Advanced Probiotic

by 21st Century · capsule · 60 capsules

  • On the market (NIH)
  • UPC 7 40985 27505 4
  • DSLD label 258299
  • Serving 2 capsules
  • 30 servings

Advanced Probiotic by 21st Century lists 6 ingredients; 6 sit inside a blend without their own amounts, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on December 18, 2021.

What is in Advanced Probiotic?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Advanced Probiotic: Supplement Facts rows against the market (DSLD label 258299, January 2026 release)
IngredientAmount% DVAmong products listing it
Total Carbohydrates1 g1%Carbohydrate in Advanced Probiotic against 21,979 products1 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.1 g

74% of 21,979 products listing carbohydrate give more (median 3 g).

Proprietary BlendProprietary Blend Note: (containing 20 billion live cultures) (20 billion active cultures per serving guaranteed at time of manufacture.)1,250 mg
Lactobacillus acidophilusin the blend, no amount given
Lactobacillus caseiin the blend, no amount given
Lactobacillus rhamnosusin the blend, no amount given
Bifidobacterium longumin the blend, no amount given
Bifidobacterium animalis lactisin the blend, no amount given
Lactobacillus delbrueckiiin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 258299 (entered December 18, 2021), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 6 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Advanced Probiotic's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As a dietary supplement, adults take two (2) capsules daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage.
Warnings
Do not exceed recommended dosage.
Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.
Stop use and contact a physician if adverse reactions occur.
Keep out of reach of children.
Do not use if product appears to be tampered with or seal is broken.
Contains milk.
Allergens and what it does not contain
No added sugar, salt, yeast, preservatives, artificial flavors or colors.
Gluten free
Storage
Store at room temperature.

Source: label statements in DSLD label 258299.

What else is on the label?

Other ingredients: Maltodextrin, Gelatin, Inulin, Contains <2% of.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Guaranteed quality Laboratory tested.

How many labels does Advanced Probiotic have?

2 labels are on file under this name since August 23, 2019: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 258299 (current) Entered December 18, 2021 · on the market · 60 capsules · UPC 7 40985 27505 4
  2. Label 205484 Entered August 23, 2019 · off the market August 6, 2021 · 60 capsules · UPC 7 40985 27505 4

DSLD also links this label to: Ultra Potency Advanced Probiotic (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names 21st Century HealthCare, Inc. (manufacturer), Tempe, AZ. All 21st Century products.

Where next?