Estera Phase I

by Pharmanex · softgel capsule · 60 softgels

  • Off the market since October 2023 (NIH)
  • DSLD label 215061
  • Serving 2 softgels
  • 30 servings

Estera Phase I by Pharmanex lists 8 ingredients, 8 with an amount per serving of 2 softgels, such as 50 mg of vitamin B6, 500 mg of evening primrose oil, 250 mg of borage seed oil and 250 mg of chasteberry fruit (vitex agnus/castus L.) extract. Its current label entered the NIH Dietary Supplement Label Database on March 24, 2020.

What is in Estera Phase I?

Each row as the label prints it, per serving of 2 softgels. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Estera Phase I: Supplement Facts rows against the market (DSLD label 215061, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin B6as Pyridoxine HydrochlorideVitamin B6 (Form: as Pyridoxine Hydrochloride)50 mg2,941%Vitamin B6 in Estera Phase I against 15,277 products50 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg50 mg

Higher than 87% of 15,277 products listing vitamin B6 (median 6 mg).

Evening Primrose Oil500 mgEvening Primrose oil in Estera Phase I against 300 products500 mg per serving; the middle half of products list 500 mg to 1,300 mg, the median 500 mg.500 mg

50% of 300 products listing evening primrose oil give more (median 500 mg).

Borage seed Oil250 mgBorage Oil in Estera Phase I against 254 products250 mg per serving; the middle half of products list 161.5 mg to 1,000 mg, the median 515 mg.250 mg

69% of 254 products listing borage oil give more (median 515 mg).

Chasteberry fruit (Vitex agnus/castus L.) extract250 mgChastetree in Estera Phase I against 386 products250 mg per serving; the middle half of products list 50 mg to 240 mg, the median 100 mg.250 mg

Higher than 75% of 386 products listing chastetree (median 100 mg).

DiindolylmethaneDiindolylmethane Note: an indole100 mgDiindolylmethane in Estera Phase I against 425 products100 mg per serving; the middle half of products list 100 mg to 200 mg, the median 100 mg.100 mg

47% of 425 products listing diindolylmethane give more (median 100 mg).

Pomegranate fruit (Punica granatum) extract40 mgPomegranate in Estera Phase I against 860 products40 mg per serving; the middle half of products list 12.5 mg to 250 mg, the median 70.5 mg.40 mg

61% of 860 products listing pomegranate give more (median 70.5 mg).

Lignansas FlaxseedLignans (Form: from Flaxseed)15 mgLignan in Estera Phase I against 54 products15 mg per serving; the middle half of products list 20 mg to 100 mg, the median 35 mg.15 mg

85% of 54 products listing lignan give more (median 35 mg).

Genisteinas Soy Isoflavone ext.Genistein (Form: from 64% Soy Isoflavone Ext.)10 mgGenistein in Estera Phase I against 62 products10 mg per serving; the middle half of products list 8.13 mg to 30 mg, the median 24.2 mg.10 mg

66% of 62 products listing genistein give more (median 24.2 mg).

Source: NIH ODS Dietary Supplement Label Database, label 215061 (entered March 24, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Estera Phase I's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions for use: As a dietary supplement, take two (2) softgels daily, preferably one with your morning and evening meals.
Warnings
Warning: Keep out of reach of children.
If you are pregnant or lactating, or taking a prescription medication, consult a physician before using this product.
Discontinue 2 weeks prior to and after surgery. Discontinue use and consult a physician if any adverse reactions occur. Do not use if safety seal is broken or missing.
Contains soy.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 215061.

What else is on the label?

Other ingredients: Gelatin, Glycerine, Soy Oil, Beeswax, Caramel.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): 6S Quality.

How many labels does Estera Phase I have?

3 labels are on file under this name since November 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 215061 (current) Entered March 24, 2020 · off the market October 16, 2023 · 60 softgels
  2. Label 78831 Entered October 21, 2017 · off the market August 20, 2019 · 60 softgels
  3. Label 27774 Entered November 25, 2013 · off the market August 24, 2017 · 60 softgels

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names NSE Products, Inc. (distributor), Provo, UT. All Pharmanex products.

Where next?