SAM-e 1000 mg
by Mental Refreshment · capsule · 90 capsules
- On the market (NIH)
- UPC 7 138073 751338
- DSLD label 247682
- Serving 4 capsules
- 22 servings
SAM-e 1000 mg by Mental Refreshment lists one ingredient: 1,000 mg of SAM-e per serving of 4 capsules. Its current label entered the NIH Dietary Supplement Label Database on May 22, 2021.
What is in SAM-e 1000 mg?
Each row as the label prints it, per serving of 4 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| SAM-eas S-Adenosyl-L-Methionine Disulfate TosylateSAM-e (Form: as S-Adenosyl-L-Methionine Disulfate Tosylate) | 1,000 mg | Higher than 97% of 163 products listing SAMe (median 200 mg). |
Source: NIH ODS Dietary Supplement Label Database, label 247682 (entered May 22, 2021), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:
- Its 1,000 mg of SAM-e (filed by NIH under SAMe) is higher than 97% of the 163 SAMe products that print an amount; 3 list more.
The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
6 products list the very same ingredients; the nearest amounts come first.
- SAMe (S,S Isomer) 1100 mgNusaPure same ingredients
- SAM-e 400 mgSuperSmart same ingredients
- SAM-e 1500 mgMental Refreshment same ingredients
- SAM-e 1500 mgNasaBe'Ahava same ingredients
- SAM-e 500 mgNasaBe'Ahava same ingredients
- SAM-e 400 mgGNC · off the market same ingredients
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Directions: For adults, take four (4) capsules daily preferably with a meal.
- Warnings
- Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.
- Discontinue use and consult your doctor if any adverse reactions occur.
- Not intended for use by persons under the age of 18. Keep out of reach of children.
- Allergens and what it does not contain
- Contains No: Artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.
- Storage
- Store in a dry place and avoid excessive heat.
Source: label statements in DSLD label 247682.
What else is on the label?
Other ingredients: Gelatin, Rice powder.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Made in the USA GMP Good Manufacturing Practice Consistent Quality Manufactured in a FDA Registered facility that conforms to GMP standards.
How many labels does SAM-e 1000 mg have?
One label is on file, entered on May 22, 2021.
- Label 247682 (current) Entered May 22, 2021 · on the market · 90 capsules · UPC 7 138073 751338
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Mental Refreshment Nutrition (distributor), Severna Park, MD. All Mental Refreshment products.