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Blend · Supplement ingredient

Proprietary Blend (Metabolite, constituent, extract, isolate, or combination of these)

Proprietary Blend (Metabolite, constituent, extract, isolate, or combination of these) is listed on 210 U.S. supplement product labels in the NIH DSLD, #563 of 4,614 by label frequency.

210
Products
#563 of 4,614
By frequency
Verify with NIH DSLD → · FDA Daily Value reference → · Page 1 of 5

How common is Proprietary Blend (Metabolite, constituent, extract, isolate, or combination of these)?

Number of supplement labels listing Proprietary Blend (Metabolite, constituent, extract, isolate, or combination of these) vs nearby blend ingredients

products
Source NIH Dietary Supplement Label Database (DSLD) As of 2026

Products containing Proprietary Blend (Metabolite, constituent, extract, isolate, or combination of these)

Adult 50+ Probiotic
CVS Pharmacy
15 ingredients · Non-Nutrient/Non-Botanical
On Market
Adult 50+ Probiotic
CVS Health
18 ingredients · Non-Nutrient/Non-Botanical
On Market
Adult Probiotic
CVS Pharmacy
12 ingredients · Non-Nutrient/Non-Botanical
On Market
AFP-Peptizyde with DPP IV Activity
Houston Enzymes
8 ingredients · Non-Nutrient/Non-Botanical
On Market
AlphaSorb-C 500
NOW
14 ingredients · Other Combinations
On Market
Amplified Wheybolic Extreme 60 Chocolate
GNC Pro Performance AMP
41 ingredients · Other Combinations
On Market
Amplified Wheybolic Extreme 60 Cookies & Cream
GNC Pro Performance AMP
42 ingredients · Other Combinations
On Market
Amplified Wheybolic Extreme 60 Power Chocolate Fudge
GNC Pro Performance AMP
49 ingredients · Other Combinations
On Market
Amplified Wheybolic Extreme 60 Strawberry
GNC Pro Performance AMP
42 ingredients · Other Combinations
On Market
Amplified Wheybolic Extreme 60 Vanilla
GNC Pro Performance AMP
40 ingredients · Other Combinations
On Market
Complete Feminine Balance
AZO
15 ingredients · Non-Nutrient/Non-Botanical
On Market
Dark Matter Blue Raspberry
MHP Maximum Human Performance
41 ingredients · Other Combinations
On Market
Dark Matter Fruit Punch
MHP Maximum Human Performance
42 ingredients · Other Combinations
On Market
Digestive Care Probiotic
Equate
9 ingredients · Non-Nutrient/Non-Botanical
On Market
Digestive Enzymes
GNC Mega Men
18 ingredients · Non-Nutrient/Non-Botanical
On Market
Digestive Enzymes
GNC Women's Ultra Mega
20 ingredients · Non-Nutrient/Non-Botanical
On Market
Digestive Enzymes
GNC Beyond Raw
20 ingredients · Non-Nutrient/Non-Botanical
On Market
Digestive Enzymes
Vimerson Health
13 ingredients · Non-Nutrient/Non-Botanical
On Market
Digestive Enzymes + Probiotics
Arazo Nutrition
13 ingredients · Non-Nutrient/Non-Botanical
On Market
Digestive Health Probiotic
Equate
9 ingredients · Non-Nutrient/Non-Botanical
On Market
DigestMore Fats & Proteins
Renew Life
19 ingredients · Non-Nutrient/Non-Botanical
On Market
Dual Protection
AZO
20 ingredients · Non-Nutrient/Non-Botanical
On Market
Extra Strength Probiotic & Acidophilus Formula
Windmill Rx Premium Vitamins
12 ingredients · Other Combinations
On Market
Formula 2 Starch Digest
NESS Nutritional Enzyme Support System
9 ingredients · Non-Nutrient/Non-Botanical
On Market
Formula 2 Starch Digest
NESS Nutritional Enzyme Support System
9 ingredients · Non-Nutrient/Non-Botanical
On Market
Full Spectrum Optimum Enzymes
Bluebonnet
13 ingredients · Other Combinations
On Market
Full Spectrum Optimum Enzymes
Bluebonnet
13 ingredients · Other Combinations
On Market
Hair Growth Supplement
Viviscal
21 ingredients · Other Combinations
On Market
Healthy Eyes Lutigold Extra
Puritan's Pride
8 ingredients · Non-Nutrient/Non-Botanical
On Market
Healthy Eyes Lutigold Extra
Puritan's Pride
8 ingredients · Non-Nutrient/Non-Botanical
On Market
Herbal Actives Ultra Açai 1200 MG/120 MG Acai Polyphenols Extended Release Mini-Tabs
Nature's Plus
11 ingredients · Botanical
On Market
Herbal Flora Probiotic
Mountain Meadow Herbs
20 ingredients · Non-Nutrient/Non-Botanical
On Market
High Potency Multi Enzyme Vegetarian Formula
Natural Factors
20 ingredients · Non-Nutrient/Non-Botanical
On Market
Intensive Strength Digest 13
Nature's Bounty
17 ingredients · Non-Nutrient/Non-Botanical
On Market
Joint Soother With Omega 3-6-9
Vitamin World
30 ingredients · Other Combinations
On Market
Lutigold Extra
Puritan's Pride
9 ingredients · Non-Nutrient/Non-Botanical
On Market
Mass XXplosion Anabolic Workout Formula Grape
Nutrex Research
39 ingredients · Other Combinations
On Market
Mass XXplosion Fruit Punch
Nutrex Research
38 ingredients · Other Combinations
On Market
Meltdown Fat Incinerator
VPX
22 ingredients · Other Combinations
On Market
Methylburn Extreme
MuscleMeds
22 ingredients · Other Combinations
On Market
Micellar Casein Cookies & Cream
BodyTech
29 ingredients · Amino acid/Protein
On Market
NanoPro Vegan Vanilla Toffee Flavor
BioPharma Scientific
21 ingredients · Other Combinations
On Market
Natural Acidophilus Probiotic Complex
Rite Aid Pharmacy
8 ingredients · Non-Nutrient/Non-Botanical
On Market
Olive Leaf Extract 300 mg
Pure Vegan
4 ingredients · Botanical
On Market
Omega-Zyme Ultra Ultimate Digestive Enzyme Blend
Garden of Life
34 ingredients · Other Combinations
On Market
Primadophilus Probifia Pearls
Nature's Way
13 ingredients · Non-Nutrient/Non-Botanical
On Market
Probiotic 10x
Signature Care
15 ingredients · Non-Nutrient/Non-Botanical
On Market
Probiotic Acidophilus
Puritan's Pride
9 ingredients · Non-Nutrient/Non-Botanical
On Market
Probiotic Pearls Acidophilus
Nature's Way
8 ingredients · Non-Nutrient/Non-Botanical
On Market
Probiotic Pearls Complete
Nature's Way
13 ingredients · Non-Nutrient/Non-Botanical
On Market

