PlainVitamins

Arthri-Flex Advantage + Vitamin D3

by 21st Century HealthCare · tablet or pill · 180 coated tablets

  • Off the market since August 2020 (NIH)
  • UPC 7 40985 27066 0
  • DSLD label 233355
  • Serving 2 tablets; amounts per 4 tablets
  • 45 servings

Arthri-Flex Advantage + Vitamin D3 by 21st Century HealthCare lists 16 ingredients, 10 with an amount per serving of 4 tablets, such as 100 mg of vitamin C, 200 mg of magnesium, 15 mg of zinc and 500 mcg of copper; 6 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on August 23, 2020.

What is in Arthri-Flex Advantage + Vitamin D3?

Each row as the label prints it, per serving of 4 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Arthri-Flex Advantage + Vitamin D3: Supplement Facts rows against the market (DSLD label 233355, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Cas Calcium AscorbateVitamin C (Form: as Calcium Ascorbate)100 mg167%Vitamin C in Arthri-Flex Advantage + Vitamin D3 against 18,583 products100 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg100 mg

50% of 18,583 products listing vitamin C give more (median 100 mg). Per day at the most servings: 200 mg.

Magnesiumas Magnesium GlycinateMagnesium (Form: as Magnesium Glycinate)200 mg50%Magnesium in Arthri-Flex Advantage + Vitamin D3 against 14,003 products200 mg per serving; the middle half of products list 30 mg to 200 mg, the median 86 mg.UL 350 mgDV 420 mg200 mg

Higher than 75% of 14,003 products listing magnesium (median 86 mg). Per day at the most servings: 400 mg. 1.1 times the adult UL a day.

Zincas Zinc GlycinateZinc (Form: as Zinc Glycinate)15 mg100%Zinc in Arthri-Flex Advantage + Vitamin D3 against 13,186 products15 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg15 mg

Higher than 56% of 13,186 products listing zinc (median 11 mg). Per day at the most servings: 30 mg.

Copperas Copper GlycinateCopper (Form: as Copper Glycinate)500 mcg25%Copper in Arthri-Flex Advantage + Vitamin D3 against 6,468 products0.5 mg per serving; the middle half of products list 0.5 mg to 2 mg, the median 1 mg.DV 0.9 mgUL 10 mg0.5 mg

68% of 6,468 products listing copper give more (median 1 mg). Per day at the most servings: 1 mg.

Vitamin D3as Cholecalciferol2,000 IU (50 mcg)500%Vitamin D in Arthri-Flex Advantage + Vitamin D3 against 14,175 products50 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg50 mcg

Higher than 81% of 14,175 products listing vitamin D (median 15 mcg). Per day at the most servings: 100 mcg.

Manganeseas Manganese GlycinateManganese (Form: as Manganese Glycinate)5 mg250%Manganese in Arthri-Flex Advantage + Vitamin D3 against 7,016 products5 mg per serving; the middle half of products list 1 mg to 3.92 mg, the median 2 mg.DV 2.3 mgUL 11 mg5 mg

Higher than 80% of 7,016 products listing manganese (median 2 mg). Per day at the most servings: 10 mg.

Molybdenumas Molybdenum GlycinateMolybdenum (Form: as Molybdenum Glycinate)220 mcg293%Molybdenum in Arthri-Flex Advantage + Vitamin D3 against 4,390 products220 mcg per serving; the middle half of products list 25 mcg to 75 mcg, the median 50 mcg.DV 45 mcgUL 2,000 mcg220 mcg

Higher than 97% of 4,390 products listing molybdenum (median 50 mcg). Per day at the most servings: 440 mcg.

Glucosamine Sulfate1,500 mgGlucosamine Sulfate in Arthri-Flex Advantage + Vitamin D3 against 875 products1.5 g per serving; the middle half of products list 0.5 g to 1.5 g, the median 1 g.1.5 g

Higher than 64% of 875 products listing glucosamine sulfate (median 1 g). Per day at the most servings: 3 g.

