Ultimate Probiotic 12/12 Formula 12 Billion

by Natural Factors · capsule · 120 vegetarian capsules

  • On the market (NIH)
  • UPC 0 68958 01848 5
  • DSLD label 220946
  • Serving 1 vegetarian capsule

Ultimate Probiotic 12/12 Formula 12 Billion by Natural Factors lists 12 ingredients; 12 give their count of live cultures or enzyme activity instead of a weight. Its current label entered the NIH Dietary Supplement Label Database on May 22, 2020.

What is in Ultimate Probiotic 12/12 Formula 12 Billion?

Each row as the label prints it, per serving of 1 vegetarian capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Ultimate Probiotic 12/12 Formula 12 Billion: Supplement Facts rows against the market (DSLD label 220946, January 2026 release)
IngredientAmount% DVAmong products listing it
Proprietary Synergistic BlendProprietary Synergistic Blend Note: (total active cell count) (12 billion CFU)
Lactobacillus casei (HA-108)Lactobacillus casei (HA-108) PlantPart: whole cell Genus: Lactobacillus Species: casei Note: (human) (3 billion CFU)
Lactobacillus rhamnosus (HA-111)Lactobacillus rhamnosus (HA-111) PlantPart: whole cell Genus: Lactobacillus Species: rhamnosus Note: (human) (1.44 billion CFU)
Lactobacillus rhamnosus (HA-114)Lactobacillus rhamnosus (HA-114) PlantPart: whole cell Genus: Lactobacillus Species: rhamnosus Note: (human) (1.2 billion CFU)
Lactobacillus acidophilus (HA-122)Lactobacillus acidophilus (HA-122) PlantPart: whole cell Genus: Lactobacillus Species: acidophilus Note: (human) (1.2 billion CFU)
Bifidobacterium breve (HA-129)Bifidobacterium breve (HA-129) PlantPart: whole cell Genus: Bifidobacterium Species: breve Note: (human) (1.2 billion CFU)
Bifidobacterium longum (HA-135)Bifidobacterium longum (HA-135) PlantPart: whole cell Genus: Bifidobacterium Species: longum Note: (human) (1.2 billion CFU)
Lactobacillus plantarum (HA-119)Lactobacillus plantarum (HA-119) PlantPart: whole cell Genus: Lactobacillus Species: plantarum Note: (plant) (1.2 billion CFU)
Bifidobacterium bifidum (HA-132)Bifidobacterium bifidum (HA-132) PlantPart: whole cell Genus: Bifidobacterium Species: bifidum Note: (human) (0.6 billion CFU)
Lactobacillus fermentum (HA-179)Lactobacillus fermentum (HA-179) PlantPart: whole cell Genus: Lactobacillus Species: fermentum Note: (dairy) (0.6 billion CFU)
Bifidobacterium lactis (HA-194)Bifidobacterium lactis (HA-194) PlantPart: whole cell Genus: Bifidobacterium Species: lactis Note: (dairy) (0.12 billion CFU)
Lactobacillus paracasei (HA-196)Lactobacillus paracasei (HA-196) PlantPart: whole cell Genus: Lactobacillus Species: paracasei Note: (dairy) (0.12 billion CFU)
Lactobacillus salivarius (HA-118)Lactobacillus salivarius (HA-118) PlantPart: whole cell Genus: Lactobacillus Species: salivarius Note: (human) (0.12 billion CFU)

Source: NIH ODS Dietary Supplement Label Database, label 220946 (entered May 22, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 12 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

4 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Usage: 1 capsule 3 times per day or as directed by a health professional. If you are taking antibiotics, wait 2 hours before ingesting probiotics.
Warnings
If you are taking antibiotics, wait 2 hours before ingesting probiotics. Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.
Keep out of the reach of children.
Sealed for your protection. Do not use if seal is broken.
Contains milk and soy.
Allergens and what it does not contain
Contains no artificial colors, preservatives, or sweeteners; no sugar, wheat, gluten, yeast, corn, egg, fish, shellfish, salt, tree nuts, or GMOs.
Storage
For freshness, store in a cool, dry place.
For maximum strength, refrigerate.

Source: label statements in DSLD label 220946.

What else is on the label?

Other ingredients: Maltodextrin, Vegetarian Capsule, FOS, Inulin, Magnesium Stearate, Silica, Ascorbic Acid.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): isura Non-GMO - Mass spec Documentation - Lab tested; Purity & potency guaranteed.

How many labels does Ultimate Probiotic 12/12 Formula 12 Billion have?

8 labels are on file under this name since November 25, 2014: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 220946 (current) Entered May 22, 2020 · on the market · 120 vegetarian capsules · UPC 0 68958 01848 5
  2. Label 220944 Entered May 22, 2020 · on the market · 60 vegetarian capsules · UPC 0 68958 01847 8
  3. Label 75344 Entered August 22, 2017 · off the market April 7, 2020 · 120 vegetarian capsules · UPC 0 68958 01848 5
  4. Label 75333 Entered June 23, 2017 · on the market · 60 vegetarian capsules · UPC 0 68958 01847 8
  5. Label 52893 Entered October 22, 2015 · off the market May 6, 2017 · 120 vegetarian capsules · UPC 0 68958 01848 5
  6. Label 51432 Entered October 22, 2015 · off the market May 6, 2017 · 60 vegetarian capsules · UPC 0 68958 01847 8
  7. Label 39245 Entered November 25, 2014 · off the market September 16, 2015 · 120 vegetarian capsules · UPC 0 68958 01848 5
  8. Label 39244 Entered November 25, 2014 · off the market May 6, 2017 · 60 vegetarian capsules · UPC 0 68958 01847 8

DSLD also links this label to: Ultimate Probiotic 12/12 Formula (package size difference, same product), Ultimate Probiotic 12/12 Formula (image difference, same product), Ultimate Probiotic 12/12 Formula (package size difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Natural Factors Canada (manufacturer). All Natural Factors products.

Where next?