PlainVitamins

EstroPause

by Irwin Naturals · softgel capsule · 80 liquid softgels

  • On the market (NIH)
  • UPC 7 10363 26244 0
  • DSLD label 292070
  • Serving 2 to 4 liquid softgels; amounts per 4 liquid softgels
  • 20 servings

EstroPause by Irwin Naturals lists 16 ingredients, 14 with an amount per serving of 4 liquid softgels, such as 500 mg of calcium, 0.6 mg of iron, 200 mg of magnesium and 2,158 mg of fish oil; 2 sit inside a blend without their own amounts, beside 6 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on June 22, 2023.

What is in EstroPause?

Each row as the label prints it, per serving of 4 liquid softgels. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

EstroPause: Supplement Facts rows against the market (DSLD label 292070, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories35 Calories
Total Fat2 g3%Fat (unspecified) in EstroPause against 11,965 products2 g per serving; the middle half of products list 1 g to 2.5 g, the median 1.5 g.2 g

Higher than 56% of 11,965 products listing fat (unspecified) (median 1.5 g).

Saturated Fat0.5 g3%Saturated fat in EstroPause against 5,234 products0.5 g per serving; the middle half of products list 0.5 g to 1.5 g, the median 1 g.0.5 g

66% of 5,234 products listing saturated fat give more (median 1 g).

Cholesterol10 mg3%Cholesterol in EstroPause against 5,275 products10 mg per serving; the middle half of products list 5 mg to 45 mg, the median 15 mg.10 mg

56% of 5,275 products listing cholesterol give more (median 15 mg).

Total Carbohydrates2 g1%Carbohydrate in EstroPause against 21,979 products2 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.2 g

58% of 21,979 products listing carbohydrate give more (median 3 g).

Protein2 gProtein in EstroPause against 8,985 products2 g per serving; the middle half of products list 2 g to 24 g, the median 16 g.2 g

70% of 8,985 products listing protein give more (median 16 g).

Calciumas Calcium Carbonate, Calcium Citrate500 mg38%Calcium in EstroPause against 17,831 products500 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg500 mg

Higher than 85% of 17,831 products listing calcium (median 115 mg).

Iron0.6 mg3%Iron in EstroPause against 6,910 products0.6 mg per serving; the middle half of products list 1.2 mg to 18 mg, the median 5 mg.DV 18 mgUL 45 mg0.6 mg

88% of 6,910 products listing iron give more (median 5 mg).

Magnesiumas Magnesium Citrate, Magnesium Oxide200 mg48%Magnesium in EstroPause against 14,003 products200 mg per serving; the middle half of products list 30 mg to 200 mg, the median 86 mg.UL 350 mgDV 420 mg200 mg

Higher than 75% of 14,003 products listing magnesium (median 86 mg).

Sodium15 mg1%Sodium in EstroPause against 14,514 products15 mg per serving; the middle half of products list 15 mg to 142 mg, the median 55 mg.15 mg

72% of 14,514 products listing sodium give more (median 55 mg).

Fish Oilas Fish2,158 mgFish Oil in EstroPause against 1,990 products2.16 g per serving; the middle half of products list 1 g to 2 g, the median 1.2 g.2.16 g

Higher than 84% of 1,990 products listing fish oil (median 1.2 g).

Omega-3 Fatty Acids30%647 mgOmega-3 in EstroPause against 2,714 products647 mg per serving; the middle half of products list 230 mg to 1,000 mg, the median 500 mg.647 mg

Higher than 60% of 2,714 products listing omega-3 (median 500 mg).

St. John's Wort Extract300 mgSt. John's Wort in EstroPause against 338 products300 mg per serving; the middle half of products list 250 mg to 450 mg, the median 300 mg.300 mg

37% of 338 products listing St. John's wort give more (median 300 mg).

Hypericin0.3%0.9 mgHypericin in EstroPause against 33 products900 mcg per serving; the middle half of products list 900 mcg to 1,800 mcg, the median 900 mcg.900 mcg

45% of 33 products listing hypericin give more (median 900 mcg).

Soy Isoflavones100 mgIsoflavones in EstroPause against 290 products100 mg per serving; the middle half of products list 25 mg to 80 mg, the median 50 mg.100 mg

Higher than 79% of 290 products listing isoflavones (median 50 mg).

Total Isoflavones5%5 mg
Black Cohosh root extract80 mgBlack Cohosh in EstroPause against 431 products80 mg per serving; the middle half of products list 40 mg to 160 mg, the median 80 mg.80 mg

46% of 431 products listing black cohosh give more (median 80 mg).

Triterpenoid Saponins2.5%2 mg
Red Clover, Powder40 mgRed Clover in EstroPause against 279 products40 mg per serving; the middle half of products list 50 mg to 400 mg, the median 150 mg.40 mg

83% of 279 products listing red clover give more (median 150 mg).

Asian Ginseng root extract31 mgOriental Ginseng in EstroPause against 706 products31 mg per serving; the middle half of products list 30 mg to 200 mg, the median 90 mg.31 mg

74% of 706 products listing oriental ginseng give more (median 90 mg).

Chasteberry Fruit Extract10:120 mgChastetree in EstroPause against 386 products20 mg per serving; the middle half of products list 50 mg to 240 mg, the median 100 mg.20 mg

90% of 386 products listing chastetree give more (median 100 mg).

BioPerine Complex6 mg
BioPerineas Black Pepper Fruit Extract95% piperinein the blend, no amount given
Ginger Rhizome Extractas Gingerols5% gingerolsin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 292070 (entered June 22, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 90% of the 386 products that print an amount of chastetree list more than its 20 mg of chasteberry fruit extract (filed by NIH under chastetree) (median 100 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: (Adult) take two (2) to four (4) liquid soft-gels a day with meals and a full glass (8oz) of water. May be taken all at once or divided throughout the day.
Warnings
Usage warnings: Do not use if safety seal is broken.
St. Johns Wort can interact with medications, such as antidepressants, heart medications, blood thinners, immunosuppressants, and other medications.
Avoid excessive sun exposure as use of this product may cause your skin to be extra sensitive to UV sources. This product contains an ingredient that may affect blood sugar.
Check with your doctor before using this product if you are using medication or have any medical conditions, including heart disease and/or high/low blood pressure. Do not use if you may become pregnant, are pregnant, nursing, or taking contraceptives.
Do not exceed 90 days of continuous use of this product without a two (2) week break. Do not exceed recommended daily intake.
Not intended for use by persons under 18. Keep out of reach of children.
Contains: Fish (anchovy, sardine), soy
Allergens and what it does not contain
No preservatives added.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 292070.

What else is on the label?

Other ingredients: Gelatin, Water, Purified, Glycerin, Soy Lecithin, Titanium Dioxide, Beeswax, Lycopene, Maltodextrin.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Quality Tested Guaranteed Pass.

How many labels does EstroPause have?

3 labels are on file under this name since April 24, 2015: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 292070 (current) Entered June 22, 2023 · on the market · 80 liquid softgels · UPC 7 10363 26244 0
  2. Label 56507 Entered April 22, 2016 · on the market · 80 liquid softgels · UPC 7 10363 26244 0
  3. Label 44663 Entered April 24, 2015 · off the market June 17, 2015 · 80 liquid softgels · UPC 7 10363 26244 0

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Irwin Naturals (manufacturer, distributor), Los Angeles, CA. All Irwin Naturals products.

Where next?