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Irwin Naturals · Botanical with Nutrients supplement

Pure Defense Mushroom-8 Immune Support

33 ingredients on file in the NIH Dietary Supplement Label Database, top 5% by ingredient count. Currently on-market in the U.S.

33
Ingredients
Top 5%
By ingredient count
10
Nutrient categories

Pure Defense Mushroom-8 Immune Support is a botanical with nutrients supplement by Irwin Naturals in softgel capsule form, listing 33 ingredients in the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. Currently listed as on-market. Daily Value percentages shown below are based on FDA reference daily intake amounts for adults.

Product Details

Form
Softgel Capsule
Database Entry Date
2023-05-24
Ingredients
33

Supplement Facts (33 Ingredients)

Calories
Amount
Not disclosed on label
% DV
Not reported
Total Fat
Amount
Not disclosed on label
% DV
Not reported
Total Carbohydrates
Amount
Not disclosed on label
% DV
Not reported
Protein
Amount
Not disclosed on label
% DV
Not reported
Vitamin C
Amount
Not disclosed on label
% DV
Not reported
Zinc
Amount
Not disclosed on label
% DV
Not reported
Selenium
Amount
Not disclosed on label
% DV
Not reported
Extra Virgin Olive Oil
Amount
Not disclosed on label
% DV
Not reported
Flaxseed Oil
Amount
Not disclosed on label
% DV
Not reported
Astragalus Root Extract
Amount
Not disclosed on label
% DV
Not reported
Echinacea purpurea root extract
Amount
Not disclosed on label
% DV
Not reported
Black Elder Fruit Extract
Amount
Not disclosed on label
% DV
Not reported
Licorice, Powder
Amount
Not disclosed on label
% DV
Not reported
organic Reishi Mushroom powder
Amount
Not disclosed on label
% DV
Not reported
organic Turkey Tail Mushroom powder
Amount
Not disclosed on label
% DV
Not reported
Organic Agaricus Mushroom powder
Amount
Not disclosed on label
% DV
Not reported
organic Chaga Mushroom powder
Amount
Not disclosed on label
% DV
Not reported
organic Cordyceps Mushroom powder
Amount
Not disclosed on label
% DV
Not reported
organic Lion's Mane Mushroom powder
Amount
Not disclosed on label
% DV
Not reported
organic Maitake Mushroom powder
Amount
Not disclosed on label
% DV
Not reported
organic Shiitake Mushroom powder
Amount
Not disclosed on label
% DV
Not reported
BioPerine Complex
Amount
Not disclosed on label
% DV
Not reported
BioPerine
Amount
Not disclosed on label
% DV
Not reported
Ginger Rhizome Extract
Amount
Not disclosed on label
% DV
Not reported
Gelatin
Amount
Not disclosed on label
% DV
Not reported
Water, Purified
Amount
Not disclosed on label
% DV
Not reported
Glycerin
Amount
Not disclosed on label
% DV
Not reported
Beeswax
Amount
Not disclosed on label
% DV
Not reported
Soy Lecithin
Amount
Not disclosed on label
% DV
Not reported
St. John's Bread
Amount
Not disclosed on label
% DV
Not reported
Maltodextrin
Amount
Not disclosed on label
% DV
Not reported
Titanium Dioxide
Amount
Not disclosed on label
% DV
Not reported
Silicon Dioxide
Amount
Not disclosed on label
% DV
Not reported

How does Pure Defense Mushroom-8 Immune Support compare?

Ingredients listed on each label, against the botanical with nutrients category average of 16. Data from the NIH DSLD.

Pure Defense Mushroom-8 Immune Support33
1 Liver & Organ Quick Detox24
Botanical with Nutrients average16

Pure Defense Mushroom-8 Immune Support lists 9 ingredients more than 1 Liver & Organ Quick Detox. That is 17 above the botanical with nutrients average.

What the Label Data Shows

According to NIH DSLD label rows, Pure Defense Mushroom-8 Immune Support sits in the top 5% of products with a countable formula by declared ingredient count.

With 33 ingredients on the label, Pure Defense Mushroom-8 Immune Support is one of the more extensive botanical with nutrients supplement formulas from Irwin Naturals in the NIH Dietary Supplement Label Database (DSLD), sold in softgel capsule form. These ingredients span 10 nutrient categories, other, botanical, fat, mineral, and 6 more, reflecting a multi-component formula rather than a single-nutrient product.

