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Doctor's Best · Non-Nutrient/Non-Botanical supplement

Double-Strength SAMe 400 mg

14 ingredients on file in the NIH Dietary Supplement Label Database. Off-market, label data preserved for reference.

14
Ingredients
5
Nutrient categories
Top 29%
By ingredient count

Double-Strength SAMe 400 mg is a non-nutrient/non-botanical supplement by Doctor's Best in tablet or pill form, listing 14 ingredients in the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. Currently listed as off-market (no longer available for purchase, but label data is preserved). Daily Value percentages shown below are based on FDA reference daily intake amounts for adults.

Product Details

Form
Tablet or Pill
Database Entry Date
2016-08-24
Ingredients
14

Supplement Facts (14 Ingredients)

Ingredient Group Amount % DV
S-Adenosyl Methionine SAMe Not disclosed on label No DV
Cellulose Cellulose Not disclosed on label No DV
Methacrylic Acid Copolymer Polyacrylate Not disclosed on label No DV
Glyceryl Behenate Glyceryl behenate Not disclosed on label No DV
Magnesium Silicate Magnesium Silicate Not disclosed on label No DV
Triethyl Citrate triethylcitrate Not disclosed on label No DV
Titanium Dioxide Titanium Dioxide Not disclosed on label No DV
Magnesium Stearate Magnesium stearate Not disclosed on label No DV
Mannitol Mannitol Not disclosed on label No DV
Glycerol Palmitostearate Glyceryl palmitostearate Not disclosed on label No DV
Silicon Dioxide Silicon Not disclosed on label No DV
Medium Chain Triglycerides Medium chain triglycerides (MCT) Not disclosed on label No DV
Sodium Carboxymethyl Starch Carboxy Methyl Starch Not disclosed on label No DV
Iron Oxide Iron Not disclosed on label No DV

How does Double-Strength SAMe 400 mg compare?

Ingredients listed on each label, against the non-nutrient/non-botanical category average of 6.9. Data from the NIH DSLD.

Double-Strength SAMe 400 mg14
1 Andro Stenelone9
Non-Nutrient/Non-Botanical average6.9

Double-Strength SAMe 400 mg lists 5 ingredients more than 1 Andro Stenelone. That is 7 above the non-nutrient/non-botanical average.

What the Label Data Shows

Double-Strength SAMe 400 mg is cataloged in the NIH Dietary Supplement Label Database (DSLD) as a non-nutrient/non-botanical supplement built from 14 ingredients from Doctor's Best, sold in tablet or pill form. These ingredients span 5 nutrient categories, other, non-nutrient/non-botanical, mineral, fiber, and 1 more, reflecting a multi-component formula rather than a single-nutrient product.

Across a broader 14-ingredient formula, 14 of 14 sit outside the FDA's reference-intake system entirely -- common at this scale, since multi-ingredient blends tend to accumulate botanicals, amino acids, and specialty compounds the FDA has never benchmarked. That's expected breadth, not a red flag on its own.

Availability status shapes how this label record is best used. This product is currently listed as off-market in the DSLD, with its label first entered into the database on 2016-08-24. An off-market listing means production and distribution under this label have stopped, but the DSLD does not delete the entry, it stays on file for historical reference and formulation-history tracking.

About the DSLD database

The DSLD is a label database, not an FDA approval list, under the 1994 DSHEA framework, dietary supplements do not require pre-market approval, and label information reflects what manufacturers self-declare rather than independent laboratory verification. This page presents factual label data for reference only and is not medical advice; consult a licensed healthcare provider before making decisions about any supplement.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) Supplement label data for Double-Strength SAMe 400 mg: ingredients, % Daily Value, market status, brand · 2026 DSLD captures manufacturer-self-declared label information; the NIH does not verify accuracy or evaluate safety/efficacy. Dietary supplements are regulated under DSHEA 1994, no pre-market FDA approval is required.

Ingredient Breakdown by Category

other
8
Methacrylic Acid Copolymer, Glyceryl Behenate, Magnesium Silicate, +5 more
non-nutrient/non-botanical
2
S-Adenosyl Methionine, Mannitol
mineral
2
Silicon Dioxide, Iron Oxide
fiber
1
Cellulose
fat
1
Medium Chain Triglycerides

Daily Value Coverage

0
Above 100% DV
0
Below 100% DV
14
No DV Established

Frequently Asked Questions

What ingredients are in Double-Strength SAMe 400 mg?
Double-Strength SAMe 400 mg contains 14 ingredients. Ingredients span 5 categories: other, non-nutrient/non-botanical, mineral, fiber, fat.
Who manufactures Double-Strength SAMe 400 mg?
Double-Strength SAMe 400 mg is was manufactured by Doctor's Best. It is classified as a Non-Nutrient/Non-Botanical supplement in tablet or pill form.
Is Double-Strength SAMe 400 mg still available for purchase?
According to the NIH DSLD database, Double-Strength SAMe 400 mg is listed as off-market and may no longer be available for purchase.
What is the serving size of Double-Strength SAMe 400 mg?
The serving size is not specified.
What type of supplement is Double-Strength SAMe 400 mg?
Double-Strength SAMe 400 mg is classified as a "Non-Nutrient/Non-Botanical" supplement in the NIH database. This category includes products primarily composed of non-nutrient/non-botanical ingredients. Across the full DSLD catalog, products fall into 9 possible categories: Vitamin, Mineral, Botanical, Amino Acid & Protein, Non-Nutrient, Fat & Fatty Acid, Multi-Vitamin & Mineral, Botanical with Nutrients, and Other Combinations.
Data Sources & Methodology

Data as of 2025. Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD).

Supplement label data sourced from the Source: NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD contains label information from dietary supplement products marketed in the United States.

Daily Value (DV) percentages are based on Source: FDA 21 CFR 101.9 Reference Daily Intake (RDI) values for adults. Products marked "Off Market" may no longer be available for purchase but their label data remains in the database for reference.

Disclaimer, Not Medical Advice

Label data from the Source: NIH Dietary Supplement Label Database (DSLD). This information is for educational and reference purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or combining any dietary supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. This page draws directly on the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.