Proto-Zyme
by Priority One Nutritional Supplements · tablet or pill · 180 tablets
- On the market (NIH)
- UPC 8 15354 02116 4
- DSLD label 277407
- Serving 2 tablets
- 90 servings
Proto-Zyme by Priority One Nutritional Supplements lists 12 ingredients, 9 with an amount per serving of 2 tablets, such as 4 mg of zinc, 100 mg of papain, 75 mg of bromelain and 60 mg of rutin; 3 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on October 24, 2022.
What is in Proto-Zyme?
Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Zincas Zinc Gluconate | 4 mg | 36% | 81% of 13,186 products listing zinc give more (median 11 mg). Per day at the most servings: 12 mg. |
| Papain300,000 USP/Serving | 100 mg | Higher than 77% of 607 products listing papain (median 40 mg). Per day at the most servings: 300 mg. | |
| Bromelain270MCU/Serving | 75 mg | Higher than 53% of 1,337 products listing bromelain (median 50 mg). Per day at the most servings: 225 mg. | |
| Rutinas Japanese Sophora Flower Extract | 60 mg | Higher than 81% of 1,232 products listing rutin (median 25 mg). Per day at the most servings: 180 mg. | |
| Trypsin1:75 Extract (2.625 USP/Serving) | 35 mg | 71% of 77 products listing trypsin give more (median 75 mg). Per day at the most servings: 105 mg. | |
| Pancreatin 8x | 200 mg | ||
| Amylase40,000 USP/serving | in the blend, no amount given | ||
| Lipase6,600 USP/serving | in the blend, no amount given | ||
| Protease40,000 USP/serving | in the blend, no amount given | ||
| Lysozyme | 10 mg | ||
| Cellulase40CU/serving | 2 mg | 83% of 184 products listing cellulase give more (median 10 mg). Per day at the most servings: 6 mg. | |
| Alpha-Chymotrypsin75 USP/serving | 1 mg | 80% of 49 products listing chymotrypsin give more (median 3 mg). Per day at the most servings: 3 mg. | |
| Thymus | 35 mg | 70% of 122 products listing thymus give more (median 50.5 mg). Per day at the most servings: 105 mg. |
Source: NIH ODS Dietary Supplement Label Database, label 277407 (entered October 24, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:
- 83% of the 184 products that print an amount of cellulase list more than its 2 mg of cellulase (median 10 mg).
The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
The products whose ingredient lists overlap most with Proto-Zyme's, rare ingredients counting for more.
- Priority ZymePriority One Nutritional Supplements 11 shared, 89% alike
- ArteriozymeEnergique 11 shared, 77% alike
- Mega-Zyme Systemic EnzymesEnzymatic Therapy · off the market 8 shared, 71% alike
- Mega-ZymeEnzymatic Therapy · off the market 8 shared, 71% alike
- Wholezyme UltraWhole Foods Market 8 shared, 71% alike
- Lyso-Lyph-ForteNutri-West 9 shared, 64% alike
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Recommendations: Take two (2) tablets three times daily, or as directed by your physician.
- Warnings
- Warning: If you are pregnant or breast feeding, consult your physician before using this product.
- Keep out of reach of children.
- For professional use only.
- Allergens and what it does not contain
- Contains no preservatives. Non-GMO
- Storage
- Keep container tightly closed, store in a cool, dry place.
Source: label statements in DSLD label 277407.
What else is on the label?
Other ingredients: Dicalcium Phosphate, Vegetable Stearic Acid, Croscarmellose Sodium, Microcrystalline Cellulose, Silicon Dioxide, Methylcellulose, Water, Purified, Lysozyme.
Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GMP Certified.
How many labels does Proto-Zyme have?
3 labels are on file under this name since September 25, 2020: other sizes, label designs and reformulations. The current one leads this page.
- Label 277407 (current) Entered October 24, 2022 · on the market · 180 tablets · UPC 8 15354 02116 4
- Label 255617 Entered September 24, 2021 · off the market March 16, 2022 · 180 tablets · UPC 8 15354 02116 4
- Label 236865 Entered September 25, 2020 · off the market June 15, 2021 · 180 tablets · UPC 8 15354 02116 4
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Priority One Nutritional Supplements, Inc. (distributor). All Priority One Nutritional Supplements products.