Tone & Define

by GNC Total Lean Advanced · tablet or pill · 60 tablets

  • On the market (NIH)
  • DSLD label 47848
  • Serving 1 tablet

Tone & Define by GNC Total Lean Advanced lists 8 ingredients, 2 with an amount per serving of 1 tablet; 6 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on July 24, 2015.

What is in Tone & Define?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Tone & Define: Supplement Facts rows against the market (DSLD label 47848, January 2026 release)
IngredientAmount% DVAmong products listing it
Body Composition Matrixno amount given
Citri-Sculpt(TM) Blend Proprietary Blend450 mg
Grapefruit extractin the blend, no amount given
Sweet Orange extractin the blend, no amount given
Blood Orange extractin the blend, no amount given
Guarana extractGuarana extract PlantPart: seed Genus: Paullina Species: cupana Note: 20% Flavanones= 90 mgin the blend, no amount given
Meratrim Proprietary Blend400 mg
Sphaeranthus indicus extractin the blend, no amount given
Garcinia mangostana extractas 7-Hydroxyfrullanolide, Alpha-MangostinGarcinia mangostana extract (Form: 3% 7-Hydroxyfrullanolide Note: =12 mg, 2% Alpha-Mangostin Note: =8 mg) PlantPart: fruit rind Genus: Garcinia Species: mangostanain the blend, no amount given
Metabolic Activation Blendno amount given
Garcinia Cambogia fruit extractas Hydroxycitric AcidGarcinia Cambogia fruit extract (Form: 50% Hydroxycitric Acid Note: = 125 mg) PlantPart: fruit Genus: Garcinia Species: cambogia250 mgGarcinia in Tone & Define against 676 products250 mg per serving; the middle half of products list 200 mg to 1,000 mg, the median 500 mg.250 mg

69% of 676 products listing garcinia give more (median 500 mg). Per day at the most servings: 500 mg.

Egcgas Decaffeinated Green Tea extractEGCG (Form: from Decaffeinated Green Tea extract (Form: standardized to 40% EGCG Note: =10 mg) PlantPart: leaf Genus: Camellia Species: sinensis Note: )22.2 mgEGCG in Tone & Define against 291 products22.2 mg per serving; the middle half of products list 50 mg to 150 mg, the median 100 mg.22.2 mg

89% of 291 products listing EGCG give more (median 100 mg). Per day at the most servings: 44.4 mg.

Source: NIH ODS Dietary Supplement Label Database, label 47848 (entered July 24, 2015), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient; 6 ingredients sit inside a blend, so their amounts cannot be compared.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Tone & Define's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As a dietary supplement, take one tablet twice daily. For maximum results, use for at least 12 weeks in conjunction with a healthy diet and exercise program. To supercharge your metabolism, use in combination with Total Lean(TM) Advanced metabolic Elite(TM). For personalized stacking suggestions and to learn more, visit www.GNC.com/TotalLeanAdvanced.
Warnings
Keep out of reach of children.
With less than 20 mg of caffeine per serving, this no-jitters tablet can be taken individually or stacked with a high-energy thermogenic for supercharged metabolism support!
Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.
Discontinue use two weeks prior to surgery.
Each serving provides 18 mg of caffeine.
Allergens and what it does not contain
Gluten Free
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 47848.

What else is on the label?

Other ingredients: Cellulose, Crospovidone, Stearic Acid, Magnesium Stearate, Food Glaze, Medium Chain Triglycerides, Titanium Dioxide, Mica, Artificial colors, natural Vanilla Mint flavor, Sucralose.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Gf Gluten Free; Meratrim(R).

How many labels does Tone & Define have?

One label is on file, entered on July 24, 2015.

  1. Label 47848 (current) Entered July 24, 2015 · on the market · 60 tablets

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names General Nutrition Corporation (distributor), Pittsburgh, PA. All GNC Total Lean Advanced products.

Where next?