CholestOff Plus

by Nature Made · softgel capsule · 100 softgels

  • On the market (NIH)
  • DSLD label 270710
  • Serving 2 softgels
  • 50 servings

CholestOff Plus by Nature Made lists 3 ingredients, 1 with an amount per serving of 2 softgels, such as 900 mg of plant sterols and plant stanols; 2 sit inside a blend without their own amounts, beside 2 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on June 16, 2022.

What is in CholestOff Plus?

Each row as the label prints it, per serving of 2 softgels. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

CholestOff Plus: Supplement Facts rows against the market (DSLD label 270710, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories15 Calories
Total Fat1.5 g2%Fat (unspecified) in CholestOff Plus against 11,965 products1.5 g per serving; the middle half of products list 1 g to 2.5 g, the median 1.5 g.1.5 g

44% of 11,965 products listing fat (unspecified) give more (median 1.5 g). Per day at the most servings: 3 g.

Proteinless than 1 g
Plant Sterols and Plant Stanolsas EstersSterols/stanols are esterified with sunflower oil fatty acids.900 mg
Plant Sterolsas Estersno amount given
Plant Stanolsas Estersno amount given

Source: NIH ODS Dietary Supplement Label Database, label 270710 (entered June 16, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 2 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with CholestOff Plus's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: Adults, take 2 softgels twice daily with water at your two largest meals.
Warnings
Store tightly closed, in a cool, dry place, out of reach of children.
Do not use if imprinted seal under cap is broken or missing.
Caution: If you are pregnant, nursing, or taking any medications, consult your physician before use.
Sterols/Stanols are esterified with sunflower oil fatty acids.
Allergens and what it does not contain
No synthetic dyes - colors derived from natural sources No artificial flavors No preservatives Gluten free

Source: label statements in DSLD label 270710.

What else is on the label?

Other ingredients: Plant Sterols, Plant Stanols, Sunflower Oil Esters, Gelatin, Glycerin, Medium Chain Triglyceride, Rapeseed Lecithin, Water, Colors added.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): USP Dietary Supplement Verified. Listed with: USP Verified mark (a seal is the label's claim; the certifier's own list confirms it).

How many labels does CholestOff Plus have?

3 labels are on file under this name since September 21, 2018: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 270710 (current) Entered June 16, 2022 · on the market · 100 softgels
  2. Label 179818 Entered September 21, 2018 · on the market · 200 softgels · UPC 0 31604 02789 6
  3. Label 179813 Entered September 21, 2018 · on the market · 100 softgels · UPC 0 31604 02788 9

DSLD also links this label to: CholestOff Plus 450 mg (image difference, same product), CholestOff Plus 450 mg (package size difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature Made Nutritional Products (distributor), West Hills, CA. All Nature Made products.

Where next?