PlainVitamins

Pure Defense Mushroom-8 Immune Support

by Irwin Naturals · softgel capsule · 60 liquid soft-gels

  • On the market (NIH)
  • UPC 7 10363 59715 3
  • DSLD label 292087
  • Serving 3 liquid softgels
  • 20 servings

Pure Defense Mushroom-8 Immune Support by Irwin Naturals lists 19 ingredients, 17 with an amount per serving of 3 liquid softgels, such as 200 mg of vitamin C, 15 mg of zinc, 55 mcg of selenium and 1,050 mg of extra virgin olive oil; 2 sit inside a blend without their own amounts, beside 3 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on May 24, 2023.

What is in Pure Defense Mushroom-8 Immune Support?

Each row as the label prints it, per serving of 3 liquid softgels. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Pure Defense Mushroom-8 Immune Support: Supplement Facts rows against the market (DSLD label 292087, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories30 Calories
Total Fat2 g3%Fat (unspecified) in Pure Defense Mushroom-8 Immune Support against 11,965 products2 g per serving; the middle half of products list 1 g to 2.5 g, the median 1.5 g.2 g

Higher than 56% of 11,965 products listing fat (unspecified) (median 1.5 g).

Total Carbohydrates2 g1%Carbohydrate in Pure Defense Mushroom-8 Immune Support against 21,979 products2 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.2 g

58% of 21,979 products listing carbohydrate give more (median 3 g).

Protein1 gProtein in Pure Defense Mushroom-8 Immune Support against 8,985 products1 g per serving; the middle half of products list 2 g to 24 g, the median 16 g.1 g

77% of 8,985 products listing protein give more (median 16 g).

Vitamin Cas Ascorbic Acid200 mg222%Vitamin C in Pure Defense Mushroom-8 Immune Support against 18,583 products200 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg200 mg

Higher than 63% of 18,583 products listing vitamin C (median 100 mg).

Zincas Zinc Citrate15 mg136%Zinc in Pure Defense Mushroom-8 Immune Support against 13,186 products15 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg15 mg

Higher than 56% of 13,186 products listing zinc (median 11 mg).

Seleniumas L-Selenomethionine55 mcg100%Selenium in Pure Defense Mushroom-8 Immune Support against 7,658 products55 mcg per serving; the middle half of products list 27 mcg to 100 mcg, the median 55 mcg.DV 55 mcgUL 400 mcg55 mcg

50% of 7,658 products listing selenium give more (median 55 mcg).

Extra Virgin Olive Oil1,050 mgOlive Oil in Pure Defense Mushroom-8 Immune Support against 70 products1,050 mg per serving; the middle half of products list 200 mg to 1,200 mg, the median 500 mg.1,050 mg

Higher than 67% of 70 products listing olive oil (median 500 mg).

Flaxseed Oil1,050 mgFlaxseed Oil in Pure Defense Mushroom-8 Immune Support against 512 products1.05 g per serving; the middle half of products list 0.4 g to 1.15 g, the median 1 g.1.05 g

Higher than 73% of 512 products listing flaxseed oil (median 1 g).

Astragalus Root Extractas Astragalus membranaceus Root Extract20:1200 mgAstragalus in Pure Defense Mushroom-8 Immune Support against 604 products200 mg per serving; the middle half of products list 50 mg to 405 mg, the median 132.5 mg.200 mg

Higher than 55% of 604 products listing astragalus (median 132.5 mg).

Echinacea purpurea root extract10:1200 mgEchinacea purpurea in Pure Defense Mushroom-8 Immune Support against 484 products200 mg per serving; the middle half of products list 50 mg to 400 mg, the median 200 mg.200 mg

48% of 484 products listing echinacea purpurea give more (median 200 mg).

Black Elder Fruit Extract10:1200 mgEuropean Elder in Pure Defense Mushroom-8 Immune Support against 920 products200 mg per serving; the middle half of products list 50 mg to 400 mg, the median 150 mg.200 mg

Higher than 54% of 920 products listing european elder (median 150 mg).

