Liver and Organ Defender

by Rich Piana 5% Nutrition · capsule · 270 capsules

  • Off the market since November 2024 (NIH)
  • DSLD label 239986
  • Serving 3 capsules; amounts per 9 capsules
  • 30 servings

Liver and Organ Defender by Rich Piana 5% Nutrition lists 17 ingredients, 17 with an amount per serving of 9 capsules, such as 800 IU (20 mcg) of vitamin D, 30 mg of vitamin B6, 50 mg of magnesium and 30 mg of zinc. Its current label entered the NIH Dietary Supplement Label Database on November 21, 2020.

What is in Liver and Organ Defender?

Each row as the label prints it, per serving of 9 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Liver and Organ Defender: Supplement Facts rows against the market (DSLD label 239986, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Das CholecalciferolVitamin D (Form: as Cholecalciferol)800 IU (20 mcg)200%Vitamin D in Liver and Organ Defender against 14,175 products20 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg20 mcg

Higher than 51% of 14,175 products listing vitamin D (median 15 mcg). Per day at the most servings: 60 mcg.

Vitamin B6as Pyridoxine HydrochlorideVitamin B6 (Form: as Pyridoxine Hydrochloride)30 mg1,500%Vitamin B6 in Liver and Organ Defender against 15,277 products30 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg30 mg

Higher than 82% of 15,277 products listing vitamin B6 (median 6 mg). Per day at the most servings: 90 mg.

Magnesiumas DiMagnesium MalateMagnesium (Form: as DiMagnesium Malate)50 mg13%Magnesium in Liver and Organ Defender against 14,003 products50 mg per serving; the middle half of products list 30 mg to 200 mg, the median 86 mg.UL 350 mgDV 420 mg50 mg

59% of 14,003 products listing magnesium give more (median 86 mg). Per day at the most servings: 150 mg.

Zincas Zinc Bisglycinate ChelateZinc (Form: as Zinc Bisglycinate Chelate)30 mg200%Zinc in Liver and Organ Defender against 13,186 products30 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg30 mg

Higher than 90% of 13,186 products listing zinc (median 11 mg). Per day at the most servings: 90 mg. 2.3 times the adult UL a day.

Seleniumas Selenium GlycinateSelenium (Form: as Selenium Glycinate Complex)70 mcg100%Selenium in Liver and Organ Defender against 7,658 products70 mcg per serving; the middle half of products list 27 mcg to 100 mcg, the median 55 mcg.DV 55 mcgUL 400 mcg70 mcg

Higher than 52% of 7,658 products listing selenium (median 55 mcg). Per day at the most servings: 210 mcg.

Liver Supportno amount given
N-Acetyl L-Cysteine1,000 mgN-Acetyl Cysteine in Liver and Organ Defender against 1,259 products1,000 mg per serving; the middle half of products list 55 mg to 500 mg, the median 150 mg.1,000 mg

Higher than 96% of 1,259 products listing N-acetyl cysteine (median 150 mg). Per day at the most servings: 3,000 mg.

Milk Thistle powder600 mgMilk Thistle in Liver and Organ Defender against 1,277 products600 mg per serving; the middle half of products list 90 mg to 300 mg, the median 175 mg.600 mg

Higher than 92% of 1,277 products listing milk thistle (median 175 mg). Per day at the most servings: 1,800 mg.

L-Glutathione30 mgGlutathione in Liver and Organ Defender against 717 products30 mg per serving; the middle half of products list 10 mg to 200 mg, the median 50 mg.30 mg

54% of 717 products listing glutathione give more (median 50 mg). Per day at the most servings: 90 mg.

Heart Supportno amount given
Hawthorn Berry (Crataegus laevigata) fruit powder1,100 mgHawthorn in Liver and Organ Defender against 589 products1,100 mg per serving; the middle half of products list 75 mg to 400 mg, the median 200 mg.1,100 mg

Higher than 95% of 589 products listing hawthorn (median 200 mg). Per day at the most servings: 3,300 mg.

