CholestOff Plus 450 mg

by Nature Made · softgel capsule · 100 softgels

  • On the market (NIH)
  • DSLD label 71081
  • Serving 2 softgels
  • 50 servings

CholestOff Plus 450 mg by Nature Made lists 3 ingredients, 1 with an amount per serving of 2 softgels, such as 900 mg of plant sterols and plant stanols; 2 sit inside a blend without their own amounts, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on February 24, 2017.

What is in CholestOff Plus 450 mg?

Each row as the label prints it, per serving of 2 softgels. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

CholestOff Plus 450 mg: Supplement Facts rows against the market (DSLD label 71081, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories10 Calories
Calories from Fat10 Calories
Total Fat1 g2%Fat (unspecified) in CholestOff Plus 450 mg against 11,965 products1 g per serving; the middle half of products list 1 g to 2.5 g, the median 1.5 g.1 g

56% of 11,965 products listing fat (unspecified) give more (median 1.5 g). Per day at the most servings: 2 g.

Plant Sterols and Plant Stanolsas EstersSterols/stanols are esterified with sunflower oil fatty acids.900 mg
Plant Sterolsas Estersno amount given
Plant Stanolsas Estersno amount given

Source: NIH ODS Dietary Supplement Label Database, label 71081 (entered February 24, 2017), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 2 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with CholestOff Plus 450 mg's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: Take two softgels two times daily with meals.
Warnings
Caution: Not for use by children or pregnant or lactating women. Check with your physician before using CholesOff Plus if you are currently using medication to lower your cholesterol.
Caution: Not for use by children or pregnant or lactating women.
Store in a cool, dry place out of reach of children.
Do not use if imprinted seal under cap is broken or missing.
Allergens and what it does not contain
- No synthetic dyes No artificial flavors - No preservatives No yeast or starch - Gluten free
Storage
Keep bottle tightly closed. Store in a cool, dry place out of reach of children.

Source: label statements in DSLD label 71081.

What else is on the label?

Other ingredients: Plant Sterols, Plant Stanols, Sunflower Oil Esters, Gelatin, Glycerin, Medium Chain Triglycerides, Soy Lecithin, Water, Colors added.

How many labels does CholestOff Plus 450 mg have?

One label is on file, entered on February 24, 2017.

  1. Label 71081 (current) Entered February 24, 2017 · on the market · 100 softgels

DSLD also links this label to: CholestOff Plus (image difference, same product), CholestOff Plus (package size difference, same product), CholestOff Plus (package size difference, same product), CholestOff Plus (image difference, same product), CholestOff Plus (package size difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature Made Nutritional Products (distributor), Mission Hills, CA, U.S.A.. All Nature Made products.

Where next?