that print an amount of manganese list more than its 0.4 mg of manganese (median 2 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

1 product lists the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take 2 capsules once daily, or as directed by your healthcare practitioner.
Warnings
Caution: if pregnant or nursing, or taking medications, please consult your healthcare practitioner before use.
Keep out of the reach of children.
To report adverse events call 866-649-4334.
Allergens and what it does not contain
This product is non-GMO and gluten-free.
Storage
Storage: Keep tightly closed in a cool, dry place.

Source: label statements in DSLD label 313116.

What else is on the label?

Other ingredients: Hydroxypropyl Methylcellulose, silicified Microcrystalline Celluloses, Stearic Acid, Magnesium Stearate, Silica.

How many labels does Methylation Support have?

One label is on file, entered on October 24, 2024.

  1. Label 313116 (current) Entered October 24, 2024 · on the market · 120 vegetarian capsules · UPC 7 55571 94885 4

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Akasha Center for Integrative Medicine, LLC (distributor), Santa Monica, CA. All Akasha Naturals products.

Where next?