Nearby Ingredients in Blend

Other ingredients in the Blend category cataloged in the NIH DSLD. Useful for comparing how common different nutrients are across the US supplement market.

Compare Proprietary Blend (Metabolite, constituent, extract, isolate, or combination of these) vs Blend →

Blend
7,220 products · Blend
Proprietary Blend
6,707 products · Blend
Blend (Combination)
4,333 products · Blend
Proprietary Blend (Combination)
4,178 products · Blend
Proprietary Blend (Herb/Botanical)
3,359 products · Blend

Nationwide ingredients with similar DSLD presence

Two peer sets for Proprietary Blend (Metabolite, constituent, extract, isolate, or combination of these): closest on total DSLD label listings (210 here) and closest on distinct brands that list it (87 here). Peers exclude the same DSLD category, and rows stay link-disjoint so each axis is a distinct neighborhood.

Similar label frequency

Nearest other ingredients by distinct DSLD product labels (floored at ≥50), outside this category.

Frequently asked about Proprietary Blend (Metabolite, constituent, extract, isolate, or combination of these)

How many supplement products contain Proprietary Blend (Metabolite, constituent, extract, isolate, or combination of these)? ▼
210 supplement product labels in the NIH DSLD currently lists Proprietary Blend (Metabolite, constituent, extract, isolate, or combination of these) as an ingredient. By label frequency it ranks #563 of 4,614 among ingredients PlainVitamins ranks (same sort as /rankings/most-common-ingredients). Browse them below.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD). Regulatory reference: Source: Dietary Supplement Health and Education Act (DSHEA), 1994, 21 U.S.C. § 321(ff).

Disclaimer, Not Medical Advice: Information on this page is based on manufacturer-declared label data and is provided for educational and reference purposes only. It does not constitute medical, nutritional, or health advice. Consult a licensed healthcare provider before starting, stopping, or combining any supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Read our methodology , how this data is sourced, computed, and verified.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. Ingredient figures are computed directly from the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.