Methylation Protect
by Adaptogen Research · capsule · 120 vegetarian capsules
- On the market (NIH)
- UPC 7 22537 49795 4
- DSLD label 307154
- Serving 1 capsule
- 120 servings
Methylation Protect by Adaptogen Research lists 7 ingredients, 7 with an amount per serving of 1 capsule, such as 25 mg of riboflavin, 10 mg of vitamin B6, 3,400 mcg of folate and 1,000 mcg of vitamin B12. Its current label entered the NIH Dietary Supplement Label Database on April 23, 2024.
What is in Methylation Protect?
Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Riboflavinas Riboflavin 5-Phosphate Sodium | 25 mg | 1,923% | Higher than 75% of 9,824 products listing riboflavin (median 4 mg). Per day at the most servings: 50 mg. |
| Vitamin B6as Pyridoxal 5-Phosphate | 10 mg | 588% | Higher than 55% of 15,277 products listing vitamin B6 (median 6 mg). Per day at the most servings: 20 mg. |
| Folate | 3,400 mcg | 850% | Higher than 99% of 7,022 products listing folate (median 400 mcg). Per day at the most servings: 6,800 mcg. |
| Calcium Folinate | 1,700 mcg DFE | ||
| Quatrefolicas (6S)-5-Methyltetrahydrofolic Acid Glucosamine Salt | 1,700 mcg DFE | ||
| Vitamin B12as Methylcobalamin | 1,000 mcg | 41,667% | Higher than 89% of 14,425 products listing vitamin B12 (median 36 mcg). Per day at the most servings: 2,000 mcg. |
| Betaine Anhydrousas Trimethylglycine | 500 mg | 84% of 860 products listing betaine anhydrous give more (median 1.5 g). Per day at the most servings: 1 g. |
Source: NIH ODS Dietary Supplement Label Database, label 307154 (entered April 23, 2024), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:
- Its 3,400 mcg of folate is higher than 99% of the 7,022 folate products that print an amount; 93 list more.
The NIH database records 1 to 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
3 products list the very same ingredients; the nearest amounts come first.
- Methyl ShieldNHC Natural Healthy Concepts same ingredients
- Methyl ProtectXYMOGEN same ingredients
- Methyl ShieldNatural Healthy Concepts same ingredients
- Prena1 Chew With QuatrefolicBocaGreenMD 5 shared, 64% alike
- RediChew RxvitaMedMD 5 shared, 64% alike
- Methyl-Guard PlusThorne Research · off the market 5 shared, 62% alike
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Directions: take one capsule one to two times daily, or as directed by your healthcare professional.
- Warnings
- Consult your healthcare professional prior to use. Do not use if tamper seal is damaged.
- Report any adverse reaction on adaptogenresearch.com
- Professional use only
- Individuals taking medication should discuss potential interactions with their healthcare professional.
- Storage: Keep closed in a cool, dry place out of reach of children.
- Allergens and what it does not contain
- Formulated to exclude: wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.
- Made with non-GMO ingredients Does not contain gluten NAC Free
Source: label statements in DSLD label 307154.
What else is on the label?
Other ingredients: Hypromellose, Water, Stearic Acid, Microcrystalline Cellulose, Silica, Magnesium Stearate, Medium Chain Triglyceride Oil.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Guaranteed GMP compliant products.
How many labels does Methylation Protect have?
2 labels are on file under this name since May 22, 2021: other sizes, label designs and reformulations. The current one leads this page.
- Label 307154 (current) Entered April 23, 2024 · on the market · 120 vegetarian capsules · UPC 7 22537 49795 4
- Label 247132 Entered May 22, 2021 · off the market March 10, 2023 · 120 vegetarian capsules · UPC 0 612524 953306
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Adaptogen Research (distributor), Newark, DE. All Adaptogen Research products.