PlainVitamins

Betaine HCl Pepsin

by Pure Encapsulations · capsule · 250 capsules

  • On the market (NIH)
  • UPC 7 66298 02424 0
  • DSLD label 293907
  • Serving 1 capsule
  • 250 servings

Betaine HCl Pepsin by Pure Encapsulations lists 2 ingredients, 2 with an amount per serving of 1 capsule, such as 520 mg of betaine hydrochloride and 21 mg of pepsin. Its current label entered the NIH Dietary Supplement Label Database on July 18, 2023.

What is in Betaine HCl Pepsin?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Betaine HCl Pepsin: Supplement Facts rows against the market (DSLD label 293907, January 2026 release)
IngredientAmount% DVAmong products listing it
Betaine Hydrochloride520 mgBetaine Hydrochloride in Betaine HCl Pepsin against 914 products520 mg per serving; the middle half of products list 25 mg to 178 mg, the median 50 mg.520 mg

Higher than 91% of 914 products listing betaine hydrochloride (median 50 mg). Per day at the most servings: 1,560 mg.

Pepsin1:10,000 USP units, vegan21 mgPepsin in Betaine HCl Pepsin against 223 products21 mg per serving; the middle half of products list 25 mg to 130 mg, the median 50 mg.21 mg

78% of 223 products listing pepsin give more (median 50 mg). Per day at the most servings: 63 mg.

Source: NIH ODS Dietary Supplement Label Database, label 293907 (entered July 18, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 520 mg of betaine hydrochloride is higher than 91% of the 914 betaine hydrochloride products that print an amount; 83 list more.

The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendations: As a dietary supplement, take 1 capsule, 3 times daily, with each meal.
Warnings
Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
Discontinue immediately if a burning sensation occurs. Not recommended for people with ulcers, or a history of ulcers. Use only if safety seal is intact.
Keep out of the reach of children.
Allergens and what it does not contain
Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org
Gluten-free & non-GMO
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 293907.

What else is on the label?

Other ingredients: Cellulose, Water, Cellulose, Ascorbyl Palmitate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GFCO.org (Gluten-Free Certification Organization). Listed with: Certified gluten-free (GFCO) (a seal is the label's claim; the certifier's own list confirms it).

How many labels does Betaine HCl Pepsin have?

6 labels are on file under this name since November 21, 2018: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 293907 (current) Entered July 18, 2023 · on the market · 250 capsules · UPC 7 66298 02424 0
  2. Label 293906 Entered July 18, 2023 · on the market · 250 capsules · UPC 7 66298 00029 9
  3. Label 261715 Entered February 23, 2022 · on the market · 250 capsules · UPC 7 66298 02424 0
  4. Label 184797 Entered February 25, 2019 · off the market July 21, 2022 · 250 capsules · UPC 7 66298 00029 9
  5. Label 183929 Entered November 21, 2018 · off the market September 19, 2018 · 250 capsules · UPC 7 66298 00029 9
  6. Label 183926 Entered November 21, 2018 · off the market January 23, 2018 · 250 capsules · UPC 7 66298 00029 9

DSLD also links this label to: B-Complex (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Pure Encapsulations (manufacturer), Sudbury, MA. All Pure Encapsulations products.

Where next?