PlainVitamins

Arthri-Flex Advantage + Vitamin D3

by 21st Century · tablet or pill · 120 coated tablets

  • On the market (NIH)
  • UPC 7 40985 22623 0
  • DSLD label 326310
  • Serving 2 tablets; amounts per 4 tablets
  • 30 servings

Arthri-Flex Advantage + Vitamin D3 by 21st Century lists 17 ingredients, 11 with an amount per serving of 4 tablets, such as 100 mg of vitamin C, 50 mcg (2,000 IU) of vitamin D3, 200 mg of magnesium and 15 mg of zinc; 6 sit inside a blend without their own amounts, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on January 23, 2025.

What is in Arthri-Flex Advantage + Vitamin D3?

Each row as the label prints it, per serving of 4 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Arthri-Flex Advantage + Vitamin D3: Supplement Facts rows against the market (DSLD label 326310, January 2026 release)
IngredientAmount% DVAmong products listing it
Total Carbohydrates1 g1%Carbohydrate in Arthri-Flex Advantage + Vitamin D3 against 21,979 products1 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.1 g

74% of 21,979 products listing carbohydrate give more (median 3 g). Per day at the most servings: 2 g.

Vitamin Cas Calcium Ascorbate100 mg111%Vitamin C in Arthri-Flex Advantage + Vitamin D3 against 18,583 products100 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg100 mg

50% of 18,583 products listing vitamin C give more (median 100 mg). Per day at the most servings: 200 mg.

Vitamin D3as Cholecalciferol2,000 IU50 mcg (2,000 IU)250%Vitamin D in Arthri-Flex Advantage + Vitamin D3 against 14,175 products50 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg50 mcg

Higher than 81% of 14,175 products listing vitamin D (median 15 mcg). Per day at the most servings: 100 mcg.

Magnesiumas Magnesium Glycinate200 mg48%Magnesium in Arthri-Flex Advantage + Vitamin D3 against 14,003 products200 mg per serving; the middle half of products list 30 mg to 200 mg, the median 86 mg.UL 350 mgDV 420 mg200 mg

Higher than 75% of 14,003 products listing magnesium (median 86 mg). Per day at the most servings: 400 mg. 1.1 times the adult UL a day.

Zincas Zinc Glycinate15 mg136%Zinc in Arthri-Flex Advantage + Vitamin D3 against 13,186 products15 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg15 mg

Higher than 56% of 13,186 products listing zinc (median 11 mg). Per day at the most servings: 30 mg.

Copperas Copper Glycinate0.5 mg56%Copper in Arthri-Flex Advantage + Vitamin D3 against 6,468 products0.5 mg per serving; the middle half of products list 0.5 mg to 2 mg, the median 1 mg.DV 0.9 mgUL 10 mg0.5 mg

68% of 6,468 products listing copper give more (median 1 mg). Per day at the most servings: 1 mg.

Manganeseas Manganese Glycinate5 mg217%Manganese in Arthri-Flex Advantage + Vitamin D3 against 7,016 products5 mg per serving; the middle half of products list 1 mg to 3.92 mg, the median 2 mg.DV 2.3 mgUL 11 mg5 mg

Higher than 80% of 7,016 products listing manganese (median 2 mg). Per day at the most servings: 10 mg.

Molybdenumas Molybdenum Glycinate220 mcg489%Molybdenum in Arthri-Flex Advantage + Vitamin D3 against 4,390 products220 mcg per serving; the middle half of products list 25 mcg to 75 mcg, the median 50 mcg.DV 45 mcgUL 2,000 mcg220 mcg

Higher than 97% of 4,390 products listing molybdenum (median 50 mcg). Per day at the most servings: 440 mcg.

Potassiumas Potassium Chloride195 mg4%Potassium in Arthri-Flex Advantage + Vitamin D3 against 11,614 products195 mg per serving; the middle half of products list 50 mg to 190 mg, the median 99 mg.DV 4,700 mg195 mg

Higher than 76% of 11,614 products listing potassium (median 99 mg). Per day at the most servings: 390 mg.

