Liver SafeGuard

by Rainbow Light · capsule · 50 vegetarian capsules

  • Off the market since March 2023 (NIH)
  • UPC 0 21888 81072 7
  • DSLD label 57174
  • Serving 1 to 2 capsules; amounts per 2 capsules
  • 25 servings

Liver SafeGuard by Rainbow Light lists 13 ingredients, 9 with an amount per serving of 2 capsules; 4 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on March 24, 2016.

What is in Liver SafeGuard?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Liver SafeGuard: Supplement Facts rows against the market (DSLD label 57174, January 2026 release)
IngredientAmount% DVAmong products listing it
Targeted Liver Support450 mg
Milk Thistle [seed, shell] extract300 mgMilk Thistle in Liver SafeGuard against 1,277 products300 mg per serving; the middle half of products list 90 mg to 300 mg, the median 175 mg.300 mg

Higher than 72% of 1,277 products listing milk thistle (median 175 mg).

Silymarin160 mgSilymarin in Liver SafeGuard against 208 products160 mg per serving; the middle half of products list 63.75 mg to 203 mg, the median 116 mg.160 mg

Higher than 61% of 208 products listing silymarin (median 116 mg).

Silybin Phospholipid Complex150 mgSilybin in Liver SafeGuard against 42 products150 mg per serving; the middle half of products list 57.6 mg to 195 mg, the median 132.5 mg.150 mg

Higher than 52% of 42 products listing silybin (median 132.5 mg).

Silybinas Milk ThistleSilybin (Form: from Milk Thistle PlantPart: fruit)50 mg
Total Phospholipidsas SoyTotal Phospholipids (Form: from Soy)100 mgPhospholipid in Liver SafeGuard against 257 products100 mg per serving; the middle half of products list 130 mg to 400 mg, the median 245 mg.100 mg

82% of 257 products listing phospholipid give more (median 245 mg).

Rejuvenating Liver Complex175 mg
N-Acetyl L-Cysteine100 mgN-Acetyl Cysteine in Liver SafeGuard against 1,259 products100 mg per serving; the middle half of products list 55 mg to 500 mg, the median 150 mg.100 mg

57% of 1,259 products listing N-acetyl cysteine give more (median 150 mg).

Curcuma longa [rhizome] extract50 mgTurmeric in Liver SafeGuard against 2,369 products50 mg per serving; the middle half of products list 50 mg to 500 mg, the median 150 mg.50 mg

71% of 2,369 products listing turmeric give more (median 150 mg).

Total Curcuminoids43 mgCurcuminoid in Liver SafeGuard against 309 products43 mg per serving; the middle half of products list 40 mg to 300 mg, the median 100 mg.43 mg

74% of 309 products listing curcuminoid give more (median 100 mg).

L-Glutathione25 mgGlutathione in Liver SafeGuard against 717 products25 mg per serving; the middle half of products list 10 mg to 200 mg, the median 50 mg.25 mg

57% of 717 products listing glutathione give more (median 50 mg).

Digestive Support BlendDigestive Support Blend Note: equivalent to 1,400 mg herbal powder200 mg
GingerGinger PlantPart: root Note: 10:1 fresh juicein the blend, no amount given
ArtichokeArtichoke PlantPart: leaf Note: 4:1 extractin the blend, no amount given
BurdockBurdock PlantPart: root Note: 4:1 extractin the blend, no amount given
Dandelion 4:1 extractin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 57174 (entered March 24, 2016), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 4 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Liver SafeGuard's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
SUGGESTED USAGE: Take 1 to 2 capsules daily with or between meals.
Warnings
KEEP OUT OF REACH OF CHILDREN.
Consult your health care professional prior to use if you are pregnant, nursing, taking medication or have a medical condition.
Allergens and what it does not contain
Contains NO: gluten, wheat, milk, tree nuts, peanuts, eggs, fish, or shellfish.
Gluten-Free / Stimulant-Free
Made with natural, purity-tested ingredients and NO artificial preservatives, colors, flavors or sweeteners.

Source: label statements in DSLD label 57174.

What else is on the label?

Other ingredients: Rice Flour, Microcrystalline Cellulose, Silica, Magnesium Stearate, Non-GMO Capsule.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): SILIPHOS.

How many labels does Liver SafeGuard have?

One label is on file, entered on March 24, 2016.

  1. Label 57174 (current) Entered March 24, 2016 · off the market March 28, 2023 · 50 vegetarian capsules · UPC 0 21888 81072 7

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Rainbow Light Nutritional Systems (manufacturer, distributor), Santa Cruz, CA. All Rainbow Light products.

Where next?