GugulPlus

by Enzymatic Therapy · tablet or pill · 90 tablets

  • Off the market since June 2017 (NIH)
  • UPC 7 63948 08609 2
  • DSLD label 25199
  • Serving 1 tablet

GugulPlus by Enzymatic Therapy lists 5 ingredients, 5 with an amount per serving of 1 tablet, such as 100 mg of vitamin C, 250 mg of niacin, 50 mcg of chromium and 250 mg of guggul (commiphora mukul) gum extract, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on September 25, 2013.

What is in GugulPlus?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

GugulPlus: Supplement Facts rows against the market (DSLD label 25199, January 2026 release)
IngredientAmount% DVAmong products listing it
Total Carbohydratesless than 1 g1%
Vitamin Cas Potassium AscorbateVitamin C (Form: as Potassium Ascorbate)100 mg167%Vitamin C in GugulPlus against 18,583 products100 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg100 mg

50% of 18,583 products listing vitamin C give more (median 100 mg).

Niacinas Inositol HexanicotinateNiacin (Form: as inositol hexaniacinate) Note: Enzymatic Therapy's niacin is flush-free.250 mg1,250%Niacin in GugulPlus against 12,413 products250 mg per serving; the middle half of products list 13.2 mg to 48 mg, the median 20 mg.DV 16 mgUL 35 mg250 mg

Higher than 96% of 12,413 products listing niacin (median 20 mg). 7.1 times the adult UL a day.

Chromiumas Chromium PolynicotinateChromium (Form: as chromium polynicotinate) (Alt. Name: ChromeMate(R) brand) Note: Patented niacin-bound GTF chromium50 mcg42%Chromium in GugulPlus against 7,825 products50 mcg per serving; the middle half of products list 45 mcg to 200 mcg, the median 100 mcg.DV 35 mcg50 mcg

67% of 7,825 products listing chromium give more (median 100 mcg).

Guggul (Commiphora mukul) Gum Extractas guggulsteronesGuggul (Commiphora mukul) Gum Extract (Form: standardized to contain 2.5% guggulsterones Note: 25 mg per g) PlantPart: Gum Genus: Commiphora Species: mukul250 mgGuggul in GugulPlus against 279 products250 mg per serving; the middle half of products list 50 mg to 350 mg, the median 100 mg.250 mg

Higher than 67% of 279 products listing guggul (median 100 mg).

Ginger (Zingiber officinale) rhizome extract200 mgGinger in GugulPlus against 1,770 products200 mg per serving; the middle half of products list 25 mg to 150 mg, the median 60 mg.200 mg

Higher than 77% of 1,770 products listing ginger (median 60 mg).

Source: NIH ODS Dietary Supplement Label Database, label 25199 (entered September 25, 2013), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • At 1 serving a day, the most its directions give, the label lists 250 mg of niacin, 7.1 times the adult Tolerable Upper Intake Level.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with GugulPlus's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Warnings
If pregnant, nursing, taking prescription drugs, have gallstones or bile duct obstruction, consult your healthcare practitioner prior to use.
Storage
Recommendations: One tablet three times daily.

Source: label statements in DSLD label 25199.

What else is on the label?

Other ingredients: Cellulose, Modified Cellulose, Stearic Acid, modified Cellulose Gum, Magnesium Stearate, Titanium Dioxide color, Silicon Dioxide, Soy Lecithin, Vegetable Glycerin, Carnauba Wax.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): LABORATORY TESTED PURITY, SAFETY & PERFORMANCE; VEGETARIAN; Enzymatic Therapy What Better Feels Like(R).

How many labels does GugulPlus have?

One label is on file, entered on September 25, 2013.

  1. Label 25199 (current) Entered September 25, 2013 · off the market June 12, 2017 · 90 tablets · UPC 7 63948 08609 2

DSLD also links this label to: GugulPlex (package size difference, same product), GugulPlex (image difference, same product), GugulPlex (package size difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Enzymatic Therapy, Inc. (manufacturer), Green Bay, WI. All Enzymatic Therapy products.

Where next?