Formula 416 Protease + Calcium

by NESS Nutritional Enzyme Support System · capsule · 90 vegetarian capsules

  • On the market (NIH)
  • UPC 7 07636 03352 4
  • DSLD label 221305
  • Serving 4 vegetarian capsules
  • 22 servings

Formula 416 Protease + Calcium by NESS Nutritional Enzyme Support System lists 4 ingredients, 1 with an amount per serving of 4 vegetarian capsules, such as 60 mg of calcium; 3 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on May 22, 2020.

What is in Formula 416 Protease + Calcium?

Each row as the label prints it, per serving of 4 vegetarian capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Formula 416 Protease + Calcium: Supplement Facts rows against the market (DSLD label 221305, January 2026 release)
IngredientAmount% DVAmong products listing it
Calciumas Calcium LactateCalcium (Form: as Calcium Lactate)60 mg5%Calcium in Formula 416 Protease + Calcium against 17,831 products60 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg60 mg

68% of 17,831 products listing calcium give more (median 115 mg).

Proprietary Enzyme Blend609 mg
Proteasein the blend, no amount given
Amylasein the blend, no amount given
Lipasein the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 221305 (entered May 22, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 3 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommended Use: Take four (4) capsules one or more times daily on an empty stomach, or as directed by your healthcare professional.
Warnings
Caution: If you are pregnant, nursing, have a serious medical condition, or take any medications, consult your physician before use.
Use only if tamper evident seal is unbroken.
Keep out of reach of children.
Allergens and what it does not contain
Non-GMO
Contains No: Aspartame, sugar, salt, gluten, artificial colors or flavors, dairy products, wheat, soy, yeast or corn proteins.
Storage
Store tightly closed in a cool, dry place.

Source: label statements in DSLD label 221305.

What else is on the label?

Other ingredients: Plant Fiber, Water.

How many labels does Formula 416 Protease + Calcium have?

2 labels are on file under this name since May 22, 2020: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 221305 (current) Entered May 22, 2020 · on the market · 90 vegetarian capsules · UPC 7 07636 03352 4
  2. Label 221304 Entered May 22, 2020 · on the market · 180 vegetarian capsules · UPC 7 07636 03353 1

DSLD also links this label to: Formula 416 Protease W/Calcium (image difference, same product), Formula 416 Protease W/Calcium (package size difference, same product), Formula 416 Protease W/Calcium (package size difference, same product), Formula 416 Protease W/Calcium (image difference, same product), Formula 416 Protease W/Calcium (package size difference, same product), Formula 416 Protease W/Calcium (package size difference, same product), Formula 416 Protease w/ Calcium (package size difference, same product), Formula 416 Protease w/ Calcium (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Enzymes Inc. (manufacturer), Kansas City, MO, U.S.A.. All NESS Nutritional Enzyme Support System products.

Where next?