PlainVitamins

Betaine Plus

by Douglas Laboratories · capsule · 250 vegetarian capsules

  • On the market (NIH)
  • UPC 3 10539 98023 1
  • DSLD label 274435
  • Serving 1 vegetarian capsule
  • 250 servings

Betaine Plus by Douglas Laboratories lists 2 ingredients, 2 with an amount per serving of 1 vegetarian capsule, such as 520 mg of betaine hydrochloride and 21 mg of pepsin. Its current label entered the NIH Dietary Supplement Label Database on September 22, 2022.

What is in Betaine Plus?

Each row as the label prints it, per serving of 1 vegetarian capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Betaine Plus: Supplement Facts rows against the market (DSLD label 274435, January 2026 release)
IngredientAmount% DVAmong products listing it
Betaine Hydrochloride 520 mg Not reported Betaine Hydrochloride in Betaine Plus against 914 products520 mg per serving; the middle half of products list 25 mg to 178 mg, the median 50 mg.520 mg

Higher than 91% of 914 products listing betaine hydrochloride (median 50 mg).
Pepsinas PorcinePepsin (Form: from Porcine)(1:10,000 potency) 21 mg Not reported Pepsin in Betaine Plus against 223 products21 mg per serving; the middle half of products list 25 mg to 130 mg, the median 50 mg.21 mg

78% of 223 products listing pepsin give more (median 50 mg).

Not reported: no percentage is available for that row. A missing DSLD percentage does not establish whether an FDA reference value exists.

Source: NIH ODS Dietary Supplement Label Database, label 274435 (entered September 22, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 520 mg of betaine hydrochloride is higher than 91% of the 914 betaine hydrochloride products that print an amount; 83 list more.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Usage: As a dietary supplement, adults take 1 capsule with each meal or as directed by your health professional.
Warnings
Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health professional before using this product.
Discontinue immediately if a burning sensation occurs. Not recommended for people with ulcers.
Keep out of the reach of children.
Use only if safety seal is intact.
Allergens and what it does not contain
Gluten-free, Non-GMO
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 274435.

What else is on the label?

Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Ascorbyl Palmitate.

How many labels does Betaine Plus have?

11 labels are on file under this name since February 23, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 274435 (current) Entered September 22, 2022 · on the market · 250 vegetarian capsules · UPC 3 10539 98023 1
  2. Label 274158 Entered July 21, 2022 · on the market · 100 vegetarian capsules · UPC 3 10539 98024 8
  3. Label 246003 Entered March 25, 2021 · on the market · 100 vegetarian capsules · UPC 3 10539 01229 1
  4. Label 244604 Entered February 25, 2021 · on the market · 250 vegetarian capsules · UPC 3 10539 01771 5
  5. Label 232277 Entered August 23, 2020 · off the market January 31, 2024 · 100 vegetarian capsules · UPC 3 10539 01229 1
  6. Label 70254 Entered January 25, 2017 · on the market · 250 capsules · UPC 3 10539 01771 5
  7. Label 56717 Entered February 23, 2016 · off the market June 26, 2020 · 100 capsules · UPC 3 10539 01229 1
  8. Label 30714 Entered February 26, 2014 · off the market December 15, 2015 · 100 capsules · UPC 3 10539 01229 1
  9. Label 9810 Entered June 1, 2012 · off the market December 16, 2016 · 250 capsules · UPC 3 10539 01771 5
  10. Label 9809 Entered June 1, 2012 · off the market July 31, 2013 · 100 capsules · UPC 3 10539 01229 1
  11. Label 5375 Entered February 23, 2012 · off the market January 20, 2012 · 100 capsules · UPC 3 10539 01229 1

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Douglas Laboratories (manufacturer), Pittsburgh, PA. All Douglas Laboratories products.

Where next?