Estrotone

by New Chapter · capsule · 60 vegetarian capsules

  • On the market (NIH)
  • DSLD label 288194
  • Serving 1 capsule
  • 60 servings

Estrotone by New Chapter lists 8 ingredients, 8 with an amount per serving of 1 capsule, such as 200 mg of evening primrose oil supercritical seed extract, 160 mg of schizandra hydroethanolic extract, 50 mg of ginger and 40 mg of black cohosh hydroethanolic extract. Its current label entered the NIH Dietary Supplement Label Database on June 22, 2023.

What is in Estrotone?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Estrotone: Supplement Facts rows against the market (DSLD label 288194, January 2026 release)
IngredientAmount% DVAmong products listing it
Evening Primrose Oil Supercritical Seed Extract200 mgEvening Primrose oil in Estrotone against 300 products200 mg per serving; the middle half of products list 500 mg to 1,300 mg, the median 500 mg.200 mg

87% of 300 products listing evening primrose oil give more (median 500 mg).

Schizandra hydroethanolic extract160 mgSchisandra in Estrotone against 460 products160 mg per serving; the middle half of products list 50 mg to 240 mg, the median 108.75 mg.160 mg

Higher than 59% of 460 products listing schisandra (median 108.75 mg).

Ginger50 mgGinger in Estrotone against 1,770 products50 mg per serving; the middle half of products list 25 mg to 150 mg, the median 60 mg.50 mg

51% of 1,770 products listing ginger give more (median 60 mg).

Ginger Supercritical Rhizome ExtractOrganic27 mg
Ginger Rhizome Extract, Aqueous23 mg
Black Cohosh Hydroethanolic Extractas Black Cohosh Root Hydroethanolic Extract, Black Cohosh Rhizome Hydroethanolic Extract40 mgBlack Cohosh in Estrotone against 431 products40 mg per serving; the middle half of products list 40 mg to 160 mg, the median 80 mg.40 mg

68% of 431 products listing black cohosh give more (median 80 mg).

Chaste Tree Berry Hydroethanolic Extractas Aucubin40 mgChastetree in Estrotone against 386 products40 mg per serving; the middle half of products list 50 mg to 240 mg, the median 100 mg.40 mg

79% of 386 products listing chastetree give more (median 100 mg).

Rosemary Leaf Supercritical Extract10 mgRosemary in Estrotone against 332 products10 mg per serving; the middle half of products list 25 mg to 100 mg, the median 50 mg.10 mg

81% of 332 products listing rosemary give more (median 50 mg).

Source: NIH ODS Dietary Supplement Label Database, label 288194 (entered June 22, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Estrotone's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: One Capsule Daily With Food.
Warnings
Not recommended for use in children.
Caution: Contact a healthcare professional prior to use if taking birth control, planning surgery, have a pre-existing liver disorder, history of cancer or pituitary disorders. Do not use if pregnant, nursing, considering pregnancy, or taking contraceptives.
Discontinue use and consult a healthcare professional if you develop symptoms of liver trouble, such as abdominal pain, dark urine, or jaundice.
Keep out of reach of children.
Read ingredients carefully and avoid use if known sensitivity to any ingredient.
Allergens and what it does not contain
Certified Gluten-Free by NSF; 100% vegetarian; no artificial flavors or colors.
Non GMO

Source: label statements in DSLD label 288194.

What else is on the label?

Other ingredients: extra-virgin Olive Oil, Hypromellose, Yellow Beeswax, Candelilla Wax.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Non GMO Project Verified nongmoproject.org NSF Certified Gluten-free Certified B Corporation. Listed with: Certified gluten-free (GFCO), NSF certified (contents or GMP) (a seal is the label's claim; the certifier's own list confirms it).

How many labels does Estrotone have?

8 labels are on file under this name since November 25, 2011: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 288194 (current) Entered June 22, 2023 · on the market · 60 vegetarian capsules
  2. Label 253028 Entered August 23, 2021 · off the market April 1, 2022 · 60 vegetarian capsules
  3. Label 183498 Entered November 21, 2018 · off the market June 3, 2021 · 60 vegetarian capsules
  4. Label 183473 Entered November 21, 2018 · on the market · 30 vegetarian capsules
  5. Label 38805 Entered October 27, 2014 · on the market · 120 softgels
  6. Label 38804 Entered October 27, 2014 · off the market May 11, 2018 · 60 softgels
  7. Label 26470 Entered October 25, 2013 · off the market July 18, 2014 · 120 softgels
  8. Label 2401 Entered November 25, 2011 · off the market July 18, 2014 · 60 hexane-free softgel capsules

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names New Chapter, Inc. (distributor), Brattleboro, VT. All New Chapter products.

Where next?