PlainVitamins

5-Hydroxytryptophan

by Thorne · capsule · 90 capsules

  • On the market (NIH)
  • UPC 6 93749 50302 6
  • DSLD label 288626
  • Serving 1 to 2 capsules; amounts per 2 capsules
  • 45 servings

5-Hydroxytryptophan by Thorne lists 2 ingredients, 2 with an amount per serving of 2 capsules, such as 6.8 mg of vitamin B6 and 100 mg of 5-htp. Its current label entered the NIH Dietary Supplement Label Database on August 23, 2023.

What is in 5-Hydroxytryptophan?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

5-Hydroxytryptophan: Supplement Facts rows against the market (DSLD label 288626, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin B6as Pyridoxal 5-Phosphate6.8 mg400%Vitamin B6 in 5-Hydroxytryptophan against 15,277 products6.8 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg6.8 mg

Higher than 52% of 15,277 products listing vitamin B6 (median 6 mg). Per day at the most servings: 20.4 mg.

5-Htp100 mg5-HTP in 5-Hydroxytryptophan against 676 products100 mg per serving; the middle half of products list 50 mg to 100 mg, the median 100 mg.100 mg

18% of 676 products listing 5-HTP give more (median 100 mg). Per day at the most servings: 300 mg.

Source: NIH ODS Dietary Supplement Label Database, label 288626 (entered August 23, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested use: Take 1-2 capsules three times daily or as recommended by your healthcare practitioner.
Warnings
Tamper evident: Use only if bottle is sealed.
Warning: If pregnant or nursing, do not use this product.
Allergens and what it does not contain
Gluten free
Storage
Store tightly sealed in a cool, dry place.

Source: label statements in DSLD label 288626.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Hypromellose, Leucine, Silicon Dioxide.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Manufactured in the USA using US & imported ingredients.

How many labels does 5-Hydroxytryptophan have?

3 labels are on file under this name since October 25, 2018: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 288626 (current) Entered August 23, 2023 · on the market · 90 capsules · UPC 6 93749 50302 6
  2. Label 260325 Entered December 18, 2021 · off the market December 9, 2022 · 90 capsules · UPC 6 93749 50302 6
  3. Label 182161 Entered October 25, 2018 · off the market October 4, 2021 · 90 capsules · UPC 6 93749 50302 6

DSLD also links this label to: 5-Hydroxy-Tryptophan (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Thorne Research, Inc. (manufacturer). All Thorne products.

Where next?