GugulPlex
by Enzymatic Therapy · tablet or pill · 90 tablets
- Off the market since August 2023 (NIH)
- UPC 7 63948 08609 2
- DSLD label 77827
- Serving 1 tablet
GugulPlex by Enzymatic Therapy lists 4 ingredients, 4 with an amount per serving of 1 tablet, such as 100 mg of vitamin C, 250 mg of niacin, 250 mg of guggul gum extract and 200 mg of ginger rhizome extract, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on August 22, 2017.
What is in GugulPlex?
Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).
| Ingredient | Amount | % DV | Among products listing it |
|---|---|---|---|
| Dietary Fiber | less than 1 g | 2% | |
| Vitamin Cas Potassium AscorbateVitamin C (Form: as Potassium Ascorbate) | 100 mg | 167% | 50% of 18,583 products listing vitamin C give more (median 100 mg). Per day at the most servings: 300 mg. |
| Niacinas Inositol HexanicotinateNiacin (Form: as Inositol Hexaniacinate) | 250 mg | 1,250% | Higher than 96% of 12,413 products listing niacin (median 20 mg). Per day at the most servings: 750 mg. 21.4 times the adult UL a day. |
| Guggul gum extractas GuggulsteronesGuggul gum extract (Form: standardized to 2.5% Guggulsterones Note: 6.25 mg) PlantPart: gum | 250 mg | Higher than 67% of 279 products listing guggul (median 100 mg). Per day at the most servings: 750 mg. | |
| Ginger rhizome extract | 200 mg | Higher than 77% of 1,770 products listing ginger (median 60 mg). Per day at the most servings: 600 mg. |
Source: NIH ODS Dietary Supplement Label Database, label 77827 (entered August 22, 2017), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.
Is that a lot?
The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:
- At 3 servings a day, the most its directions give, the label lists 750 mg of niacin, 21.4 times the adult Tolerable Upper Intake Level.
The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.
The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.
Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.
Which products have the closest formulas?
1 product lists the very same ingredients; the nearest amounts come first.
- GugulplexIntegrative Therapeutics same ingredients
- GugulPlusEnzymatic Therapy · off the market 4 shared, 65% alike
- GuggulXtraDC 3 shared, 54% alike
- Guggul 250Wonder Laboratories 3 shared, 54% alike
- LipotainMetagenics 2 shared, 51% alike
- Guggulipid Standardized Extract 250 mgMartin Avenue Pharmacy 1 shared, 36% alike
Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.
What does the label say about taking it?
Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.
- Directions
- Recommendation: Take 1 tablet three times daily.
- Warnings
- Caution: Do not use if pregnant.
- If nursing or taking any medications, consult a healthcare professional before use.
- Keep out of reach of children.
- Safety sealed with printed outer shrinkwrap and inner seal. Do not use if either is broken or missing.
- Contains soy.
- Do not exceed recommended dosage per day.
- Allergens and what it does not contain
- Gluten free. No sugar, salt, yeast, wheat, dairy products, artificial flavors or preservatives.
Source: label statements in DSLD label 77827.
What else is on the label?
Other ingredients: Cellulose, Stearic Acid, Modified Cellulose, modified Cellulose Gum, Magnesium Stearate, Titanium Dioxide color, Silicon Dioxide, Soy Lecithin, Vegetable Glycerin, Carnauba Wax.
How many labels does GugulPlex have?
2 labels are on file under this name since October 22, 2016: other sizes, label designs and reformulations. The current one leads this page.
- Label 77827 (current) Entered August 22, 2017 · off the market August 10, 2023 · 90 tablets · UPC 7 63948 08609 2
- Label 65512 Entered October 22, 2016 · off the market August 10, 2023 · 45 tablets · UPC 7 63948 08604 7
DSLD also links this label to: GugulPlus (image difference, same product), GugulPlus (package size difference, same product).
Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).
Who makes it?
The label names Enzymatic Therapy, LLC (part of Nature's Way Brands, LLC) (manufacturer), Green Bay, WI. All Enzymatic Therapy products.