PlainVitamins

Acti-Zyme

by NaturesPlus · capsule · 180 vegetarian capsules

  • On the market (NIH)
  • UPC 0 97467 44541 3
  • DSLD label 322631
  • Serving 2 capsules
  • 90 servings

Acti-Zyme by NaturesPlus lists 12 ingredients, 12 with an amount per serving of 2 capsules, such as 100 mg of fructooligosaccharides, 83 mg of amylase, 67 mg of protease and 50 mg of lactospore. Its current label entered the NIH Dietary Supplement Label Database on February 23, 2025.

What is in Acti-Zyme?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Acti-Zyme: Supplement Facts rows against the market (DSLD label 322631, January 2026 release)
IngredientAmount% DVAmong products listing it
Aminogenas Aspergillus niger, Aspergillus oryzaeProteolytic Enzyme Complex100 mg
Legumaseas Aspergillus niger, Aspergillus oryzae, Rhizopus oryzaeOligosaccharide Enzyme Complex100 mg
Fructooligosaccharidesas ChicoryLactic flora growth accelerant100 mgFructo-Oligosaccharides in Acti-Zyme against 526 products100 mg per serving; the middle half of products list 75 mg to 500 mg, the median 185 mg.100 mg

59% of 526 products listing fructo-oligosaccharides give more (median 185 mg).

Amylase1500 RAU83 mgAmylase in Acti-Zyme against 326 products83 mg per serving; the middle half of products list 5 mg to 50 mg, the median 14 mg.83 mg

Higher than 87% of 326 products listing amylase (median 14 mg).

Protease5000 HUT67 mgProteolytic Enzymes (Proteases) in Acti-Zyme against 327 products67 mg per serving; the middle half of products list 10 mg to 100 mg, the median 30 mg.67 mg

Higher than 69% of 327 products listing proteolytic enzymes (proteases) (median 30 mg).

Lactosporeas L. sporogenesmicroencapsulated pure culture of L. sporogenes, provides 300 million viable cells at the time of manufacture50 mgBacillus Coagulans in Acti-Zyme against 237 products50 mg per serving; the middle half of products list 10 mg to 66 mg, the median 20 mg.50 mg

Higher than 68% of 237 products listing bacillus coagulans (median 20 mg).

Lactase50 ALU50 mgLactase in Acti-Zyme against 138 products50 mg per serving; the middle half of products list 10 mg to 197.5 mg, the median 34 mg.50 mg

Higher than 53% of 138 products listing lactase (median 34 mg).

Lipase500 FIP50 mgLipase in Acti-Zyme against 366 products50 mg per serving; the middle half of products list 5 mg to 25 mg, the median 10 mg.50 mg

Higher than 83% of 366 products listing lipase (median 10 mg).

Cellulase500 CU50 mgCellulase in Acti-Zyme against 184 products50 mg per serving; the middle half of products list 3.74 mg to 30 mg, the median 10 mg.50 mg

Higher than 86% of 184 products listing cellulase (median 10 mg).

Oxidase5 GOTu50 mg
Bromelain100 gelatin digesting units50 mgBromelain in Acti-Zyme against 1,337 products50 mg per serving; the middle half of products list 25 mg to 200 mg, the median 50 mg.50 mg

50% of 1,337 products listing bromelain give more (median 50 mg).

Maltase32 DP5 mg
BioPerineas Piper nigrum5 mgBlack Pepper in Acti-Zyme against 2,363 products5 mg per serving; the middle half of products list 5 mg to 10 mg, the median 5 mg.5 mg

33% of 2,363 products listing black pepper give more (median 5 mg).

1-Piperoylpiperidinestandardized 95%4.75 mg

Source: NIH ODS Dietary Supplement Label Database, label 322631 (entered February 23, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Acti-Zyme's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take two capsules immediately before or after a meal.
Warnings
Warning: Keep tightly closed in a cool, dry place and out of reach of children. Not to be used by children under 12 unless recommended by a physician.
If symptoms of digestive discomfort persist, discontinue use and consult a physician.
Allergens and what it does not contain
Free from artificial colors and preservatives. Free from the common allergens wheat, soy and milk.
Gluten free
Storage
Warning: Keep tightly closed in a cool, dry place and out of reach of children.

Source: label statements in DSLD label 322631.

What else is on the label?

Other ingredients: Cellulose, Microcrystalline Cellulose, Dicalcium Phosphate, Stearic Acid, Silica, Water, Purified.

How many labels does Acti-Zyme have?

One label is on file, entered on February 23, 2025.

  1. Label 322631 (current) Entered February 23, 2025 · on the market · 180 vegetarian capsules · UPC 0 97467 44541 3

DSLD also links this label to: Acti-Zyme (package size difference, same product), Acti-Zyme (package size difference, same product), Acti-Zyme (package size difference, same product), Acti-Zyme (package size difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Natural Organics Laboratories Inc. makers of Nature's Plus (manufacturer), Amityville, NY. All NaturesPlus products.

Where next?