PlainVitamins

St. John's Wort 450

by Source Naturals · tablet or pill · 180 tablets

  • On the market (NIH)
  • UPC 0 21078 01177 4
  • DSLD label 273078
  • Serving 1 tablet
  • 180 servings

St. John's Wort 450 by Source Naturals lists 2 ingredients, 2 with an amount per serving of 1 tablet, such as 450 mg of St. John's wort. Its current label entered the NIH Dietary Supplement Label Database on August 23, 2022.

What is in St. John's Wort 450?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

St. John's Wort 450: Supplement Facts rows against the market (DSLD label 273078, January 2026 release)
IngredientAmount% DVAmong products listing it
St. John's WortSt. John's Wort PlantPart: aerial parts Note: (standardized extract) (0.3%) (yielding)450 mgSt. John's Wort in St. John's Wort 450 against 338 products450 mg per serving; the middle half of products list 250 mg to 450 mg, the median 300 mg.450 mg

Higher than 69% of 338 products listing St. John's wort (median 300 mg). Per day at the most servings: 900 mg.

Hypericins1.35 mgHypericin in St. John's Wort 450 against 33 products1,350 mcg per serving; the middle half of products list 900 mcg to 1,800 mcg, the median 900 mcg.1,350 mcg

Higher than 61% of 33 products listing hypericin (median 900 mcg). Per day at the most servings: 2,700 mcg.

Source: NIH ODS Dietary Supplement Label Database, label 273078 (entered August 23, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: 1 tablet twice daily. To obtain the best results, use this product for at least 6 weeks.
Warnings
Do not use if either tamper-evident seal is broken or missing.
Keep out of the reach of children.
Warning: Do not use this product while taking any medication or if you have a medical condition, without the advice of your physician or pharmacist. St. John’s wort is known to interfere with many prescription and non-prescription drugs, including oral contraceptives, antibiotics, antidepressants, anticoagulants, antihistamines, immunosuppressants, corticosteroids, diabetes drugs, antiviral, antiseizure, anticancer and cardiovascular drugs.
It may also cause increased photosensitivity; limit exposure to UV radiation.
If you are pregnant, may become pregnant, or breastfeeding, consult your healthcare professional before using this product.
Allergens and what it does not contain
Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

Source: label statements in DSLD label 273078.

What else is on the label?

Other ingredients: Dibasic Calcium Phosphate, modified Cellulose Gum, Microcrystalline Cellulose, Stearic Acid, Silica, Magnesium Stearate.

How many labels does St. John's Wort 450 have?

4 labels are on file under this name since August 22, 2017: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 273078 (current) Entered August 23, 2022 · on the market · 180 tablets · UPC 0 21078 01177 4
  2. Label 77509 Entered August 22, 2017 · off the market December 22, 2021 · 180 tablets · UPC 0 21078 01177 4
  3. Label 77506 Entered August 22, 2017 · on the market · 90 tablets · UPC 0 21078 01176 7
  4. Label 77503 Entered August 22, 2017 · on the market · 45 tablets · UPC 0 21078 01175 0

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Source Naturals, Inc. (distributor), Santa Cruz, CA. All Source Naturals products.

Where next?