PlainVitamins

3-in-1 Joint Formula

by Irwin Naturals · softgel capsule · 90 liquid softgels

  • On the market (NIH)
  • UPC 7 10363 26242 6
  • DSLD label 292060
  • Serving 6 liquid softgels
  • 15 servings

3-in-1 Joint Formula by Irwin Naturals lists 22 ingredients, 20 with an amount per serving of 6 liquid softgels, such as 10 mg of vitamin E, 23 mg of niacin, 382 mcg DFE of folate and 120 mcg of vitamin B12; 2 sit inside a blend without their own amounts, beside 7 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on June 22, 2023.

What is in 3-in-1 Joint Formula?

Each row as the label prints it, per serving of 6 liquid softgels. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

3-in-1 Joint Formula: Supplement Facts rows against the market (DSLD label 292060, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories60 Calories
Total Fat3.5 g4%Fat (unspecified) in 3-in-1 Joint Formula against 11,965 products3.5 g per serving; the middle half of products list 1 g to 2.5 g, the median 1.5 g.3.5 g

Higher than 82% of 11,965 products listing fat (unspecified) (median 1.5 g).

Saturated Fat1 g4%Saturated fat in 3-in-1 Joint Formula against 5,234 products1 g per serving; the middle half of products list 0.5 g to 1.5 g, the median 1 g.1 g

34% of 5,234 products listing saturated fat give more (median 1 g).

Cholesterol15 mg5%Cholesterol in 3-in-1 Joint Formula against 5,275 products15 mg per serving; the middle half of products list 5 mg to 45 mg, the median 15 mg.15 mg

47% of 5,275 products listing cholesterol give more (median 15 mg).

Total Carbohydrates3 g1%Carbohydrate in 3-in-1 Joint Formula against 21,979 products3 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.3 g

47% of 21,979 products listing carbohydrate give more (median 3 g).

Dietary Fiber1 g2%Fiber in 3-in-1 Joint Formula against 6,987 products1 g per serving; the middle half of products list 1 g to 4 g, the median 2 g.1 g

56% of 6,987 products listing fiber give more (median 2 g).

Protein3 gProtein in 3-in-1 Joint Formula against 8,985 products3 g per serving; the middle half of products list 2 g to 24 g, the median 16 g.3 g

67% of 8,985 products listing protein give more (median 16 g).

Vitamin Eas D-Alpha-Tocopherol10 mg67%
Niacinas Niacinamide23 mg144%Niacin in 3-in-1 Joint Formula against 12,413 products23 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg23 mg

Higher than 55% of 12,413 products listing niacin (median 20 mg).

Folate382 mcg DFE96%
Folic Acid225 mcg
Vitamin B12as Cyanocobalamin120 mcg5,000%Vitamin B12 in 3-in-1 Joint Formula against 14,425 products120 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg120 mcg

Higher than 70% of 14,425 products listing vitamin B12 (median 36 mcg).

Manganeseas Manganese Gluconate7 mg304%Manganese in 3-in-1 Joint Formula against 7,016 products7 mg per serving; the middle half of products list 1 mg to 3.92 mg, the median 2 mg.DV 2.3 mgUL 11 mg7 mg

Higher than 92% of 7,016 products listing manganese (median 2 mg).

Sodium95 mg4%Sodium in 3-in-1 Joint Formula against 14,514 products95 mg per serving; the middle half of products list 15 mg to 142 mg, the median 55 mg.95 mg

Higher than 62% of 14,514 products listing sodium (median 55 mg).

Potassium250 mg5%Potassium in 3-in-1 Joint Formula against 11,614 products250 mg per serving; the middle half of products list 50 mg to 190 mg, the median 99 mg.DV 4,700 mg250 mg

Higher than 85% of 11,614 products listing potassium (median 99 mg).

Fish Oils3,180 mgFish Oil in 3-in-1 Joint Formula against 1,990 products3.18 g per serving; the middle half of products list 1 g to 2 g, the median 1.2 g.3.18 g

Higher than 94% of 1,990 products listing fish oil (median 1.2 g).

Omega-3 Fatty Acids1,035 mgOmega-3 in 3-in-1 Joint Formula against 2,714 products1,035 mg per serving; the middle half of products list 230 mg to 1,000 mg, the median 500 mg.1,035 mg

Higher than 78% of 2,714 products listing omega-3 (median 500 mg).

Glucosamine Sulfateas Glucosamine Sulfate 2KCl1,500 mgGlucosamine Sulfate in 3-in-1 Joint Formula against 875 products1.5 g per serving; the middle half of products list 0.5 g to 1.5 g, the median 1 g.1.5 g

Higher than 64% of 875 products listing glucosamine sulfate (median 1 g).

Chondroitin Sulfate1,200 mgChondroitin Sulfate in 3-in-1 Joint Formula against 950 products1,200 mg per serving; the middle half of products list 200 mg to 1,200 mg, the median 400 mg.1,200 mg

Higher than 74% of 950 products listing chondroitin sulfate (median 400 mg).

Flaxseed Oil150 mgFlaxseed Oil in 3-in-1 Joint Formula against 512 products0.15 g per serving; the middle half of products list 0.4 g to 1.15 g, the median 1 g.0.15 g

90% of 512 products listing flaxseed oil give more (median 1 g).