Licorice, Powder100 mgLicorice in Pure Defense Mushroom-8 Immune Support against 888 products100 mg per serving; the middle half of products list 42 mg to 300 mg, the median 100 mg.100 mg

42% of 888 products listing licorice give more (median 100 mg).

organic Reishi Mushroom powder100 mgReishi mushroom in Pure Defense Mushroom-8 Immune Support against 500 products100 mg per serving; the middle half of products list 50 mg to 500 mg, the median 180 mg.100 mg

58% of 500 products listing reishi mushroom give more (median 180 mg).

organic Turkey Tail Mushroom powder100 mgCoriolus mushroom in Pure Defense Mushroom-8 Immune Support against 147 products100 mg per serving; the middle half of products list 100 mg to 1,000 mg, the median 300 mg.100 mg

74% of 147 products listing coriolus mushroom give more (median 300 mg).

Organic Agaricus Mushroom powder50 mgAgaricus mushroom in Pure Defense Mushroom-8 Immune Support against 72 products50 mg per serving; the middle half of products list 70 mg to 500 mg, the median 250 mg.50 mg

76% of 72 products listing agaricus mushroom give more (median 250 mg).

organic Chaga Mushroom powder50 mgChaga in Pure Defense Mushroom-8 Immune Support against 163 products50 mg per serving; the middle half of products list 100 mg to 500 mg, the median 200 mg.50 mg

84% of 163 products listing chaga give more (median 200 mg).

organic Cordyceps Mushroom powder50 mgCordyceps in Pure Defense Mushroom-8 Immune Support against 450 products50 mg per serving; the middle half of products list 100 mg to 600 mg, the median 250 mg.50 mg

82% of 450 products listing cordyceps give more (median 250 mg).

organic Lion's Mane Mushroom powder50 mgHericium mushroom in Pure Defense Mushroom-8 Immune Support against 373 products50 mg per serving; the middle half of products list 200 mg to 1,000 mg, the median 500 mg.50 mg

91% of 373 products listing hericium mushroom give more (median 500 mg).

organic Maitake Mushroom powder50 mgMaitake Mushroom in Pure Defense Mushroom-8 Immune Support against 327 products50 mg per serving; the middle half of products list 30 mg to 200 mg, the median 100 mg.50 mg

58% of 327 products listing maitake mushroom give more (median 100 mg).

organic Shiitake Mushroom powder50 mgShiitake Mushroom in Pure Defense Mushroom-8 Immune Support against 256 products50 mg per serving; the middle half of products list 33.75 mg to 200 mg, the median 100 mg.50 mg

61% of 256 products listing shiitake mushroom give more (median 100 mg).

BioPerine Complex6 mg
BioPerineas Black Pepper Fruit Extract95% piperinein the blend, no amount given
Ginger Rhizome Extractas Gingerols5% gingerolsin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 292087 (entered May 24, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 76% of the 72 products that print an amount of agaricus mushroom list more than its 50 mg of organic agaricus mushroom powder (filed by NIH under agaricus mushroom) (median 250 mg).
  • 84% of the 163 products that print an amount of chaga list more than its 50 mg of organic chaga mushroom powder (filed by NIH under chaga) (median 200 mg).
  • 82% of the 450 products that print an amount of cordyceps list more than its 50 mg of organic cordyceps mushroom powder (filed by NIH under cordyceps) (median 250 mg).
  • 91% of the 373 products that print an amount of hericium mushroom list more than its 50 mg of organic Lion's mane mushroom powder (filed by NIH under hericium mushroom) (median 500 mg).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Pure Defense Mushroom-8 Immune Support's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
This product can be used daily or on an as-needed basis to support your immune system.
Directions: (Adult) for general immune support, take three (3) liquid soft-gels daily with a meal and a full glass of (8oz) of water.
Warnings
Usage warnings: do not use if safety seal is broken.
Check with your doctor before using this product if you are using medication or have any medical conditions. Do not use if you may become pregnant, are pregnant or nursing.
Do not exceed recommended daily intake.
Not intended for use by persons under 18. Keep out of reach of children.
Contains: soy
Allergens and what it does not contain
No preservatives added.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 292087.

What else is on the label?

Other ingredients: Gelatin, Water, Purified, Glycerin, Beeswax, Soy Lecithin, St. John's Bread, Maltodextrin, Titanium Dioxide, Silicon Dioxide.

How many labels does Pure Defense Mushroom-8 Immune Support have?

2 labels are on file under this name since October 22, 2021: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 292087 (current) Entered May 24, 2023 · on the market · 60 liquid soft-gels · UPC 7 10363 59715 3
  2. Label 256608 Entered October 22, 2021 · off the market April 22, 2022 · 60 liquid softgels · UPC 7 10363 59715 3

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Irwin Naturals (manufacturer, distributor), Los Angeles, CA. All Irwin Naturals products.

Where next?