PlainVitamins

Hydraplenish Plus MSM

by Nature's Way · capsule · 60 vcaps(R)

  • Off the market since May 2017 (NIH)
  • UPC 0 33674 15603 2
  • DSLD label 39985
  • Serving 2 to 4 capsules; amounts per 2 capsules
  • 30 servings

Hydraplenish Plus MSM by Nature's Way lists 5 ingredients, 5 with an amount per serving of 2 capsules, such as 500 mg of MSM, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on November 25, 2014.

What is in Hydraplenish Plus MSM?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Hydraplenish Plus MSM: Supplement Facts rows against the market (DSLD label 39985, January 2026 release)
IngredientAmount% DVAmong products listing it
Proteinless than 1 g1%
BioCell CollagenBioCell Collagen Note: (1,000 mg) (providing)1 gCollagen Peptides in Hydraplenish Plus MSM against 395 products1 g per serving; the middle half of products list 2.5 g to 11 g, the median 6 g.1 g

84% of 395 products listing collagen peptides give more (median 6 g).

Hydrolyzed Collagen Type II600 mgCollagen in Hydraplenish Plus MSM against 1,008 products0.6 g per serving; the middle half of products list 0.1 g to 4.2 g, the median 1 g.0.6 g

55% of 1,008 products listing collagen give more (median 1 g).

Chondroitin Sulfate200 mgChondroitin Sulfate in Hydraplenish Plus MSM against 950 products200 mg per serving; the middle half of products list 200 mg to 1,200 mg, the median 400 mg.200 mg

66% of 950 products listing chondroitin sulfate give more (median 400 mg).

Hyaluronic Acid100 mgHyaluronic acid in Hydraplenish Plus MSM against 900 products100 mg per serving; the middle half of products list 10 mg to 100 mg, the median 50 mg.100 mg

Higher than 64% of 900 products listing hyaluronic acid (median 50 mg).

MSMas OptiMSM(R)MSM (Form: as OptiMSM(R)) (Alt. Name: Methylsulfonylmethane) Note: 1,000 mg500 mgMethylsulfonylmethane in Hydraplenish Plus MSM against 1,454 products500 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.500 mg

36% of 1,454 products listing methylsulfonylmethane give more (median 500 mg).

Source: NIH ODS Dietary Supplement Label Database, label 39985 (entered November 25, 2014), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Hydraplenish Plus MSM's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendation: Take 2 capsules daily. For intensive use: Take 4 capsules daily.
Warnings
Double safety sealed with printed outer shrinkwrap film and printed inner bottle freshness seal. Do not use if either seal is broken or missing.
Keep out of reach of children.
Caution: If pregnant or lactating, consult your healthcare professional before taking this product.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 39985.

What else is on the label?

Other ingredients: plant-derived Capsule, Magnesium Stearate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): BioCell Collagen(R).

How many labels does Hydraplenish Plus MSM have?

2 labels are on file under this name since November 25, 2014: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 39985 (current) Entered November 25, 2014 · off the market May 24, 2017 · 60 vcaps(R) · UPC 0 33674 15603 2
  2. Label 39983 Entered November 25, 2014 · off the market May 24, 2017 · 30 vcaps(R) · UPC 0 33674 15602 5

DSLD also links this label to: Hydraplenish With MSM (package size difference, same product), Hydraplenish With MSM (image difference, same product), Hydraplenish With MSM (package size difference, same product), Hydraplenish (package size difference, same product), Hydraplenish (image difference, same product), Hydraplenish (package size difference, same product), Hydraplenish (package size difference, same product), Hydraplenish (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature's Way Products, LLC (manufacturer), Green Bay, WI. All Nature's Way products.

Where next?