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Most Common Supplement Ingredients

The top 50 ingredients found most frequently across dietary supplements in the NIH DSLD database.

Top 12 ingredients by product label count

Number of NIH DSLD product labels declaring each ingredient (top 12 of 50).

products
Source NIH Dietary Supplement Label Database (DSLD) As of 2026

Top 6 ingredients (compact)

Top 6 most prevalent ingredients, quick visual reference.

products
Source NIH Dietary Supplement Label Database (DSLD) As of 2026

Top 12 ingredients, full ranking

All twelve most-prevalent ingredients for category-comparison reading.

products
Source NIH Dietary Supplement Label Database (DSLD) As of 2026
Rank Ingredient Name Category Product Count
1 Cellulose Fiber 38,530
2 Silicon Mineral 35,609
3 Magnesium Non-nutrient/non-botanical 27,703
4 Calcium Mineral 25,916
5 Gelatin Protein 24,357
6 Water Other 23,872
7 Glycerol Other 19,909
8 Vitamin C Vitamin 19,523
9 Carbohydrate Sugar 18,301
10 Fat (unspecified) Fat 16,764
11 Flavor Other 16,729
12 Stearic Acid Fatty acid 16,405
13 Magnesium stearate Other 16,235
14 Sodium Mineral 14,494
15 capsule Other 14,245
16 Vitamin E Vitamin 13,833
17 Vitamin D Vitamin 13,348
18 Sugar Sugar 12,924
19 Hypromellose Other 12,480
20 Zinc Mineral 12,064
21 Potassium Mineral 11,807
22 Vitamin B12 Vitamin 11,621
23 Vitamin B6 Vitamin 10,891
24 Citric Acid Non-nutrient/non-botanical 10,082
25 Rice Botanical 9,610
26 Vitamin A Vitamin 9,398
27 Niacin Vitamin 9,293
28 Folate Vitamin 9,262
29 lecithin Fat 9,150
30 Saturated fat Fat 9,053
31 Cholesterol Fat 8,999
32 Iron Mineral 8,704
33 Riboflavin Vitamin 8,001
34 Biotin Vitamin 7,845
35 Thiamin Vitamin 7,759
36 Fiber (unspecified) Fiber 7,667
37 Blend Blend 7,224
38 Maltodextrin Complex carbohydrate 7,115
39 Protein (unspecified) Protein 6,961
40 Chromium Mineral 6,864
41 Selenium Mineral 6,831
42 Proprietary Blend Blend 6,717
43 Manganese Mineral 6,426
44 Color Other 6,418
45 Copper Mineral 6,016
46 DHA (Docosahexaenoic Acid) Fatty acid 6,004
47 Iodine Mineral 5,917
48 Sucralose Non-nutrient/non-botanical 5,697
49 Header Other 5,504
50 EPA (Eicosapentaenoic Acid) Fatty acid 5,414

Source: NIH Dietary Supplement Label Database (DSLD) NIH Dietary Supplement Label Database (DSLD) Counts reflect total products listing each ingredient

How to read this ranking

Each row counts how many distinct dietary supplement product labels in the NIH Dietary Supplement Label Database (DSLD) declare the listed ingredient at any amount. The ranking is a measure of prevalence in the US supplement market, not a measure of efficacy, safety, bioavailability, or quality. Ingredients that show up in more products are simply more common in formulations , they may be there because they are well-studied, because they are inexpensive, because they are required by FDA labeling rules in certain product types, or because they appear in many multi-ingredient blends as fillers or supporting compounds.

Counts include both currently on-market and historical (off-market) labels, the DSLD preserves discontinued labels for research and historical lookup. Click any ingredient name to see its NIH ODS dosing context (RDA, UL, IU↔mcg conversion, drug interactions, pregnancy notes) plus the full list of products containing that ingredient.

Why prevalence varies across categories

Vitamins and minerals tend to dominate the ranking because nearly every multivitamin contains at least the eight or nine major ones (vitamins A, C, D, E, K, B-complex, calcium, magnesium, zinc, iron). Botanicals appear less often per category but show much wider category diversity, there are thousands of distinct botanical ingredients used across the market, each appearing in a smaller number of specialized formulas. Excipients (cellulose, magnesium stearate, gelatin, microcrystalline cellulose, silicon dioxide) also rank highly because they are required functional components of capsules, tablets, and powder formulations, their presence is a manufacturing fact, not a nutritional one.

For meaningful comparisons, treat the prevalence count as one signal among many. A vitamin appearing in 70% of multivitamins tells you it is a market default, not that it is right for any individual person. Always check the dosing context on the per-ingredient page (linked above) and consult a healthcare provider before starting any supplement. The methodology page documents how ingredient names are normalized and aggregated.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. This page draws directly on the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.