Methylsulfonylmethane150 mgMethylsulfonylmethane in 3-in-1 Joint Formula against 1,454 products150 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.150 mg

73% of 1,454 products listing methylsulfonylmethane give more (median 500 mg).

Indian Frankincense gum resin extractIndian Frankincense extract gum resin115 mgBoswellia in 3-in-1 Joint Formula against 665 products115 mg per serving; the middle half of products list 100 mg to 290 mg, the median 135 mg.115 mg

52% of 665 products listing boswellia give more (median 135 mg).

Boswellic Acids65% Boswellic acids74.75 mgBoswellic Acid in 3-in-1 Joint Formula against 54 products74.75 mg per serving; the middle half of products list 74.81 mg to 191.25 mg, the median 97.5 mg.74.75 mg

74% of 54 products listing boswellic acid give more (median 97.5 mg).

Stinging Nettle leaf extract70 mgStinging Nettle in 3-in-1 Joint Formula against 710 products70 mg per serving; the middle half of products list 50 mg to 300 mg, the median 120 mg.70 mg

67% of 710 products listing stinging nettle give more (median 120 mg).

Phytosterols0.8% Phytosterols0.56 mgPhytosterols in 3-in-1 Joint Formula against 440 products0.56 mg per serving; the middle half of products list 100 mg to 667 mg, the median 400 mg.0.56 mg

99% of 440 products listing phytosterols give more (median 400 mg).

Turmeric root extract40 mgTurmeric in 3-in-1 Joint Formula against 2,369 products40 mg per serving; the middle half of products list 50 mg to 500 mg, the median 150 mg.40 mg

82% of 2,369 products listing turmeric give more (median 150 mg).

Curcuminoids95% Curcuminoids38 mgCurcuminoid in 3-in-1 Joint Formula against 309 products38 mg per serving; the middle half of products list 40 mg to 300 mg, the median 100 mg.38 mg

78% of 309 products listing curcuminoid give more (median 100 mg).

Alpha-Lipoic Acid5 mgAlpha Lipoic Acid in 3-in-1 Joint Formula against 2,407 products5 mg per serving; the middle half of products list 25 mg to 150 mg, the median 50 mg.5 mg

92% of 2,407 products listing alpha lipoic acid give more (median 50 mg).

BioPerine Complex6 mg
Bioperineas Black Pepper Fruit Extract95% Piperinein the blend, no amount given
Ginger Rhizome Extractas Gingerols5% Gingerolsin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 292060 (entered June 22, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 7 mg of manganese is higher than 92% of the 7,016 manganese products that print an amount; 554 list more.
  • Its 3.18 g of fish oil is higher than 94% of the 1,990 fish oil products that print an amount; 128 list more.
  • 90% of the 512 products that print an amount of flaxseed oil list more than its 0.15 g of flaxseed oil (median 1 g).
  • 99% of the 440 products that print an amount of phytosterols list more than its 0.56 mg of phytosterols (median 400 mg).
  • 92% of the 2,407 products that print an amount of alpha lipoic acid list more than its 5 mg of alpha-lipoic acid (filed by NIH under alpha lipoic acid) (median 50 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: (Adult) Take six (6) liquid soft-gels per day with a meal and a full glass (8 oz) of water. May be taken all at once or in divided doses.
Warnings
Usage warnings: Do not use if safety seal is broken.
Check with your doctor before using the product if you are using medication or have any medical conditions. Do not use if you may become pregnant, are pregnant or nursing.
Do not use if you have a bile duct obstruction. Do not exceed recommended daily intake.
Not intended for use by persons under 18. Keep out of reach or children.
Warning: (State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.
Contains: Crustacean Shellfish (crab, lobster, shrimp), Fish (anchovy, sardine), Soy
Allergens and what it does not contain
No preservatives added.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 292060.

What else is on the label?

Other ingredients: Gelatin, Water, Purified, Glycerin, Soy Lecithin, Annatto, Maltodextrin, Titanium Dioxide, Dicalcium Phosphate, Beeswax, St. John's Bread, Soybean Oil, Turmeric.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Pass Quality Tested Guaranteed.

How many labels does 3-in-1 Joint Formula have?

6 labels are on file under this name since November 25, 2011: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 292060 (current) Entered June 22, 2023 · on the market · 90 liquid softgels · UPC 7 10363 26242 6
  2. Label 256292 Entered October 22, 2021 · off the market April 22, 2022 · 90 liquid softgels · UPC 7 10363 26242 6
  3. Label 206842 Entered October 23, 2019 · off the market July 7, 2021 · 90 liquid softgels · UPC 7 10363 26242 6
  4. Label 57345 Entered March 24, 2016 · off the market March 7, 2019 · 90 liquid softgels · UPC 7 10363 26242 6
  5. Label 44658 Entered April 24, 2015 · off the market August 4, 2015 · 90 liquid softgels · UPC 7 10363 26242 6
  6. Label 2454 Entered November 25, 2011 · off the market March 23, 2015 · 90 liquid soft-gels · UPC 7 10363 26242 6

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Irwin Naturals (manufacturer, distributor), Los Angeles, CA. All Irwin Naturals products.

Where next?