St. John's Wort 450 mg

by Nature Made · tablet or pill · 40 tablets

  • On the market (NIH)
  • UPC 3 31604 14159 3
  • DSLD label 180412
  • Serving 2 tablets
  • 20 servings

St. John's Wort 450 mg by Nature Made lists 2 ingredients, 2 with an amount per serving of 2 tablets, such as 900 mg of St. John's wort aerial parts extract. Its current label entered the NIH Dietary Supplement Label Database on September 21, 2018.

What is in St. John's Wort 450 mg?

Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

St. John's Wort 450 mg: Supplement Facts rows against the market (DSLD label 180412, January 2026 release)
IngredientAmount% DVAmong products listing it
St. John's Wort aerial parts extract900 mgSt. John's Wort in St. John's Wort 450 mg against 338 products900 mg per serving; the middle half of products list 250 mg to 450 mg, the median 300 mg.900 mg

Higher than 87% of 338 products listing St. John's wort (median 300 mg).

HypericinHypericin Note: by UV2.7 mgHypericin in St. John's Wort 450 mg against 33 products2,700 mcg per serving; the middle half of products list 900 mcg to 1,800 mcg, the median 900 mcg.2,700 mcg

Higher than 79% of 33 products listing hypericin (median 900 mcg).

Source: NIH ODS Dietary Supplement Label Database, label 180412 (entered September 21, 2018), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
1 dose per day
Suggested use: For adults, take two tablets one time daily with water at mealtimes. For easier swallowing, take with water before and during ingestion.
Warnings
Keep out of reach of children. Caution: Not for use by children.
If you are pregnant or nursing, consult a health professional before taking this product. There is a possibility St. John's Wort may interact or interfere with some prescription drugs, including blood thinners, oral contraceptives and antidepressants. Consult with your physician or pharmacist before using this product if you are taking any prescription drug, and visit NatureMade.com for additional contraindication information.
Side effects, such as rash, dizziness or nausea, may occur. St. John's Wort is a stimulant and may worsen feelings of anxiety in some people. Psychosis is a rare but possible side effect of take St. John's Wort, particularly in people who have or are at risk for mental health disorders, including bipolar disorder. Limit exposure to the sun as St. John's Wort may cause increased photosensitivity in fair skinned individuals. Discontinue use and consult a health care provider if you experience any side effects. Do not use if imprinted seal under cap is broken or missing.
Allergens and what it does not contain
No color added No artificial flavors No preservatives No yeast Gluten free
Storage
Keep bottle tightly closed. Store in a cool, dry place.

Source: label statements in DSLD label 180412.

What else is on the label?

Other ingredients: Cellulose Gel, Croscarmellose Sodium, Maltodextrin, Sodium Starch Glycolate, Silicon Dioxide, Hypromellose, Magnesium Stearate, Polyethylene Glycol, Stearic Acid.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Guaranteed Purity Quality.

How many labels does St. John's Wort 450 mg have?

One label is on file, entered on September 21, 2018.

  1. Label 180412 (current) Entered September 21, 2018 · on the market · 40 tablets · UPC 3 31604 14159 3

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature Made Nutritional Products (distributor), Mission Hills, CA, U.S.A.. All Nature Made products.

Where next?