Gluten Defense

by Nature's Way · capsule · 120 vegan capsules

  • On the market (NIH)
  • UPC 7 63948 03952 4
  • DSLD label 327974
  • Serving 2 capsules
  • 60 servings

Gluten Defense by Nature's Way lists 7 ingredients; 6 give their count of live cultures or enzyme activity instead of a weight; 1 sits inside a blend without its own amount. Its current label entered the NIH Dietary Supplement Label Database on April 24, 2025.

What is in Gluten Defense?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Gluten Defense: Supplement Facts rows against the market (DSLD label 327974, January 2026 release)
IngredientAmount% DVAmong products listing it
Microbial Enzymes621 mg
DPP IV Protease Blendas ProteaseAssay Method FCC (pH 4.7) 134,660 HUT, FCC (pH 7.0) 22,660 PC, USP (pH 7.5) 12,557 USP
AmylaseAssay Method FCC (pH 4.6) 16,370 DP, FCC (pH 4.8) 16,370 DU, USP (pH 6.8) 10,913 USP
Lactaseas Lactase I, Lactase IIFCC (pH 4.5) 642 ALU
Lipaseas Lipase I, Lipase IIFCC (pH 7.0) 888 FIP
Cellulaseas Cellulase I, Cellulase IIFCC (pH 4.5) 141 CU
Sucraseas InvertaseFCC (pH 4.5) 181 SU
PhytaseFCC (pH 5.5) 0.68 FTUin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 327974 (entered April 24, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 7 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

1 product lists the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendation: Adults take 2 capsules with each meal or as recommended by a healthcare professional.
Warnings
Caution: If you are pregnant, nursing, have diabetes, or if you are taking any medications, consult a healthcare professional before use.
While gluten defense with reduce the level of reactive gliadin and gluten proteins in a meal, it is advised that celiac disease sufferers continue with their normal gluten-exclusion diet as even small amounts of gliadin can cause adverse reactions in the most sensitive individuals.
Keep out of reach of children.
Safety sealed with inner seal. Do not use if seal is broken or missing.
Allergens and what it does not contain
Vegan V Gelatin Free
Contains no dairy, gelatin, or artificial colors or flavors.
Storage
Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Source: label statements in DSLD label 327974.

What else is on the label?

Other ingredients: Hypromellose, Cellulose, Inulin, Calcium Laurate, Silica.

How many labels does Gluten Defense have?

5 labels are on file under this name since February 26, 2020: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 327974 (current) Entered April 24, 2025 · on the market · 120 vegan capsules · UPC 7 63948 03952 4
  2. Label 267833 Entered June 16, 2022 · off the market December 20, 2024 · 120 vegan capsules · UPC 7 63948 03952 4
  3. Label 230225 Entered July 23, 2020 · off the market September 30, 2021 · 120 vegan capsules · UPC 7 63948 03952 4
  4. Label 213984 Entered March 24, 2020 · off the market March 11, 2022 · 120 vegan capsules · UPC 7 63948 03952 4
  5. Label 213831 Entered February 26, 2020 · on the market · 60 vegetarian capsules · UPC 0 33674 12719 3

DSLD also links this label to: QUICKMASS Chocolate Peanut Butter (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature's Way Brands, LLC (distributor), Green Bay, WI. All Nature's Way products.

Where next?