Activated B-12 Guard

by Perque · lozenge · 100 lozenges

  • On the market (NIH)
  • DSLD label 240619
  • Serving 1 lozenge
  • 100 servings

Activated B-12 Guard by Perque lists 7 ingredients, 7 with an amount per serving of 1 lozenge, such as 2,000 mcg of vitamin B12, 3.5 mg of magnesium, 295 mg of mannitol and 1 mg of organic whole cane. Its current label entered the NIH Dietary Supplement Label Database on January 22, 2021.

What is in Activated B-12 Guard?

Each row as the label prints it, per serving of 1 lozenge. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Activated B-12 Guard: Supplement Facts rows against the market (DSLD label 240619, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin B12as HydroxocobalaminVitamin B-12 (Form: as Hydroxocobalamin)2,000 mcg33,330%Vitamin B12 in Activated B-12 Guard against 14,425 products2,000 mcg per serving; the middle half of products list 6 mcg to 200 mcg, the median 36 mcg.DV 2.4 mcg2,000 mcg

Higher than 96% of 14,425 products listing vitamin B12 (median 36 mcg).

Magnesiumas C16 Alkyls, C18 Alkyls, PalmMagnesium (Form: as C16 Alkyls, and C18 Alkyls, from whole, untreated Palm PlantPart: fruit and leaf)3.5 mg1%Magnesium in Activated B-12 Guard against 14,003 products3.5 mg per serving; the middle half of products list 30 mg to 200 mg, the median 86 mg.UL 350 mgDV 420 mg3.5 mg

98% of 14,003 products listing magnesium give more (median 86 mg).

Mannitol295 mg
organic whole Cane1 mg
100% whole Cherry fruit extract3.5 mgCherry (unspecified) in Activated B-12 Guard against 37 products3.5 mg per serving; the middle half of products list 20 mg to 450 mg, the median 114 mg.3.5 mg

86% of 37 products listing cherry (unspecified) give more (median 114 mg).

Raspberry flavor8.5 mgFlavor in Activated B-12 Guard against 85 products0.0085 g per serving; the middle half of products list 0.6 g to 1.86 g, the median 1 g.0.0085 g

96% of 85 products listing flavor give more (median 1 g).

Croscarmellose Sodium25 mg

Source: NIH ODS Dietary Supplement Label Database, label 240619 (entered January 22, 2021), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 2,000 mcg of vitamin B12 is higher than 96% of the 14,425 vitamin B12 products that print an amount; 529 list more.
  • 98% of the 14,003 products that print an amount of magnesium list more than its 3.5 mg of magnesium (median 86 mg).
  • 96% of the 85 products that print an amount of flavor list more than its 0.0085 g of raspberry flavor (filed by NIH under flavor) (median 1 g).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Activated B-12 Guard's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As a dietary supplement, dissolve in mouth and then swallow (1) lozenge daily or as directed by your health professional.
Warnings
Keep out of reach of children.
Do not use product if the tamper-resistant shrink band around the cap or the inner seal beneath the cap appears to have been tampered with or is missing.
Warning: Pregnant and nursing mothers need to check with their health professional before taking supplements.
Allergens and what it does not contain
Does not contain: Citrus, MSG, wheat, gluten, corn, starch, sugar, soy, yeast, zein, sulfates, phosphates (other than coenzymes), preservatives, casein or other milk derivatives. No GMO's; No toxic minerals or metals
Full disclosure label (no hidden or inactive ingredients)
Storage
Must be stored with cap on tightly in a cool, dry place.

Source: label statements in DSLD label 240619.

What else is on the label?

Other ingredients: None.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): V (Vegetarian).

How many labels does Activated B-12 Guard have?

One label is on file, entered on January 22, 2021.

  1. Label 240619 (current) Entered January 22, 2021 · on the market · 100 lozenges

DSLD also links this label to: Activated B-12 Guard Lozenges (image difference, same product), Activated B-12 Guard 2,000 mcg Sublingual (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Perque Integrative Health (manufacturer, distributor), Ashburn, VA. All Perque products.

Where next?