Milk Thistle Extract

by 21st Century · capsule · 200 vegetarian capsules

  • On the market (NIH)
  • UPC 7 40985 22907 1
  • DSLD label 326332
  • Serving 2 vegetarian capsules
  • 100 servings

Milk Thistle Extract by 21st Century lists one ingredient: 175 mg of milk thistle seed extract concentrate, powder per serving of 2 vegetarian capsules. Its current label entered the NIH Dietary Supplement Label Database on July 24, 2025.

What is in Milk Thistle Extract?

Each row as the label prints it, per serving of 2 vegetarian capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Milk Thistle Extract: Supplement Facts rows against the market (DSLD label 326332, January 2026 release)
IngredientAmount% DVAmong products listing it
Total Carbohydratesless than 1 g1%
Dietary Fiberless than 1 g2%
Milk Thistle Seed Extract Concentrate, Powderas Silybum marianum Seed Extract Concentrate, Powderstandardized concentrate of Silybum marianum175 mgMilk Thistle in Milk Thistle Extract against 1,277 products175 mg per serving; the middle half of products list 90 mg to 300 mg, the median 175 mg.175 mg

50% of 1,277 products listing milk thistle give more (median 175 mg).

Source: NIH ODS Dietary Supplement Label Database, label 326332 (entered July 24, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Milk Thistle Extract's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As an herbal supplement, adults take two (2) capsules daily with any meal or as directed by a healthcare provider.
Warnings
Do not exceed recommended dosage.
Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.
Stop use and contact a physician if adverse reactions occur.
Keep out of reach of children.
Do not use if product appears to be tampered with or seal is broken.
Allergens and what it does not contain
No added sugar, salt, yeast, preservatives, artificial flavors or colors.
Gluten Free | Non-GMO
Storage
Store at room temperature.

Source: label statements in DSLD label 326332.

What else is on the label?

Other ingredients: Cellulose, Starch, Magnesium Stearate, Silicon Dioxide.

How many labels does Milk Thistle Extract have?

7 labels are on file under this name since July 25, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 326332 (current) Entered July 24, 2025 · on the market · 200 vegetarian capsules · UPC 7 40985 22907 1
  2. Label 233575 Entered August 23, 2020 · off the market August 5, 2020 · 200 vegetarian capsules · UPC 7 40985 22907 1
  3. Label 233572 Entered August 23, 2020 · off the market August 5, 2020 · 60 vegetarian capsules · UPC 7 40985 21338 4
  4. Label 206602 Entered September 24, 2019 · off the market July 18, 2023 · 200 vegetarian capsules · UPC 7 40985 22907 1
  5. Label 205614 Entered August 23, 2019 · on the market · 60 vegetarian capsules · UPC 7 40985 21338 4
  6. Label 11470 Entered July 25, 2012 · off the market June 28, 2019 · 200 vegetarian capsules · UPC 7 40985 22907 1
  7. Label 11466 Entered July 25, 2012 · off the market June 28, 2019 · 60 vegetarian capsules · UPC 7 40985 21338 4

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names 21st Century HealthCare, Inc. (manufacturer), Tempe, AZ. All 21st Century products.

Where next?