Advanced UC-II Joint Relief

by NOW · capsule · 60 veg capsules

  • Off the market since January 2025 (NIH)
  • UPC 7 33739 03137 2
  • DSLD label 313557
  • Serving 1 veg capsule
  • 60 servings

Advanced UC-II Joint Relief by NOW lists 7 ingredients, 7 with an amount per serving of 1 veg capsule, such as 25 mcg (1,000 IU) of vitamin D3, 15 mg of calcium, 40 mg of UC-II chicken cartilage and 50 mg of aquamin. Its current label entered the NIH Dietary Supplement Label Database on July 25, 2024.

What is in Advanced UC-II Joint Relief?

Each row as the label prints it, per serving of 1 veg capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Advanced UC-II Joint Relief: Supplement Facts rows against the market (DSLD label 313557, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin D3as Cholecalciferol1,000 IU25 mcg (1,000 IU)125%Vitamin D in Advanced UC-II Joint Relief against 14,175 products25 mcg per serving; the middle half of products list 10 mcg to 25 mcg, the median 15 mcg.DV 20 mcgUL 100 mcg25 mcg

Higher than 59% of 14,175 products listing vitamin D (median 15 mcg).

Calciumas Aquamin15 mg1%Calcium in Advanced UC-II Joint Relief against 17,831 products15 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg15 mg

94% of 17,831 products listing calcium give more (median 115 mg).

UC-II Chicken Cartilagestandardized40 mgCartilage in Advanced UC-II Joint Relief against 199 products40 mg per serving; the middle half of products list 40 mg to 750 mg, the median 100 mg.40 mg

57% of 199 products listing cartilage give more (median 100 mg).

Total Collagenas undenatured Type II Collagen10 mgCollagen in Advanced UC-II Joint Relief against 1,008 products0.01 g per serving; the middle half of products list 0.1 g to 4.2 g, the median 1 g.0.01 g

90% of 1,008 products listing collagen give more (median 1 g).

Aquaminas Seaweed derived Minerals50 mg
Hyaluronic Acidas Sodium Hyaluronate25 mgHyaluronic acid in Advanced UC-II Joint Relief against 900 products25 mg per serving; the middle half of products list 10 mg to 100 mg, the median 50 mg.25 mg

61% of 900 products listing hyaluronic acid give more (median 50 mg).

Boronas Albion Bororganic Glycine3 mgBoron in Advanced UC-II Joint Relief against 3,339 products3 mg per serving; the middle half of products list 0.3 mg to 2 mg, the median 1 mg.UL 20 mg3 mg

Higher than 78% of 3,339 products listing boron (median 1 mg).

Source: NIH ODS Dietary Supplement Label Database, label 313557 (entered July 25, 2024), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 94% of the 17,831 products that print an amount of calcium list more than its 15 mg of calcium (median 115 mg).
  • 57% of the 199 products that print an amount of cartilage list more than its 40 mg of UC-II chicken cartilage (filed by NIH under cartilage) (median 100 mg).
  • 90% of the 1,008 products that print an amount of collagen list more than its 0.01 g of total collagen (filed by NIH under collagen) (median 1 g).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Advanced UC-II Joint Relief's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested usage: Take 1 capsule daily at bedtime on an empty stomach.
Warnings
Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Caution: For adults only. Keep out of reach of children.
Consult physician if pregnant/nursing, taking medication, or have a medical condition.
Allergens and what it does not contain
Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish or shellfish ingredients.

Source: label statements in DSLD label 313557.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Hypromellose, Stearic Acid, Silicon Dioxide.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): GMP Quality Assured.

How many labels does Advanced UC-II Joint Relief have?

3 labels are on file under this name since August 23, 2019: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 313557 (current) Entered July 25, 2024 · off the market January 21, 2025 · 60 veg capsules · UPC 7 33739 03137 2
  2. Label 245753 Entered March 25, 2021 · off the market February 12, 2024 · 60 veg capsules · UPC 7 33739 03137 2
  3. Label 205902 Entered August 23, 2019 · off the market September 22, 2023 · 60 veg capsules · UPC 7 33739 03137 2

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names NOW FOODS (manufacturer), Bloomingdale, IL. All NOW products.

Where next?