Glucosamine & Chondroitin plus Hyaluronic Acid + MSM

by 21st Century · tablet or pill · 120 tablets

  • On the market (NIH)
  • UPC 7 40985 27387 6
  • DSLD label 207477
  • Serving 1 tablet; amounts per 3 tablets
  • 40 servings

Glucosamine & Chondroitin plus Hyaluronic Acid + MSM by 21st Century lists 5 ingredients, 3 with an amount per serving of 3 tablets, such as 1,500 mg of glucosamine HCl, 1,200 mg of chondroitin sulfate and 500 mg of MSM; 2 sit inside a blend without their own amounts, beside 3 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on September 24, 2019.

What is in Glucosamine & Chondroitin plus Hyaluronic Acid + MSM?

Each row as the label prints it, per serving of 3 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Glucosamine & Chondroitin plus Hyaluronic Acid + MSM: Supplement Facts rows against the market (DSLD label 207477, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories10 Calories
Total Carbohydrates2 g1%Carbohydrate in Glucosamine & Chondroitin plus Hyaluronic Acid + MSM against 21,979 products2 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.2 g

58% of 21,979 products listing carbohydrate give more (median 3 g). Per day at the most servings: 6 g.

Total Sugars1 gSugar in Glucosamine & Chondroitin plus Hyaluronic Acid + MSM against 11,807 products1 g per serving; the middle half of products list 1 g to 4 g, the median 2 g.1 g

69% of 11,807 products listing sugar give more (median 2 g). Per day at the most servings: 3 g.

Sodium120 mg6%Sodium in Glucosamine & Chondroitin plus Hyaluronic Acid + MSM against 14,514 products120 mg per serving; the middle half of products list 15 mg to 142 mg, the median 55 mg.120 mg

Higher than 69% of 14,514 products listing sodium (median 55 mg). Per day at the most servings: 360 mg.

Glucosamine HCl1,500 mgGlucosamine Hydrochloride in Glucosamine & Chondroitin plus Hyaluronic Acid + MSM against 628 products1.5 g per serving; the middle half of products list 0.75 g to 1.5 g, the median 1.5 g.1.5 g

5% of 628 products listing glucosamine hydrochloride give more (median 1.5 g). Per day at the most servings: 4.5 g.

Chondroitin Sulfate1,200 mgChondroitin Sulfate in Glucosamine & Chondroitin plus Hyaluronic Acid + MSM against 950 products1,200 mg per serving; the middle half of products list 200 mg to 1,200 mg, the median 400 mg.1,200 mg

Higher than 74% of 950 products listing chondroitin sulfate (median 400 mg). Per day at the most servings: 3,600 mg.

MSM500 mgMethylsulfonylmethane in Glucosamine & Chondroitin plus Hyaluronic Acid + MSM against 1,454 products500 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.500 mg

36% of 1,454 products listing methylsulfonylmethane give more (median 500 mg). Per day at the most servings: 1,500 mg.

Proprietary Blend60 mg
Silicain the blend, no amount given
Hyaluronic Acidas Sodium HyaluronateHyaluronic Acid (Form: as Sodium Hyaluronate)in the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 207477 (entered September 24, 2019), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 2 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records 1 to 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Glucosamine & Chondroitin plus Hyaluronic Acid + MSM's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As a dietary supplement, adults take one (1) tablet with any meal, up to three (3) times daily or as directed by a healthcare provider. Do not exceed recommended dosage.
Warnings
Do not exceed recommended dosage.
Warning: If you are diabetic, consult your physician before using this product.
If you have a Shellfish allergy, please consult your physician before using this product.
Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.
Stop use and contact a physician if adverse reactions occur.
Keep out of reach of children.
Do not use if product appears to be tampered with or seal is broken.
Contains shellfish (shrimp, crab, crayfish).
Allergens and what it does not contain
No added Sugar, Yeast, Preservatives or Artificial Flavors. Gluten Free.
Storage
Store at room temperature.

Source: label statements in DSLD label 207477.

What else is on the label?

Other ingredients: Cellulose, Polyplasdone, Stearic Acid, Contains <2% of.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Guaranteed quality Laboratory tested.

How many labels does Glucosamine & Chondroitin plus Hyaluronic Acid + MSM have?

2 labels are on file under this name since March 25, 2015: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 207477 (current) Entered September 24, 2019 · on the market · 120 tablets · UPC 7 40985 27387 6
  2. Label 43707 Entered March 25, 2015 · off the market March 14, 2019 · 120 easy to swallow tablets · UPC 7 40985 27387 6

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names 21st Century HealthCare, Inc. (manufacturer), Tempe, AZ. All 21st Century products.

Where next?