Glucosamine Sulfateas Glucosamine Sulfate 2KCl1,500 mgGlucosamine Sulfate in Arthri-Flex Advantage + Vitamin D3 against 875 products1.5 g per serving; the middle half of products list 0.5 g to 1.5 g, the median 1 g.1.5 g

Higher than 64% of 875 products listing glucosamine sulfate (median 1 g). Per day at the most servings: 3 g.

Methylsulfonylmethane1,500 mgMethylsulfonylmethane in Arthri-Flex Advantage + Vitamin D3 against 1,454 products1,500 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.1,500 mg

Higher than 88% of 1,454 products listing methylsulfonylmethane (median 500 mg). Per day at the most servings: 3,000 mg.

Hyaluronic Acidas Sodium Hyaluronate80 mgHyaluronic acid in Arthri-Flex Advantage + Vitamin D3 against 900 products80 mg per serving; the middle half of products list 10 mg to 100 mg, the median 50 mg.80 mg

Higher than 62% of 900 products listing hyaluronic acid (median 50 mg). Per day at the most servings: 160 mg.

Proprietary Blend1,045 mg
Chicken Sternum Collagen Type IIas Chondroitin Sulfatepremium, naturally occurring chondroitin sulfatein the blend, no amount given
Hyaluronic Acidas Sodium Hyaluronatein the blend, no amount given
Boron Glycinatein the blend, no amount given

The label names the compound (Boron Glycinate); its amount is likely the compound's weight, not the boron it holds, so it is not placed among other products.

Boswellia serrata Resin Extractin the blend, no amount given
Grape Seed Extractas Vitis vinifera Seed Extractin the blend, no amount given
White Willow Bark Extractas Salix alba Bark Extractin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 326310 (entered January 23, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 2 servings a day, the most its directions give, the label lists 400 mg of magnesium, 1.1 times the adult Tolerable Upper Intake Level.
  • Its 220 mcg of molybdenum is higher than 97% of the 4,390 molybdenum products that print an amount; 119 list more.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Arthri-Flex Advantage + Vitamin D3's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As a dietary supplement, adults take four (4) tablets daily, two (2) in the morning and two (2) in teh afternoon, preferably with meals or as directed by a healthcare provider.
Warnings
Do not exceed recommended dosage.
Warning: Consult a healthcare provider prior to use if pregnant, nursing, taking medications, including blood thinners, have a medical condition or are planning a medical procedure.
Stop use and contact a physician if adverse reactions occur.
Keep out of reach of children.
Do not use if product appears to be tampered with or seal is broken.
Contains shellfish (shrimp, crab, lobster, crayfish).
Allergens and what it does not contain
No added yeast, soy, dairy or artificial flavors.
Bovine free
Storage
Store at room temperature.

Source: label statements in DSLD label 326310.

What else is on the label?

Other ingredients: Cellulose, Stearic Acid, Croscarmellose Sodium, Magnesium Silicate, Magnesium Stearate, Polyethylene Glycol, Polyplasdone, Polyvinyl Alcohol, Silicon Dioxide, Titanium Dioxide.

How many labels does Arthri-Flex Advantage + Vitamin D3 have?

7 labels are on file under this name since March 25, 2015: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 326310 (current) Entered January 23, 2025 · on the market · 120 coated tablets · UPC 7 40985 22623 0
  2. Label 258312 Entered December 18, 2021 · off the market July 18, 2023 · 120 coated tablets · UPC 7 40985 22623 0
  3. Label 207404 Entered September 24, 2019 · on the market · 180 coated tablets · UPC 7 40985 27066 0
  4. Label 205991 Entered August 23, 2019 · off the market August 6, 2021 · 120 coated tablets · UPC 7 40985 22623 0
  5. Label 65797 Entered October 22, 2016 · off the market March 14, 2019 · 120 coated tablets · UPC 7 40985 22623 0
  6. Label 43802 Entered March 25, 2015 · off the market June 28, 2019 · 180 coated tablets · UPC 7 40985 27066 0
  7. Label 43608 Entered March 25, 2015 · off the market June 15, 2016 · 120 coated tablets · UPC 7 40985 22623 0

DSLD also links this label to: Arthri-Flex Advantage + Vitamin D3 (package size difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names 21st Century HealthCare, Inc. (manufacturer), Tempe, AZ. All 21st Century products.

Where next?