MSM1,500 mgMethylsulfonylmethane in Arthri-Flex Advantage + Vitamin D3 against 1,454 products1,500 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.1,500 mg

Higher than 88% of 1,454 products listing methylsulfonylmethane (median 500 mg). Per day at the most servings: 3,000 mg.

Hyaluronic Acidas Sodium HyaluronateHyaluronic Acid (Form: as Sodium Hyaluronate)80 mgHyaluronic acid in Arthri-Flex Advantage + Vitamin D3 against 900 products80 mg per serving; the middle half of products list 10 mg to 100 mg, the median 50 mg.80 mg

Higher than 62% of 900 products listing hyaluronic acid (median 50 mg). Per day at the most servings: 160 mg.

Flexicol Proprietary BlendFlexicol Proprietary Blend Note: containing1,045 mg
premium Chicken Sternum Type II Collagenas Chondroitin Sulfatepremium Chicken Sternum Type II Collagen (Form: naturally occurring Chondroitin Sulfate)in the blend, no amount given
Hyaluronic Acidas Sodium HyaluronateHyaluronic Acid (Form: as Sodium Hyaluronate)in the blend, no amount given
Boron Glycinatein the blend, no amount given

The label names the compound (Boron Glycinate); its amount is likely the compound's weight, not the boron it holds, so it is not placed among other products.

Boswellia serrata extractin the blend, no amount given
Grape seed extractin the blend, no amount given
White Willow bark extractin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 233355 (entered August 23, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 2 servings a day, the most its directions give, the label lists 400 mg of magnesium, 1.1 times the adult Tolerable Upper Intake Level.
  • Its 220 mcg of molybdenum is higher than 97% of the 4,390 molybdenum products that print an amount; 119 list more.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Arthri-Flex Advantage + Vitamin D3's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As a dietary supplement, adults take four (4) tablets daily, two (2) in the morning and two (2) in the afternoon, preferably with meals, or as directed by a healthcare provider.
Warnings
Do not exceed recommended dosage.
Warning: If you are diabetic, consult your physician before using this product.
If you have a Shellfish allergy please consult your physician before using this product.
Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.
Stop use and contact a physician if adverse reactions occur.
Keep out of reach of children.
Do not use if product appears to be tampered with or seal is broken.
Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.
Allergens and what it does not contain
No added sugar, yeast, starch, soy, corn, dairy, gluten, preservatives, or artificial flavors.
Gluten free Bovine free
Storage
Store at room temperature.

Source: label statements in DSLD label 233355.

What else is on the label?

Other ingredients: Cellulose, Stearic Acid, Croscarmellose Sodium, Silicon Dioxide, Polyvinyl Alcohol, Polyplasdone, Titanium Dioxide, Magnesium Stearate, PEG, Talc.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Guaranteed Quality Laboratory Tested.

How many labels does Arthri-Flex Advantage + Vitamin D3 have?

One label is on file, entered on August 23, 2020.

  1. Label 233355 (current) Entered August 23, 2020 · off the market August 5, 2020 · 180 coated tablets · UPC 7 40985 27066 0

DSLD also links this label to: Arthri-Flex Advantage + Vitamin D3 (package size difference, same product), Arthri-Flex Advantage + Vitamin D3 (image difference, same product), Arthri-Flex Advantage + Vitamin D3 (package size difference, same product), Arthri-Flex Advantage + Vitamin D3 (package size difference, same product), Arthri-Flex Advantage + Vitamin D3 (package size difference, same product), Arthri-Flex Advantage + Vitamin D3 (image difference, same product), Arthri-Flex Advantage + Vitamin D3 (package size difference, same product), Arthri-Flex Advantage + Vitamin D3 (package size difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names 21st Century HealthCare, Inc. (manufacturer), Tempe, AZ. All 21st Century HealthCare products.

Where next?