Similase

by Integrative Therapeutics · capsule · 180 capsules

  • On the market (NIH)
  • UPC 8 71791 00059 9
  • DSLD label 251228
  • Serving 2 capsules
  • 90 servings

Similase by Integrative Therapeutics lists 7 ingredients; 6 give their count of live cultures or enzyme activity instead of a weight; 1 sits inside a blend without its own amount. Its current label entered the NIH Dietary Supplement Label Database on June 23, 2021.

What is in Similase?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Similase: Supplement Facts rows against the market (DSLD label 251228, January 2026 release)
IngredientAmount% DVAmong products listing it
Microbial Enzymes563 mg
AmylaseAmylase Note: Assay Method: USP (pH 6.8) 21,288 USP FCC (pH 4.8) 31,932 DU FCC (pH 4.6) 31,932 DP
Proteaseas Protease I, Protease II, Protease IIIProtease I, II, III, IV Note: Assay Method USP (pH 7.5) 31,394 USP FCC (pH 7.0) 56,653 PC FCC (pH 4.7) 82,000 HUT
Lactaseas Lactase I, Lactase IILactase I, II Note: Assay Method FCC (pH 4.5) 1,600 ALU
Lipaseas Lipase I, Lipase IILipase I, II Note: Assay Method: FCC (pH 7.0) 2,200 FIP
Cellulaseas Cellulase I, Cellulase IICellulase I, II Note: Assay Method FCC (pH 4.5) 350 CU
Sucraseas InvertaseSucrase (Form: Invertase) Note: Assay Method: FCC (pH 4.5) 936 SU
PhytasePhytase Note: Assay Method: FCC (pH 5.5) 1.7 FTUin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 251228 (entered June 23, 2021), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 7 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records 1 to 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

2 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Keep tightly closed.
Recommendation: Adults take 2 capsules at the beginning of each meal, up to 3 times daily, or as recommended by a healthcare professional.
Warnings
Caution: If you are pregnant, nursing, have diabetes, or if you are taking prescription drugs, consult your healthcare professional before use.
Keep out of reach of children.
Safety sealed with inner seal. Do not use if seal is broken or missing
Allergens and what it does not contain
Contains no dairy, or artificial colors, flavors, or preservatives.
Storage
Store at room temperature. Avoid excessive heat and direct sunlight.

Source: label statements in DSLD label 251228.

What else is on the label?

Other ingredients: plant-derived Capsule, Cellulose, Magnesium Stearate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Quality Global Sourcing Bottled & Tested In The USA.

How many labels does Similase have?

8 labels are on file under this name since January 25, 2017: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 251228 (current) Entered June 23, 2021 · on the market · 180 capsules · UPC 8 71791 00059 9
  2. Label 251221 Entered June 23, 2021 · on the market · 90 capsules · UPC 8 71791 00060 5
  3. Label 223473 Entered June 24, 2020 · off the market April 6, 2021 · 180 veg capsules · UPC 8 71791 00059 9
  4. Label 223412 Entered June 24, 2020 · off the market April 6, 2021 · 90 veg capsules · UPC 8 71791 00060 5
  5. Label 223135 Entered June 24, 2020 · off the market February 28, 2020 · 180 veg capsules · UPC 8 71791 00059 9
  6. Label 223129 Entered June 24, 2020 · off the market February 28, 2020 · 90 veg capsules · UPC 8 71791 00060 5
  7. Label 76958 Entered September 21, 2017 · off the market January 15, 2020 · 90 veg capsules · UPC 8 71791 00060 5
  8. Label 69603 Entered January 25, 2017 · off the market January 15, 2020 · 180 veg capsules · UPC 8 71791 00059 9

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Integrative Therapeutics, LLC (distributor), Green Bay, WI. All Integrative Therapeutics products.

Where next?