Across a broader 33-ingredient formula, 33 of 33 have no percentage Daily Value reported in this DSLD source record, so the available data cannot establish their FDA reference status.

Market status matters for supplement research. This product is currently listed as on-market in the DSLD, with its label first entered into the database on 2023-05-24. On-market products are currently being distributed in the United States, though the DSLD does not verify the accuracy of label claims or evaluate safety or efficacy.

About the DSLD database

The DSLD is a label database, not an FDA approval list, under the 1994 DSHEA framework, dietary supplements do not require pre-market approval, and label information reflects what manufacturers self-declare rather than independent laboratory verification. This page presents factual label data for reference only and is not medical advice; consult a licensed healthcare provider before making decisions about any supplement.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) Supplement label data for Pure Defense Mushroom-8 Immune Support: ingredients, % Daily Value, market status, brand · 2026 DSLD captures manufacturer-self-declared label information; the NIH does not verify accuracy or evaluate safety/efficacy. Dietary supplements are regulated under DSHEA 1994, no pre-market FDA approval is required.

Nationwide supplements with similar label profiles

Two DSLD-derived peer sets for Pure Defense Mushroom-8 Immune Support, both outside the Irwin Naturals brand so the neighborhoods are not catalog containment (the same-type Nearby block above stays type-local).

Ingredient Breakdown by Category

other
11
Calories, organic Reishi Mushroom powder, organic Turkey Tail Mushroom powder, +8 more
botanical
7
Astragalus Root Extract, Echinacea purpurea root extract, Black Elder Fruit Extract, +4 more
fat
4
Total Fat, Extra Virgin Olive Oil, Flaxseed Oil, +1 more
mineral
4
Zinc, Selenium, Titanium Dioxide, +1 more
protein
2
Protein, Gelatin
sugar
1
Total Carbohydrates
vitamin
1
Vitamin C
blend
1
BioPerine Complex
animal part or source
1
Beeswax
complex carbohydrate
1
Maltodextrin

Daily Value Coverage

0
Above 100% DV
0
Below 100% DV
33
%DV not reported in source

Frequently Asked Questions

What ingredients are in Pure Defense Mushroom-8 Immune Support?
Pure Defense Mushroom-8 Immune Support contains 33 ingredients. By declared ingredient count it sits in the top 5% of DSLD products PlainVitamins places. Ingredients span 10 categories: other, botanical, fat, mineral, protein, sugar, vitamin, blend, animal part or source, complex carbohydrate.
Who manufactures Pure Defense Mushroom-8 Immune Support?
Pure Defense Mushroom-8 Immune Support is currently manufactured by Irwin Naturals. It is classified as a Botanical with Nutrients supplement in softgel capsule form.
Is Pure Defense Mushroom-8 Immune Support still available for purchase?
Yes, Pure Defense Mushroom-8 Immune Support is currently listed as on-market in the NIH DSLD database.
What is the serving size of Pure Defense Mushroom-8 Immune Support?
The serving size is not specified.
What type of supplement is Pure Defense Mushroom-8 Immune Support?
Pure Defense Mushroom-8 Immune Support is classified as a "Botanical with Nutrients" supplement in the NIH database. This category includes products primarily composed of botanical with nutrients ingredients. Across the full DSLD catalog, products fall into 9 possible categories: Vitamin, Mineral, Botanical, Amino Acid & Protein, Non-Nutrient, Fat & Fatty Acid, Multi-Vitamin & Mineral, Botanical with Nutrients, and Other Combinations.
Data Sources & Methodology

Data as of 2025. Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD).

Supplement label data sourced from the Source: NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD contains label information from dietary supplement products marketed in the United States.

Daily Value (DV) percentages are based on Source: FDA 21 CFR 101.9 Reference Daily Intake (RDI) values for adults. Products marked "Off Market" may no longer be available for purchase but their label data remains in the database for reference.

Disclaimer, Not Medical Advice

Label data from the Source: NIH Dietary Supplement Label Database (DSLD). This information is for educational and reference purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or combining any dietary supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. This page draws directly on the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.