AREDS 2 Plus Softgel

by EyePromise · softgel capsule · 30 daily packs

  • Off the market since August 2023 (NIH)
  • UPC 1 85656 00009 0
  • DSLD label 249455
  • Serving 1 softgel
  • 30 servings

AREDS 2 Plus Softgel by EyePromise lists 9 ingredients, 9 with an amount per serving of 1 softgel, such as 50 mcg (2,000 IU) of vitamin D3, 268 mg of vitamin E, 250 mg of fish oil EE and 190 mg of total omega-3 fatty acids. Its current label entered the NIH Dietary Supplement Label Database on June 23, 2021.

What is in AREDS 2 Plus Softgel?

Each row as the label prints it, per serving of 1 softgel. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

AREDS 2 Plus Softgel: Supplement Facts rows against the market (DSLD label 249455, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin D3as Cholecalciferol50 mcg (2,000 IU)250%Vitamin D in AREDS 2 Plus Softgel against 14,175 products50 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg50 mcg

Higher than 81% of 14,175 products listing vitamin D (median 15 mcg).

Vitamin Eas D-Alpha-Tocopherol268 mg1,787%
Fish Oil EE250 mgFish Oil in AREDS 2 Plus Softgel against 1,990 products0.25 g per serving; the middle half of products list 1 g to 2 g, the median 1.2 g.0.25 g

95% of 1,990 products listing fish oil give more (median 1.2 g).

Total Omega-3 Fatty Acids190 mgOmega-3 in AREDS 2 Plus Softgel against 2,714 products190 mg per serving; the middle half of products list 230 mg to 1,000 mg, the median 500 mg.190 mg

79% of 2,714 products listing omega-3 give more (median 500 mg).

Eicosapentaenoic Acid100 mgEPA (Eicosapentaenoic Acid) in AREDS 2 Plus Softgel against 3,134 products100 mg per serving; the middle half of products list 120 mg to 590 mg, the median 300 mg.100 mg

78% of 3,134 products listing EPA (eicosapentaenoic acid) give more (median 300 mg).

Docosahexaenoic Acid75 mgDHA in AREDS 2 Plus Softgel against 3,627 products75 mg per serving; the middle half of products list 104 mg to 400 mg, the median 232 mg.75 mg

84% of 3,627 products listing DHA give more (median 232 mg).

Zeaxanthinas Paprika ExtractZeaxanthin (Form: from Paprika extract)10 mgZeaxanthin in AREDS 2 Plus Softgel against 1,215 products10 mg per serving; the middle half of products list 0.4 mg to 2 mg, the median 1 mg.10 mg

Higher than 97% of 1,215 products listing zeaxanthin (median 1 mg).

Luteinas Marigold flower extractLutein (Form: from Marigold flower extract PlantPart: flower)10 mgLutein in AREDS 2 Plus Softgel against 2,493 products10 mg per serving; the middle half of products list 0.5 mg to 10 mg, the median 3 mg.10 mg

Higher than 71% of 2,493 products listing lutein (median 3 mg).

Mixed Tocopherols20 mg

Source: NIH ODS Dietary Supplement Label Database, label 249455 (entered June 23, 2021), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 95% of the 1,990 products that print an amount of fish oil list more than its 0.25 g of fish oil (median 1.2 g).
  • Its 10 mg of zeaxanthin is higher than 97% of the 1,215 zeaxanthin products that print an amount; 27 list more.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with AREDS 2 Plus Softgel's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Adults take the contents of one packet daily with a meal.
Warnings
Warning: If you are pregnant or nursing, taking any medications or planning any medical procedure, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of the reach of children.
Do not use if seal under cap is broken or missing.
Contains soy & fish (Alaska Pollock).
Allergens and what it does not contain
Yeast/gluten free.
Storage
Store at room temperature: 59 degrees - 77 degrees F (15 degrees - 25 degrees C). Do not expose to excessive heat, cold or moisture.

Source: label statements in DSLD label 249455.

What else is on the label?

Other ingredients: Gelatin, Glycerin, purified Water, Corn Oil, Safflower Oil, Maltitol, Color.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Contents Certified NSF Manufactured in the U.S.A. Listed with: NSF certified (contents or GMP) (a seal is the label's claim; the certifier's own list confirms it).

How many labels does AREDS 2 Plus Softgel have?

2 labels are on file under this name since July 23, 2020: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 249455 (current) Entered June 23, 2021 · off the market August 22, 2023 · 30 daily packs · UPC 1 85656 00009 0
  2. Label 228993 Entered July 23, 2020 · off the market March 24, 2021 · 30 daily packs · UPC 1 85656 00009 0

DSLD also links this label to: AREDS 2 Plus Tablet (bundle set), AREDS 2 Plus Softgel (image difference, same product), AREDS 2 Plus Multi-Vitamin Softgel (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names ZeaVision Holdings Inc. (distributor), St. Louis, MO. All EyePromise products.

Where next?