Active B12-Folate

by ProThera · tablet or pill · 60 tablets

  • Off the market since October 2021 (NIH)
  • UPC 8 28054 00132 9
  • DSLD label 44600
  • Serving 1 tablet
  • 60 servings

Active B12-Folate by ProThera lists 2 ingredients, 2 with an amount per serving of 1 tablet, such as 800 mcg of folate and 1,000 mcg of vitamin B12. Its current label entered the NIH Dietary Supplement Label Database on April 24, 2015.

What is in Active B12-Folate?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Active B12-Folate: Supplement Facts rows against the market (DSLD label 44600, January 2026 release)
IngredientAmount% DVAmong products listing it
Folateas Metafolin(R) L-5-MethyltetrahydrofolateFolate (Form: as Metafolin(R) L-5-Methyltetrahydrofolate)800 mcg200%Folate in Active B12-Folate against 7,022 products800 mcg per serving; the middle half of products list 200 mcg to 400 mcg, the median 400 mcg.800 mcg

Higher than 81% of 7,022 products listing folate (median 400 mcg).

Vitamin B12as MethylcobalaminVitamin B12 (Form: as Methylcobalamin)1,000 mcg16,667%Vitamin B12 in Active B12-Folate against 14,425 products1,000 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg1,000 mcg

Higher than 89% of 14,425 products listing vitamin B12 (median 36 mcg).

Source: NIH ODS Dietary Supplement Label Database, label 44600 (entered April 24, 2015), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: 1 tablet daily with food.
Warnings
Do not use if full-bottle shrinkwrap is broken or missing.
KEEP OUT OF REACH OF CHILDREN.
Allergens and what it does not contain
Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten, yeast, and soybeans. Contains no artificial colors, flavors, or preservatives.
Storage
Store in a cool, dry place (59(0)F-85(0)F) away from direct light.

Source: label statements in DSLD label 44600.

What else is on the label?

Other ingredients: Mannitol, Vegetable Stearine, Silicon Dioxide, Carboxymethylcellulose Sodium, Magnesium Stearate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): METAFOLIN(R).

How many labels does Active B12-Folate have?

One label is on file, entered on April 24, 2015.

  1. Label 44600 (current) Entered April 24, 2015 · off the market October 8, 2021 · 60 tablets · UPC 8 28054 00132 9

DSLD also links this label to: Active B12-Folate (image difference, same product), Active B12-Folate (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names ProThera, Inc. (manufacturer), Reno, NV. All ProThera products.

Where next?