PlainVitamins

DefensePlus

by NutriBiotic · tablet or pill · 90 vegan tablets

  • On the market (NIH)
  • UPC 7 28177 01015 7
  • DSLD label 275863
  • Serving 1 tablet
  • 90 servings

DefensePlus by NutriBiotic lists 11 ingredients, 11 with an amount per serving of 1 tablet, such as 125 mg of vitamin C, 5 mg of zinc, 250 mg of grapefruit seed extract and 100 mg of astragalus. Its current label entered the NIH Dietary Supplement Label Database on March 22, 2023.

What is in DefensePlus?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

DefensePlus: Supplement Facts rows against the market (DSLD label 275863, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Cas Meta-C125 mg207%Vitamin C in DefensePlus against 18,583 products125 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg125 mg

Higher than 56% of 18,583 products listing vitamin C (median 100 mg).

Zincas Zinc Gluconate5 mg33%Zinc in DefensePlus against 13,186 products5 mg per serving; the middle half of products list 5 mg to 15 mg, the median 11 mg.DV 11 mgUL 40 mg5 mg

72% of 13,186 products listing zinc give more (median 11 mg).

Grapefruit Seed Extract250 mgGrapefruit in DefensePlus against 220 products250 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.250 mg

Higher than 71% of 220 products listing grapefruit (median 100 mg).

Astragalus100 mgAstragalus in DefensePlus against 604 products100 mg per serving; the middle half of products list 50 mg to 405 mg, the median 132.5 mg.100 mg

52% of 604 products listing astragalus give more (median 132.5 mg).

Reishi Mushroom Extract(4:1)100 mgReishi mushroom in DefensePlus against 500 products100 mg per serving; the middle half of products list 50 mg to 500 mg, the median 180 mg.100 mg

58% of 500 products listing reishi mushroom give more (median 180 mg).

Echinacea angustifolia extract(4:1)50 mgEchinacea angustifolia in DefensePlus against 199 products50 mg per serving; the middle half of products list 50 mg to 245 mg, the median 100 mg.50 mg

68% of 199 products listing echinacea angustifolia give more (median 100 mg).

Ginger Root Extract(6:1)50 mgGinger in DefensePlus against 1,770 products50 mg per serving; the middle half of products list 25 mg to 150 mg, the median 60 mg.50 mg

51% of 1,770 products listing ginger give more (median 60 mg).

Maitake Mushroom Extract(4:1)50 mgMaitake Mushroom in DefensePlus against 327 products50 mg per serving; the middle half of products list 30 mg to 200 mg, the median 100 mg.50 mg

58% of 327 products listing maitake mushroom give more (median 100 mg).

Oregon grape50 mgOregon Grape in DefensePlus against 104 products50 mg per serving; the middle half of products list 73.75 mg to 400 mg, the median 150 mg.50 mg

78% of 104 products listing oregon grape give more (median 150 mg).

Shiitake Mushroom Extract(4:1)50 mgShiitake Mushroom in DefensePlus against 256 products50 mg per serving; the middle half of products list 33.75 mg to 200 mg, the median 100 mg.50 mg

61% of 256 products listing shiitake mushroom give more (median 100 mg).

Yarrow extract(6:1)50 mgYarrow in DefensePlus against 120 products50 mg per serving; the middle half of products list 25 mg to 155 mg, the median 50 mg.50 mg

32% of 120 products listing yarrow give more (median 50 mg).

Source: NIH ODS Dietary Supplement Label Database, label 275863 (entered March 22, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with DefensePlus's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Use: At first signs of imbalance or depressed resistance, take one tablet daily with or without meals for two weeks.
Warnings
Not recommended for children under 12 years of age.
Warning: Keep out of reach of children.
Do not exceed suggested use or use during pregnancy without consulting a licensed healthcare professional.
Allergens and what it does not contain
Made without soy, milk, egg, yeast, wheat, sweeteners, preservatives, and GMOs. Gluten free

Source: label statements in DSLD label 275863.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Stearic Acid, Dextrose, Silicon Dioxide, Magnesium Stearate, Food Glaze Coating.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Not tested on animals; Nitro Pak Naturally fresh Bacteria free environment.

How many labels does DefensePlus have?

2 labels are on file under this name since January 23, 2023: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 275863 (current) Entered March 22, 2023 · on the market · 90 vegan tablets · UPC 7 28177 01015 7
  2. Label 273483 Entered January 23, 2023 · on the market · 45 vegan tablets · UPC 7 28177 01014 0

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names NutriBiotic (manufacturer), Lakeport, CA. All NutriBiotic products.

Where next?