Alpha-Lipoic Acid400 mgAlpha Lipoic Acid in Liver and Organ Defender against 2,407 products400 mg per serving; the middle half of products list 25 mg to 150 mg, the median 50 mg.400 mg

Higher than 93% of 2,407 products listing alpha lipoic acid (median 50 mg). Per day at the most servings: 1,200 mg.

Garlic (Allium sativum L.) bulb extract300 mgGarlic in Liver and Organ Defender against 1,075 products300 mg per serving; the middle half of products list 50 mg to 500 mg, the median 200 mg.300 mg

Higher than 59% of 1,075 products listing garlic (median 200 mg). Per day at the most servings: 900 mg.

DiMagnesium Malate255 mgMagnesium Malate in Liver and Organ Defender against 57 products255 mg per serving; the middle half of products list 100 mg to 500 mg, the median 140 mg.255 mg

Higher than 68% of 57 products listing magnesium malate (median 140 mg). Per day at the most servings: 765 mg.

Ubidecarenoneas Co-Q1025 mgCoenzyme Q-10 in Liver and Organ Defender against 2,922 products25 mg per serving; the middle half of products list 30 mg to 100 mg, the median 60 mg.25 mg

77% of 2,922 products listing coenzyme Q-10 give more (median 60 mg). Per day at the most servings: 75 mg.

Prostate Supportno amount given
Saw Palmetto (Serenoa repens) powder1,000 mgSaw Palmetto in Liver and Organ Defender against 1,109 products1,000 mg per serving; the middle half of products list 100 mg to 320 mg, the median 200 mg.1,000 mg

Higher than 96% of 1,109 products listing saw palmetto (median 200 mg). Per day at the most servings: 3,000 mg.

Kidney Supportno amount given
Cordyceps sinensis500 mgCordyceps in Liver and Organ Defender against 450 products500 mg per serving; the middle half of products list 100 mg to 600 mg, the median 250 mg.500 mg

Higher than 64% of 450 products listing cordyceps (median 250 mg). Per day at the most servings: 1,500 mg.

Skin Supportno amount given
Zinc Bisglycinate Chelate300 mg
Selenium Glycinate Chelate7,000 mcg

Source: NIH ODS Dietary Supplement Label Database, label 239986 (entered November 21, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 3 servings a day, the most its directions give, the label lists 90 mg of zinc, 2.3 times the adult Tolerable Upper Intake Level.
  • Its 1,000 mg of N-acetyl L-cysteine (filed by NIH under N-acetyl cysteine) is higher than 96% of the 1,259 N-acetyl cysteine products that print an amount; 25 list more.
  • Its 600 mg of milk thistle is higher than 92% of the 1,277 milk thistle products that print an amount; 83 list more.
  • Its 1,100 mg of hawthorn is higher than 95% of the 589 hawthorn products that print an amount; 26 list more.
  • Its 400 mg of alpha-lipoic acid (filed by NIH under alpha lipoic acid) is higher than 93% of the 2,407 alpha lipoic acid products that print an amount; 137 list more.
  • Its 1,000 mg of saw palmetto is higher than 96% of the 1,109 saw palmetto products that print an amount; 24 list more.

The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Liver and Organ Defender's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
What are the suggested directions for using Liver and Organ Defender? Take 3 capsules with your first meal of the day, 3 capsules with a mid-afternoon meal and 3 capsules with your last meal of the day.
Warnings
Always consult with a qualified healthcare professional prior to beginning any diet or exercise program or taking any dietary supplement. The content on our website is for informational and educational purposes only and is not intended as medical advice or to replace a relationship with a qualified healthcare professional.

Source: label statements in DSLD label 239986.

What else is on the label?

Other ingredients: Gelatin, Cellulose, Plant, Magnesium Stearate, Silicon Dioxide.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GMP Good Manufacturing Practices.

How many labels does Liver and Organ Defender have?

One label is on file, entered on November 21, 2020.

  1. Label 239986 (current) Entered November 21, 2020 · off the market November 18, 2024 · 270 capsules

DSLD also links this label to: Liver & Organ Defender (image difference, same product), Liver & Organ Defender (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Rich Piana 5% Nutrition (manufacturer). All Rich Piana 5% Nutrition products.

Where next?