Hydraplenish with OptiMSM

by Nature's Way · capsule · 60 capsules

  • On the market (NIH)
  • UPC 0 33674 15603 2
  • DSLD label 327985
  • Serving 2 capsules
  • 30 servings

Hydraplenish with OptiMSM by Nature's Way lists 2 ingredients, 2 with an amount per serving of 2 capsules, such as 1 g of BioCell collagen and 500 mg of OptiMSM, beside 2 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on May 21, 2025.

What is in Hydraplenish with OptiMSM?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Hydraplenish with OptiMSM: Supplement Facts rows against the market (DSLD label 327985, January 2026 release)
IngredientAmount% DVAmong products listing it
Proteinless than 1 g2%
Sodium15 mg1%Sodium in Hydraplenish with OptiMSM against 14,514 products15 mg per serving; the middle half of products list 15 mg to 142 mg, the median 55 mg.15 mg

72% of 14,514 products listing sodium give more (median 55 mg). Per day at the most servings: 30 mg.

BioCell Collagenas Chicken Sternal Cartilage Extract, Hydrolyzed1 gCollagen in Hydraplenish with OptiMSM against 1,008 products1 g per serving; the middle half of products list 0.1 g to 4.2 g, the median 1 g.1 g

44% of 1,008 products listing collagen give more (median 1 g). Per day at the most servings: 2 g.

OptiMSMas Methylsulfonylmethane500 mgMethylsulfonylmethane in Hydraplenish with OptiMSM against 1,454 products500 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.500 mg

36% of 1,454 products listing methylsulfonylmethane give more (median 500 mg). Per day at the most servings: 1,000 mg.

Source: NIH ODS Dietary Supplement Label Database, label 327985 (entered May 21, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 1 to 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Hydraplenish with OptiMSM's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendation: Adults take 2 capsules, 1-2 times daily.
Warnings
Keep out of reach of children.
Safety sealed with inner seal. Do not use if seal is broken or missing.
If you are pregnant, nursing, or taking any medications, consult a healthcare professional before use.
Storage
Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Source: label statements in DSLD label 327985.

What else is on the label?

Other ingredients: Hypromellose, Magnesium Stearate.

How many labels does Hydraplenish with OptiMSM have?

One label is on file, entered on May 21, 2025.

  1. Label 327985 (current) Entered May 21, 2025 · on the market · 60 capsules · UPC 0 33674 15603 2

DSLD also links this label to: Hydraplenish Plus MSM (package size difference, same product), Hydraplenish Plus MSM (image difference, same product), Hydraplenish Plus MSM (package size difference, same product), Hydraplenish With MSM (package size difference, same product), Hydraplenish With MSM (image difference, same product), Hydraplenish With MSM (package size difference, same product), Hydraplenish (package size difference, same product), Hydraplenish (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature's Way Brands, LLC (manufacturer), Green Bay, WI. All Nature's Way products.

Where next?