PlainVitamins

Formula 4 Protease

by NESS Nutritional Enzyme Support System · capsule · 180 vegetarian capsules

  • On the market (NIH)
  • UPC 7 07636 03142 1
  • DSLD label 221225
  • Serving 1 vegetarian capsule
  • 180 servings

Formula 4 Protease by NESS Nutritional Enzyme Support System lists one ingredient: 193 mg of protease per serving of 1 vegetarian capsule. Its current label entered the NIH Dietary Supplement Label Database on May 22, 2020.

What is in Formula 4 Protease?

Each row as the label prints it, per serving of 1 vegetarian capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Formula 4 Protease: Supplement Facts rows against the market (DSLD label 221225, January 2026 release)
IngredientAmount% DVAmong products listing it
Protease193 mgProteolytic Enzymes (Proteases) in Formula 4 Protease against 327 products193 mg per serving; the middle half of products list 10 mg to 100 mg, the median 30 mg.193 mg

Higher than 88% of 327 products listing proteolytic enzymes (proteases) (median 30 mg).

Source: NIH ODS Dietary Supplement Label Database, label 221225 (entered May 22, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommended Use: Take one (1) capsule at the beginning of each meal for digestive support or twice daily on an empty stomach for systemic support, or as directed by your healthcare professional.
Warnings
Caution: If you are pregnant, nursing, have a serious medical condition, or take any medications, consult your physician before use.
Use only if tamper evident seal is unbroken.
Keep out of reach of children.
Allergens and what it does not contain
Non-GMO
Contains No: Aspartame, sugar, salt, gluten, artificial colors or flavors, dairy products, wheat, soy, yeast or corn proteins.
Storage
Store tightly closed in a cool, dry place.

Source: label statements in DSLD label 221225.

What else is on the label?

Other ingredients: Plant Fiber, Water.

How many labels does Formula 4 Protease have?

6 labels are on file under this name since April 26, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 221225 (current) Entered May 22, 2020 · on the market · 180 vegetarian capsules · UPC 7 07636 03142 1
  2. Label 221220 Entered May 22, 2020 · on the market · 90 vegetarian capsules · UPC 7 07636 03141 4
  3. Label 37566 Entered October 10, 2014 · off the market January 28, 2020 · 180 vegetarian capsules
  4. Label 37565 Entered October 10, 2014 · off the market January 28, 2020 · 90 vegetarian capsules
  5. Label 7475 Entered April 26, 2012 · off the market February 11, 2014 · 180 capsules · UPC 7 07636 03142 1
  6. Label 7472 Entered April 26, 2012 · off the market February 11, 2014 · 90 capsules · UPC 7 07636 03141 4

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Enzymes Inc. (manufacturer), Kansas City, MO, U.S.A.. All NESS Nutritional Enzyme Support System products.

Where next?