High Potency Optimized Folate 8500 mcg DFE

by Life Extension · tablet or pill · 30 vegetarian tablets

  • On the market (NIH)
  • UPC 7 37870 19133 9
  • DSLD label 232089
  • Serving 1 vegetarian tablet

High Potency Optimized Folate 8500 mcg DFE by Life Extension lists one ingredient: 8,500 mcg DFE of folate per serving of 1 vegetarian tablet. Its current label entered the NIH Dietary Supplement Label Database on August 23, 2020.

What is in High Potency Optimized Folate 8500 mcg DFE?

Each row as the label prints it, per serving of 1 vegetarian tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

High Potency Optimized Folate 8500 mcg DFE: Supplement Facts rows against the market (DSLD label 232089, January 2026 release)
IngredientAmount% DVAmong products listing it
Folateas (6S)-5-Methyltetrahydrofolate Calcium SaltFolate (Form: as (6S)-5-Methyltetrahydrofolate, Calcium Salt)8,500 mcg DFE2,125%

Source: NIH ODS Dietary Supplement Label Database, label 232089 (entered August 23, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) tablet daily with food, or as recommended by a healthcare practitioner.
Warnings
Caution: Do not use this product if treated with methotrexate, fluorouracil, phenytoin, phenobarbital, primidone, or levodopa prior to consultation with your personal physician.
Warnings: Keep out of reach of children.
Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Allergens and what it does not contain
Gluten free Non GMO LE Certified
Storage
Store tightly closed in a cool, dry place.

Source: label statements in DSLD label 232089.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Stearic Acid, Croscarmellose Sodium, Silica, Vegetable Stearate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Non GMO LE Certified.

How many labels does High Potency Optimized Folate 8500 mcg DFE have?

One label is on file, entered on August 23, 2020.

  1. Label 232089 (current) Entered August 23, 2020 · on the market · 30 vegetarian tablets · UPC 7 37870 19133 9

DSLD also links this label to: High Potency Optimized Folate (image difference, same product), High Potency Optimized Folate (image difference, same product), High Potency Optimized Folate 5000 mcg (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Quality Supplements and Vitamins, Inc. (distributor), Ft. Lauderdale, FL. All Life Extension products.

Where next?